Results 11 to 20 of about 1,793,389 (302)

Broad-spectrum antiviral agents [PDF]

Frontiers in Microbiology, 2015
Development of highly effective, broad-spectrum antiviral agents is the major objective shared by the fields of virology and pharmaceutics. Antiviral drug development has focused on targeting viral entry and replication, as well as modulating cellular ...
Jun-Da eZhu, Wen eMeng, Xiao-Jia eWang, Hwa-Chain Robert Wang   +3 more
doaj   +2 more sources

Ribonucleases as antiviral agents [PDF]

Molecular Biology, 2014
Many ribonucleases (RNases) are able to inhibit the reproduction of viruses in infected cell cultures and laboratory animals, but the molecular mechanisms of their antiviral activity remain unclear. The review discusses the well-known RNases that possess established antiviral effects, including both intracellular RNases (RNase L, MCPIP1 protein, and ...
Ilinskaya O., Mahmud R.
openaire   +6 more sources

Efficacy decrease of antiviral agents when administered to ongoing hepatitis C virus infections in cell culture

Frontiers in Microbiology, 2022
We report a quantification of the decrease of effectiveness of antiviral agents directed to hepatitis C virus, when the agents are added during an ongoing infection in cell culture vs. when they are added at the beginning of the infection.
Carlos García-Crespo, Carlos García-Crespo, Lucía Vázquez-Sirvent, Lucía Vázquez-Sirvent, Pilar Somovilla, Pilar Somovilla, María Eugenia Soria, María Eugenia Soria, María Eugenia Soria, Isabel Gallego, Isabel Gallego, Ana Isabel de Ávila, Ana Isabel de Ávila, Brenda Martínez-González, Brenda Martínez-González, Antoni Durán-Pastor, Esteban Domingo, Esteban Domingo, Celia Perales, Celia Perales, Celia Perales, Celia Perales   +21 more
doaj   +1 more source

Silver Nanoparticles as Potential Antiviral Agents

Pharmaceutics, 2021
Since the early 1990s, nanotechnology has led to new horizons in nanomedicine, which encompasses all spheres of science including chemistry, material science, biology, and biotechnology.
Zubair Ahmed Ratan, Fazla Rabbi Mashrur, Anisha Parsub Chhoan, Sadi Md. Shahriar, Mohammad Faisal Haidere, Nusrat Jahan Runa, Sunggyu Kim, Dae-Hyuk Kweon, Hassan Hosseinzadeh, Jae Youl Cho   +9 more
doaj   +1 more source

Antiviral Agents: Discovery to Resistance

Viruses, 2020
In the midst of the SARS-CoV-2/Covid-19 outbreak the need for research into, and development of, antiviral agents is brought into sharp focus worldwide for scientists, governments and the public alike [...]
Catherine S. Adamson
doaj   +1 more source

Incidence of acute kidney injury (AKI) and outcomes in COVID-19 patients with and without antiviral medications: A retrospective study.

PLoS ONE, 2023
BackgroundAcute kidney injury is a complication of COVID-19 and is associated with severity. Despite no specific antiviral treatment strategy, lopinavir/ritonavir and remdesivir have been used.
Seyed Majid Mousavi Movahed, Hamed Akhavizadegan, Fatemeh Dolatkhani, Samaneh Akbarpour, Seyed Aria Nejadghaderi, Morvarid Najafi, Parmida Sadat Pezeshki, Akram Khalili Noushabadi, Hoomaan Ghasemi   +8 more
doaj   +1 more source

Inhibition of SARS Coronavirus Infection In Vitro with Clinically Approved Antiviral Drugs

Emerging Infectious Diseases, 2004
Severe acute respiratory syndrome (SARS) is an infectious disease caused by a newly identified human coronavirus (SARS-CoV). Currently, no effective drug exists to treat SARS-CoV infection.
Emily L.C. Tan, Eng Eong Ooi, Chin-Yo Lin, Hwee Cheng Tan, Ai Ee Ling, Bing Lim, Lawrence W. Stanton   +6 more
doaj   +1 more source

Population-Wide Emergence of Antiviral Resistance during Pandemic Influenza [PDF]

