Results 41 to 50 of about 21,325,054 (309)

Assessing the contribution of the herpes simplex virus DNA polymerase to spontaneous mutations

BMC Infectious Diseases, 2002
Background The thymidine kinase (tk) mutagenesis assay is often utilized to determine the frequency of herpes simplex virus (HSV) replication-mediated mutations. Using this assay, clinical and laboratory HSV-2 isolates were shown to have a 10- to 80-fold
Leary Jeffry J, Halsey Wendy M, Bartus Joan O, Wittrock Robert J, Nguyen Tammy T, Quail Matthew R, Duffy Karen E, Bacon Teresa H, Sarisky Robert T   +8 more
doaj   +1 more source

Anti-HSV-1 gRNAs impair HSV-1 replication.

, 2016
a) Vero cells were transduced with the indicated gRNAs and subsequently infected with HSV-1-eGFP at an MOI of 0.05. To assess the percentage of virus-infected cells, eGFP-expression was analyzed by flow cytometry at 2 dpi.
Anita C. Schürch (173257), Saskia M. Imhof (2863670), Emmanuel J. H. J. Wiertz (124100), Ferdy R. van Diemen (2863673), Elisabeth M. Kruse (2863667), Robert Jan Lebbink (341442), Marjolein J. G. Hooykaas (2863664), Carlijn E. Bruggeling (2863676), Monique Nijhuis (89548), Petra M. van Ham (214475)   +9 more
core   +1 more source

The innate immune response to HSV-1: glycoprotein mediated activation of dendritic cells [PDF]

, 2009
Herpes Simplex Virus (HSV) – 1 also known as Human Herpes Virus (HHV) – 1 is a common infectious agent of humans which can cause a wide variety of clinical outcomes, ranging from mild mucocutaneous lesions to long term morbidity and possible mortality.
Reske, A., Reske, A
core  

Residual‐Lithium‐to‐LiF Conversion Enables a LiF–Fluorinated Carbon Interphase for Reconstruction‐Resistant Ni‐Rich Cathodes

Advanced Functional Materials, EarlyView.
A fluorine‐rich acrylate monomer (PFHEA) was solvent‐free applied to NCM90 and thermally decomposed under Ar to convert residual lithium into LiF and form a pre‐built LiF/fluorinated amorphous carbon (LiF/FC) interphase. The LiF/FC layer suppresses NiO rock‐salt reconstruction and microcrack propagation, lowers interfacial resistance, and improves Li ...
Pangyu Kim, Juyeon Han, Junhyeok Kim, Younghoon Kim, Eunha Seo, Dain Kim, Jeeyoung Yoo   +6 more
wiley   +1 more source

Digital Microneedles for Multiplexed Transdermal Sensing via Fluorescent QR Codes

Advanced Materials, EarlyView.
Digital fluorescent microneedles encode biochemical information in skin into scannable QR codes through threshold‐activated probes that generate binary on/off signals. By transforming analog fluorescence into discrete digital patterns, this platform enables calibration‐free, multiplexed transdermal sensing of physiologically relevant biomarkers ...
Farbod Abazar, Shahrokh Vahabi, Elena Bellotti, Martina Corsi, Irene Nocera, Paola Orlandi, Guido Bocci, Giuseppe Barillaro   +7 more
wiley   +1 more source

Left out but not Forgotten: Should Closer Attention be Paid to Coinfection with Herpes Simplex Virus Type 1 and HIV?

Canadian Journal of Infectious Diseases and Medical Microbiology, 2009
Herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) are among the most common coinfections seen in individuals infected with HIV-1. Most research on HSV-HIV coinfection has focused on HSV-2, and in particular, on its impact on HIV transmission.
Darrell H S Tan, Rupert Kaul, Sharon Walsmley   +2 more
doaj   +1 more source

IFI16 Restricts HSV-1 Replication by Accumulating on the HSV-1 Genome, Repressing HSV-1 Gene Expression, and Directly or Indirectly Modulating Histone Modifications

PLoS Pathogens, 2014
Interferon-γ inducible factor 16 (IFI16) is a multifunctional nuclear protein involved in transcriptional regulation, induction of interferon-β (IFN-β), and activation of the inflammasome response. It interacts with the sugar-phosphate backbone of dsDNA and modulates viral and cellular transcription through largely undetermined mechanisms.
Karen E Johnson, Virginie Bottero, Stephanie Flaherty, Sujoy Dutta, Vivek Vikram Singh, Bala Chandran   +5 more
openaire   +4 more sources

HSV-1 glycoproteins do not interact with HCMV glycoproteins.

, 2016
(A) ARPE-19 cells were transduced with Ad vectors expressing Ad-tet-trans alone (tet, as a negative control), HSV-1 gH/gL, or HSV-1 gH/gL along with HCMV gB (as indicated along the top of the panel).
Paul W. Howard (3173379), Todd W. Wisner (307889), David C. Johnson (307895), Adam L. Vanarsdall (307887)   +3 more
core   +1 more source

HSV-1 protein ICP27 interacted with MOV10 to antagonize MOV10 restriction of HSV-1 replication.

, 2022
(A) Left, volcano plot for the differences between protein levels in the MOV10 specific pulldown group and control pulldown group as analyzed by LC-MS/MS. Red dots represent candidate interacting proteins according to the selection criteria of p t-test).
Ze Xiang (12085909), Dongli Pan (2475040), Feiyang Ji (5393894), Xiyuan Yang (12085906), Zeyu Sun (2932719), Keyi Ren (9182103)   +5 more
core   +1 more source

Ultra‐High‐Throughput Discovery of Multifunctional Polyphenolic Coatings on Droplet Microarrays

Advanced Materials, EarlyView.
An ultra‐high‐throughput (UHT) combinatorial strategy enables the miniaturized synthesis and screening of ≈30 000 polyamine‐polyphenolic (PaPp) coatings using droplet microarrays (DMA). This approach reveals hundreds of previously unknown fluorescent, redox‐active, and antibacterial materials, including multifunctional, cell‐compatible surfaces ...
Vania Tanda Widyaya, Joaquín E. Urrutia Gómez, Paul Reuß, Alexander Welle, Rolf A. Gattung, Jana Mayer, Peter Krolla, Markus Reischl, Pascal Friederich, Anna A. Popova, Thomas Schwartz, Pavel A. Levkin   +11 more
wiley   +1 more source