The SUMO Ligase Protein Inhibitor of Activated STAT 1 (PIAS1) is a constituent PML-NB protein that contributes to the intrinsic antiviral immune response to herpes simplex virus 1 (HSV-1) [PDF]
, 2016 Aspects of intrinsic antiviral immunity are mediated by promyelocytic leukaemia (PML)-nuclear body (PML-NB) constituent proteins. During herpesvirus infection, these antiviral proteins are independently recruited to nuclear domains that contain infecting
Boutell, Chris +7 more
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Improved Long-term Expression from Helper Virus-free HSV-1 Vectors Packaged Using Combinations of Mutated HSV-1 Proteins that Include the UL13 Protein Kinase and Specific Components of the VP16 Transcriptional Complex [PDF]
, 2011 Background: Herpes Simplex Virus (HSV-1) gene expression is thought to shut off recombinant gene expression from HSV-1 vectors; however, in a helper virus-free HSV-1 vector system, a number of promoters support only short-term expression.
Geller, Alfred I. +2 more
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Virology Journal, 2007 Background Herpes simplex virus type 2 (HSV-2) is a major cofactor of human immunodeficiency virus type 1 (HIV-1) sexual acquisition and transmission.
Bélec Laurent +7 more
doaj +1 more source
Intervirology, 1993 Neuroinvasiveness, the capacity of virus to enter and progress through the nervous system, may be accomplished by hematogenous or neural routes. We have been interested in defining HSV-1 genes specifically concerned with the neural pathway. In one system (involving HSV strain Ang), we have found that a single amino acid change in glycoprotein D, a ...
openaire +2 more sources
CD200R1 Supports HSV-1 Viral Replication and Licenses Pro-Inflammatory Signaling Functions of TLR2 [PDF]
, 2000 The CD200R1:CD200 axis is traditionally considered to limit tissue inflammation by down-regulating pro-inflammatory signaling in myeloid cells bearing the receptor.
Soberman, Roy Jason +12 more
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PLoS ONE, 2015 BackgroundHerpes simplex virus type 1 (HSV-1) commonly causes orolabial ulcers, while HSV-2 commonly causes genital ulcers. However, HSV-1 is an increasing cause of genital infection.
Katharine J Looker +6 more
doaj +1 more source
Natural infection with herpes simplex virus type 1 (HSV-1) induces humoral and T cell responses to the HSV-1 glycoprotein H:L complex [PDF]
, 2000 The glycoproteins of herpes simplex virus type 1 (HSV-1) are important targets for the immune system in the control of HSV-1 infections. The humoral and T cell responses to the glycoprotein (g)H(t(His)):gL complex of HSV-1 were ...
Kooij, A. van +7 more
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تغییرات اپیدمیولوژیHSV-1: اثر آن بر روی وقوع هرپس چشمی [PDF]
Archives of Razi Institute, 2016 HSV-1 شیوع گستردهای در بین جمعیتهای انسانی دارد و نتیجه آن ایجاد طیف گستردهای از عفونتها و بیماریها میباشد.اگرچه،HSV-2 عامل اصلی هرپس جنسی میباشد، هرپس جنسی ناشی از HSV-1 نیز در حال افزایش میباشد. این مقاله تغییرات اپیدمیولوژیکی HSV-1 را که شامل
بهمن عابدی کیاسری +1 more
doaj +1 more source
Coincident onset of multiple sclerosis and herpes simplex virus 1 encephalitis. a case report [PDF]
, 2017 Background: Along with vitamin D, smoking, body mass index and others, Epstein Barr virus, other herpesviruses and human endogenous retroviruses represent plausible environmental risk factors for multiple sclerosis.
Buscarinu, M. C. +7 more
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Herpes simplex virus assembly and spread in murine skin after infection from the outside
Journal of VirologyHerpes simplex viruses (HSV) cause many skin diseases, particularly in immunocompromised patients. HSV-1 infection of murine skin recapitulates many aspects of human pathology.
Timmy Richardo +13 more
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