Structural basis of nectin-1 recognition by pseudorabies virus glycoprotein D. [PDF]
PLoS Pathogens, 2017 An early and yet indispensable step in the alphaherpesvirus infection is the engagement of host receptors by the viral envelope glycoprotein D (gD). Of the thus-far identified gD receptors, nectin-1 is likely the most effective in terms of its wide usage
An Li +8 more
doaj +1 more source
Signalling C-Type Lectins in Antimicrobial Immunity [PDF]
, 2013 Funding: This work was funded by the Wellcome Trust, Medical Research Council and the University of Aberdeen. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Peer ...
Brown, Gordon D., Drummond, Rebecca A.
core +2 more sources
Identification of unique B virus (Macacine Herpesvirus 1) epitopes of zoonotic and macaque isolates using monoclonal antibodies. [PDF]
PLoS ONE, 2017 Our overall aim is to develop epitope-based assays for accurate differential diagnosis of B virus zoonotic infections in humans. Antibodies to cross-reacting epitopes on human-simplexviruses continue to confound the interpretation of current assays where
David Katz +9 more
doaj +1 more source
Corticosteroids for the common cold [PDF]
, 2015 BACKGROUND: The common cold is a frequent illness, which, although benign and self limiting, results in many consultations to primary care and considerable loss of school or work days. Current symptomatic treatments have limited benefit.
Del Mar, Chris B. +5 more
core +1 more source
The landscape of viral associations in human cancers [PDF]
, 2020 Here, as part of the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, for which whole-genome and—for a subset—whole-transcriptome sequencing data from 2,658 cancers across 38 tumor types was aggregated, we systematically investigated potential ...
Alawi, Malik +14 more
core +3 more sources
Tegument Assembly and Secondary Envelopment of Alphaherpesviruses. [PDF]
, 2015 Alphaherpesviruses like herpes simplex virus are large DNA viruses characterized by their ability to establish lifelong latent infection in neurons. As for all herpesviruses, alphaherpesvirus virions contain a protein-rich layer called "tegument" that ...
Crump, Colin M +2 more
core +3 more sources
Regulated expression of galectin-1 after in vitro productive infection with herpes simplex virus type 1: implications for T cell apoptosis [PDF]
, 2005 Apoptosis of cytotoxic T lymphocytes by herpes simplex virus type-1 (HSV-1) has been reported to be a relevant mechanism of viral immune evasion. Galectin-1 (Gal-1), an endogenous lectin involved in T-cell apoptosis, has recently gained considerable ...
Gonzalez, Maria Ines +5 more
core +1 more source
Swiss recommendations for the management of genital herpes and herpes simplex virus infection of the neonate. [PDF]
, 2004 Genital herpes is being recognised as a medical problem of increasing importance. Diagnosis and management are complex. The present recommendations have been established by a multidisciplinary panel of specialists and endorsed by all Swiss medical ...
Gerber, Stefan
core +1 more source
Critical Care, 2020 Background Herpes simplex virus (HSV) replication can be detected in the respiratory secretions of a high proportion of ventilated intensive care unit (ICU) patients. However, the clinical significance remains poorly defined.
Lukas Schuierer +8 more
doaj +1 more source
Pregnancy and contraceptive use among women participating in an HIV prevention trial in Tanzania. [PDF]
, 2012 OBJECTIVES: Information on pregnancy rates and factors associated with pregnancy and contraceptive use is important for clinical trials in women in sub-Saharan Africa where withdrawal of investigational products may be required in the event of pregnancy ...
Baisley, Kathy +8 more
core +1 more source