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Potential for HSV-1 vaccination to reduce risk of HSV-1 encephalitis and/or Alzheimer’s disease?
Professor Itzhaki and her team report an interesting experiment in which vaccination of mice with mixed HSV-1 glycoproteins significantly reduced detectable latent HSV-1 in brain (from 41% to 7%) 5 months after subsequent challenge by ear scarification with a non-lethal dose of HSV-1 [18]. This work follows the earlier demonstration by other groups [6 –
openaire +3 more sources
Visual teach‐and‐repeat (VTR) navigation allows robots to learn and follow routes without building a full metric map. We show that navigation accuracy for VTR can be improved by integrating a topological map with error‐drift correction based on stereo vision.
Fuhai Ling, Ze Huang, Tony J. Prescott
wiley +1 more source
The enzymatic depolymerization of fucoidans from brown algae allowed the production of their standardized derivatives with different biological activities.
Natalya V. Krylova +10 more
doaj +1 more source
Task‐Oriented Path Planning Towards Autonomous Sensor Network Deployment in Rainforest Canopies
An informative path planner for drone‐based deployment of wireless sensor networks in rainforest canopies is presented, addressing key challenges in large‐scale biodiversity monitoring. By integrating canopy surface detection with connectivity‐aware sampling under strict flight constraints, the approach enables efficient and reliable aerial sensor ...
Rita Santos Raminhos, Salua Hamaza
wiley +1 more source
Herpes simplex virus infections among rural residents in eastern China
Background Herpes simplex virus (HSV) has two types: HSV-1 and HSV-2. Both infect epithelial cells and establish latent infections in neurons causing an infection that persists for life. Information on age- and gender-specific seroprevalence of HSV-1 and
Chen Li +5 more
doaj +1 more source
Genital HSV-1 infections [PDF]
Importantly, individuals with genital HSV-1 are still at risk of HSV-2 acquisition In the past decade, investigations have amply documented the increase in the frequency of genital herpes simplex virus type 1 (HSV-1) compared with genital HSV-2 infection.
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A developmentally inspired bioprinting approach enables the fabrication of pluripotent tissues that undergo shape‐morphing and in situ cardiac lineage specification. This method employs embedded bioprinting to deposit iPSCs within soft granular hydrogels to create pluripotent tissue constructs that undergo cell‐mediated shape morphogenesis.
Ankita Pramanick +8 more
wiley +1 more source
Herpes simplex virus type 1 and 2 in mucocutaneous infections
Herpes simplex virus (HSV) type 1 and 2 are both known to cause mucosal and skin infections. HSV-1 is regarded as the main virus type in the orofacial region, whereas HSV-2 is mainly associated with genital infections.
Hannamari Välimaa
doaj +1 more source
RT promotes VG161 replication in BC and its immunostimulatory transgenes expression, which is mediated by the upregulation of GADD34 and HVEM caused by RT. The combination therapy with VG161 and RT increases the abundances of tumor‐infiltrating lymphocytes and elicits potent systemic antitumor immunity, thereby effectively inhibiting local tumors and ...
Lijuan Lyu +13 more
wiley +1 more source
Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of
Johannes Jungwirth +10 more
wiley +1 more source

