Polyclonal and monoclonal B lymphocytes response in HCV-infected patients treated with direct-acting antiviral agents [PDF]
Hepatitis C virus (HCV) chronic infection can be associated with extrahepatic manifestations such as mixed cryoglobulinaemia and lymphoproliferative disorders that are endowed with increased rates of morbidity and all-cause mortality.
Burra, Patrizia +13 more
core +1 more source
Can biopolymers act as antiviral agents?
editorial
J. Seppala, S. Borandeh
doaj +1 more source
Hepatitis C virus cell-cell transmission and resistance to direct-acting antiviral agents [PDF]
Hepatitis C virus (HCV) is transmitted between hepatocytes via classical cell entry but also uses direct cell-cell transfer to infect neighboring hepatocytes.
A Owsianka +72 more
core +7 more sources
A Review of Commonly Prescribed Antiviral and Antiretroviral Agents [PDF]
Objective: To review the pharmacologic properties of and uses for the most commonly prescribed antiviral agents. Data Sources: A MEDLINE/PubMed search (1966–September 2010) was conducted for English-language articles using the terms HIV, hepatitis ...
Devito Inge, Lisa +3 more
core +1 more source
Antiviral agents are drugs approved in the USA by the Food and Drug Administration (FDA) for the treatment or control of viral infections. Available antiviral agents mainly target stages in the viral life cycle. The target stages in the viral life cycle are; viral attachment to host cell, uncoating, synthesis of viral mRNA, translation of mRNA ...
Paintsil, E., Cheng, Yung-Chi
openaire +2 more sources
Complexes of Ruthenium(II) as Promising Dual-Active Agents against Cancer and Viral Infections
Poor responses to medical care and the failure of pharmacological treatment for many high-frequency diseases, such as cancer and viral infections, have been widely documented.
Assunta D’Amato +6 more
doaj +1 more source
From actually toxic to highly specific – novel drugs against poxviruses [PDF]
The potential use of variola virus, the causative agent of smallpox, as a bioweapon and the endemic presence of monkeypox virus in Africa demonstrate the need for better therapies for orthopoxvirus infections. Chemotherapeutic approaches to control viral
Sliva, Katja, Schnierle, Barbara
core +2 more sources
Hepatitis C virus molecular evolution: Transmission, disease progression and antiviral therapy [PDF]
Hepatitis C virus (HCV) infection represents an important public health problem worldwide. Reduction of HCV morbidity and mortality is a current challenge owned to several viral and host factors.
Carpio Pedroza, Juan Carlos +10 more
core +1 more source
G-quadruplexes and G-quadruplex ligands: targets and tools in antiviral therapy [PDF]
G-quadruplexes (G4s) are non-canonical nucleic acids secondary structures that form within guanine-rich strands of regulatory genomic regions. G4s have been extensively described in the human genome, especially in telomeres and oncogene promoters; in ...
Richter, Sara N, Ruggiero, Emanuela
core +1 more source
Entecavir versus tenofovir in patients with chronic hepatitis B: Enemies or partners in the prevention of hepatocellular carcinoma [PDF]
Over the past several decades, entecavir (ETV) and tenofovir disoproxil fumarate (TDF) have remained the first-line antiviral agents in several international guidelines.
Sung Won Lee +3 more
doaj +1 more source

