Results 11 to 20 of about 291,082 (298)
Repurposing antiviral agents against mucormycosis. [PDF]
PLoS ONEMucormycosis is a life-threatening fungal infection with limited treatment options and high mortality rates among immunocompromised individuals. To identify new therapeutic strategies, we screened a library of 618 antiviral compounds against Rhizopus ...
Ammar A Khan +2 more
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AntiviralDB: an expert-curated database of antiviral agents against human infectious diseases [PDF]
mBioViral infectious diseases have caused millions of deaths worldwide. Antiviral agents are critical for controlling these infections; however, an open-access database dedicated specifically to antiviral agents remains unavailable.
Jie Huang +10 more
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Discovery and development of safe-in-man broad-spectrum antiviral agents
International Journal of Infectious Diseases, 2020 Viral diseases are one of the leading causes of morbidity and mortality in the world. Virus-specific vaccines and antiviral drugs are the most powerful tools to combat viral diseases. However, broad-spectrum antiviral agents (BSAAs, i.e.
Petter I. Andersen +12 more
doaj +3 more sources
Inhaled Dry Powder of Antiviral Agents: A Promising Approach to Treating Respiratory Viral Pathogens [PDF]
VirusesInhaled dry powder formulations of antiviral agents represent a novel and potentially transformative approach to managing respiratory viral infections. Traditional antiviral therapies in the form of tablets or capsules often face limitations in terms of ...
Tushar Saha +5 more
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Carbazole Derivatives as Antiviral Agents: An Overview
Molecules, 2019 Viruses represent the most common cause of infectious diseases worldwide and those with rapid propagation and high infection rates cause human and animal pandemics. These fast-spreading diseases are generally treated with antiviral drugs but, often, drug
Anna Caruso +7 more
doaj +3 more sources
Breaking the chains: Advancements in antiviral strategies to combat Nipah virus infections [PDF]
International Journal of One Health, 2023 Nipah virus (NiV) is a highly pathogenic zoonotic virus that has caused several outbreaks with high fatality rates in humans and animals, thus, requiring a “One Health” approach. No specific treatment or vaccine is available for NiV infection, making the
Fredmoore L. Orosco
doaj +1 more source
Journal of Global Antimicrobial Resistance, 2022 : Objectives: As a host restriction factor, apolipoprotein B messenger RNA-editing enzyme catalytic polypeptide-like 3G (APOBEC3G or A3G) has been shown to suppress the replication of several viruses including hepatitis B virus (HBV).
Jin Hu +6 more
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Establishment and application of a high-throughput screening model for cell adhesion inhibitors
Frontiers in Pharmacology, 2023 The cell adhesion between leukocytes and endothelial cells plays an important balanced role in the pathophysiological function, while excessive adhesion caused by etiological agents is associated with the occurrence and development of many acute and ...
Han Sun +18 more
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Curcumin as an Antiviral Agent [PDF]
Viruses, 2020 Curcumin, the primary curcuminoid compound found in turmeric spice, has shown broad activity as an antimicrobial agent, limiting the replication of many different fungi, bacteria and viruses. In this review, we summarize recent studies supporting the development of curcumin and its derivatives as broad-spectrum antiviral agents.
Morgan R. Jennings, Robin J. Parks
openaire +3 more sources
Recent Research Progress: Discovery of Anti-Plant Virus Agents Based on Natural Scaffold
Frontiers in Chemistry, 2022 Plant virus diseases, also known as “plant cancers”, cause serious harm to the agriculture of the world and huge economic losses every year. Antiviral agents are one of the most effective ways to control plant virus diseases.
Jixiang Chen +6 more
doaj +1 more source