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Viruses, 2020 Human herpes simplex viruses (HSV) 1 and 2 are extremely common human pathogens with overlapping disease spectra. Infections due to HSV-1 and HSV-2 are distinguished in clinical settings using sequence-based “typing” assays.
Hong Xie +2 more
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Comparative evaluation of Savanna HSV 1+2/VZV multiplex assay and Simplexa HSV 1&2 and VZV direct kits for rapid molecular detection of HSV-1, HSV-2, and VZV [PDF]
Microbiology SpectrumHerpes simplex virus (HSV-1 and HSV-2) and varicella-zoster virus (VZV) cause cutaneous and mucocutaneous lesions. Primary infection and secondary reactivations affect the mouth, genitalia, and dermis at other bodily regions.
Blake W. Buchan +12 more
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HSV-1 as a Potential Driver of Alzheimer’s Disease [PDF]
PathogensHerpes simplex virus type 1 (HSV-1) is a continuous health challenge, and current antiviral treatments cannot cure the virus. As life expectancy continues to increase worldwide, HSV-1 should remain a focus to minimize its associated health complications ...
Dar-Yin Li, Eun Seok Choi, Xiaoyong Bao
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Viruses, 2023 (1) Background: Epigallocatechin gallate (EGCG) has been recognized as a flavonoid showing antiviral activity against various types of DNA and RNA viruses.
Malgorzata Krzyzowska +8 more
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Viruses, 2021 In the face of new emerging respiratory viruses, such as SARS-CoV2, vaccines and drug therapies are not immediately available to curb the spread of infection.
Ling Jin, Wendy Black, Teresa Sawyer
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BMJ Open, 2023 Objectives To assess the seroprevalence of herpes simplex virus (HSV) types 1 and 2 in patients infected with HIV in Nigeria.Design Cross-sectional design from January to June 2019.Setting Federal Teaching Hospital, Ebonyi State, Nigeria.Participants A ...
Euslar Nnenna Onu +10 more
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Hsp90 Inhibitors Prevent HSV-1 Replication by Directly Targeting UL42-Hsp90 Complex
Frontiers in Microbiology, 2022 Herpes simplex virus type I (HSV-1) is a member of the Alphaherpesvirinae family, which could initiate labial herpes caused by the reactivation of HSV-1 primary infection, and secondary infection even causes herpes encephalitis.
Shurong Qin +29 more
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“Non-Essential” Proteins of HSV-1 with Essential Roles In Vivo: A Comprehensive Review
Viruses, 2020 Viruses encode for structural proteins that participate in virion formation and include capsid and envelope proteins. In addition, viruses encode for an array of non-structural accessory proteins important for replication, spread, and immune evasion in ...
Christos Dogrammatzis +2 more
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Detection of herpes simplex virus in oral tongue squamous cell carcinoma
Frontiers in Pharmacology, 2023 Introduction: Oral tongue squamous cell carcinoma (OTSCC) is the most common cancer of the oral cavity. Contradictory results have been observed on the involvement of herpes simplex virus 1 (HSV-1) in oral squamous cell carcinomas.
Tiina Koivikko +20 more
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Vaccines, 2020 Infections with herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) are a global health burden. Besides painful oral or genital lesions in otherwise healthy subjects, both viruses can cause devastating morbidity and mortality in immune-compromised and
Christiane Silke Heilingloh +9 more
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