, 2008
Background: The emergence of neuraminidase inhibitor resistance has raised concerns about the prudent use of antiviral drugs in response to the next influenza pandemic.
Wu, Jianhong, Röst, Gergely, Moghadas Seyed M., Jianhong Wu, Christopher S Bowman, Wu Jianhong, Bowman, Christopher S., Galvani, Alison P., R\uf6st, Gergely, Moghadas, Seyed M., Gergely Röst, Seyed M Moghadas, Bowman Christopher S., Röst Gergely   +13 more
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Seven classes of antiviral agents [PDF]

, 2022
The viral epidemics and pandemics have stimulated the development of known and the discovery of novel antiviral agents. About a hundred mono- and combination antiviral drugs have been already approved, whereas thousands are in development.
Tenson, Tanel, Kainov, Denis E., Kainov, Denis, Zusinaite, Eva, Bjørås, Magnar, Ahmad, Shahzaib, Ianevski, Aleksandr, Bjoras, Magnar, Oksenych, Valentyn, Anunnitipat, Kraipit   +9 more
core   +1 more source

Novel activities of safe-in-human broad-spectrum antiviral agents [PDF]

, 2018
According to the WHO, there is an urgent need for better control of viral diseases. Re-positioning existing safe-in-human antiviral agents from one viral disease to another could play a pivotal role in this process.
Metelitsa, Natalja, Lysvand, Hilde,, Telling, Kaidi,, Anders Bergqvist, Kuivanen, Suvi,, Aittokallio, Tero,, Evander, Magnus,, Rebecca J. Cox, Valkonen, Miia,, Tenson, Tanel,, Evander, Magnus, Magnar Bjørås, Öhrmalm, Christina,, Laura Kakkola, Hukkanen, Veijo,, Lutsar, Irja, Svein Arne Nordbø, Zusinaite, Eva,, Strand, Mårten,, Bjørås, Magnar, Paavilainen, Henrik,, Bergqvist, Anders,, Olli Vapalahti, Aleksandr Ianevski, Strand, Mårten, Uga Dumpis, Öhrmalm, Christina, Anu Kantele, Bergqvist, Anders, Mona Teppor, Metelitsa, Natalja,, Laajala, Mira,, Irja Lutsar, Kallio-Kokko, Hannimari,, Mira Laajala, Merits, Andres, Astra Vitkauskiene, Ilkka Julkunen, Oksenych, Valentyn,, Tenson, Tanel, Julkunen, Ilkka,, Bjorås, Magnar,, Dumpis, Uga, Kallio-Kokko, Hannimari, Magnus Evander, Mårten Strand, Kåre Bondeson, Bondeson, Kåre,, Telling, Kaidi, Hilde Lysvand, Veijo Hukkanen, Vitkauskiene, Astra,, Bjoras, Magnar, Bondeson, Kåre, Kainov, Denis,, Varpu Marjomaki, Aittokallio, Tero, Vapalahti, Olli, Ianevski, Aleksandr,, Vitkauskiene, Astra, Eva Zusinaite, Kuivanen, Suvi, Suvi Kuivanen, Andres Merits, Oksenych, Valentyn, Letjuka, Pille, Christina Öhrmalm, Kantele, Anu, Vapalahti, Olli,, Miia Valkonen, Valkonen, Miia, Paavilainen, Henrik, Hukkanen, Veijo, Kantele, Anu,, Zusinaite, Eva, Julkunen, Ilkka, Tero Aittokallio, Kaidi Telling, Teppor, Mona,, Natalja Metelitsa, Valentyn Oksenych, Kainov, Denis, Marjomäki, Varpu, Marjomaki, Varpu,, Ianevski, Aleksandr, Tanel Tenson, Nordbo, Svein Arne,, Cox, Rebecca J.,, Nordbø, Svein Arne, Lysvand, Hilde, Denis Kainov, Laajala, Mira, Pille Letjuka, Letjuka, Pille,, Teppor, Mona, Kakkola, Laura, Nordbo, Svein Arne, Cox, Rebecca J., Henrik Paavilainen, Lutsar, Irja,, Hannimari Kallio-Kokko, Dumpis, Uga,, Merits, Andres,, Kakkola, Laura,   +103 more
core   +1 more source