Results 1 to 10 of about 95,433 (302)

Herpes simplex virus infections among rural residents in eastern China [PDF]

BMC Infectious Diseases, 2011
Background Herpes simplex virus (HSV) has two types: HSV-1 and HSV-2. Both infect epithelial cells and establish latent infections in neurons causing an infection that persists for life. Information on age- and gender-specific seroprevalence of HSV-1 and
Chen Li, Su Meifang, Feng Jifu, He Na, Lin Haijiang, Gao Meiyang   +5 more
doaj   +3 more sources

A herpes simplex virus 2 (HSV-2) glycoprotein D-expressing nonreplicating dominant-negative HSV-2 virus vaccine is superior to a gD2 subunit vaccine against HSV-2 genital infection in guinea pigs. [PDF]

PLoS ONE, 2014
We recently constructed a novel non-replicating dominant-negative HSV-2 recombinant viral vaccine (CJ2-gD2) capable of expressing various HSV-2 antigens that are dominant targets of HSV-2-specific CD8 T-cell response.
Pengwei Zhang, Lining Xie, John W Balliet, Danilo R Casimiro, Feng Yao   +4 more
doaj   +5 more sources

Seroepidemiology of Herpes Simplex virus type 1 and 2 in Western and Southern Switzerland in adults aged 25–74 in 1992–93 : a population-based study [PDF]

BMC Infectious Diseases, 2004
Background Genital herpes is one of the most prevalent sexually-transmitted diseases, and accounts for a substantial morbidity. Genital herpes puts newborns at risk for very severe disease and also increases the risk of horizontal HIV transmission.
Sahli Roland, Barazzoni Fabrizio, Wietlisbach Vincent, Bünzli Dominique, Meylan Pascal RA   +4 more
doaj   +6 more sources

Detection, quantification and genotyping of Herpes Simplex Virus in cervicovaginal secretions by real-time PCR: a cross sectional survey [PDF]

Virology Journal, 2005
Background Herpes Simplex Virus (HSV) Genital Ulcer Disease (GUD) is an important public health problem, whose interaction with HIV results in mutually enhancing epidemics. Conventional methods for detecting HSV tend to be slow and insensitive.
Natividad-Sancho Angels, Bailey Robin L, Aryee Esther AN, Kaye Steve, Holland Martin J   +4 more
doaj   +5 more sources

Expansion of the HSV-2-specific T cell repertoire in skin after immunotherapeutic HSV-2 vaccine. [PDF]

JCI Insight
The skin at the site of HSV-2 reactivation is enriched for HSV-2-specific T cells. To evaluate whether an immunotherapeutic vaccine could elicit skin-based memory T cells, we studied skin biopsies and HSV-2-reactive CD4+ T cells from PBMCs by T cell receptor (TCR) β chain (TRB) sequencing before and after vaccination with a replication-incompetent ...
Ford ES, Li AZ, Laing KJ, Dong L, Diem K, Jing L, Mayer-Blackwell K, Basu K, Ott M, Tartaglia J, Gurunathan S, Reid JL, Ecsedi M, Chapuis AG, Huang ML, Magaret AS, Johnston C, Zhu J, Koelle DM, Corey L.   +19 more
europepmc   +3 more sources

Epidemiological Characteristics of HSV-1 and HSV-2 in 177,599 Patients Based on PCR Testing in South Korea (2018–2022) [PDF]

Pathogens
HSV-1 is associated with oral lesions and non-sexual transmission; HSV-2 is primarily transmitted through sexual contact and causes genital infections.
Hyeong Ho Kim, Sung Hun Jang, Jeong Su Han, Jae-Sik Jeon, Jae Kyung Kim   +4 more
doaj   +2 more sources

Antibody to HSV gD peptide induced by vaccination does not protect against HSV-2 infection in HSV-2 seronegative women. [PDF]

PLoS ONE, 2017
BACKGROUND:In the HIV-1 vaccine trial RV144, ALVAC-HIV prime with an AIDSVAX® B/E boost reduced HIV-1 acquisition by 31% at 42 months post first vaccination.
Peter B Gilbert, Jean-Louis Excler, Georgia D Tomaras, Lindsay N Carpp, Barton F Haynes, Hua-Xin Liao, David C Montefiori, Supachai Rerks-Ngarm, Punnee Pitisuttithum, Sorachai Nitayaphan, Jaranit Kaewkungwal, Gustavo H Kijak, Sodsai Tovanabutra, Donald P Francis, Carter Lee, Faruk Sinangil, Phillip W Berman, Nakorn Premsri, Prayura Kunasol, Robert J O'Connell, Nelson L Michael, Merlin L Robb, Rhoda Morrow, Lawrence Corey, Jerome H Kim   +24 more
doaj   +5 more sources

Analysis of HSV1/2 Infection Reveals an Association between HSV-2 Reactivation and Pregnancy [PDF]

Viruses
The herpes simplex viruses consist of the strains, HSV-1 and HSV-2, which are prevalent worldwide and lack a definitive cure. We aimed to explore the specific characteristics of HSV 1 and 2 infections, such as differences between gender assigned at birth,
Sara Dovrat, Adar Shabat, Anat Yahav-Dovrat, Zvia Soufiev, Ella Mendelson, Ela Kashi-Zagdoun, Galia Rahav   +6 more
doaj   +2 more sources

Elsberg syndrome in HSV-2 infection

IDCases, 2023
Elsberg syndrome (ES) is a neuroinflammatory disease that causes acute or subacute lumbosacral radiculitis, with or without myelitis which accounts for approximately 5-10% of cauda equina syndrome and myelitis. We herein present a case of a middle-aged female who recently returned from the Dominican Republic and presented to the emergency room with ...
Omar Belfaqeeh, Alexandria Markley, Mudita Patel, Brian Markoff, Georgina Osorio   +4 more
openaire   +3 more sources

Seroprevalence of antibodies to herpes simplex virus 1 and 2 in patients with HIV positive from Ebonyi State, Nigeria: a cross-sectional study

BMJ Open, 2023
Objectives To assess the seroprevalence of herpes simplex virus (HSV) types 1 and 2 in patients infected with HIV in Nigeria.Design Cross-sectional design from January to June 2019.Setting Federal Teaching Hospital, Ebonyi State, Nigeria.Participants A ...
Euslar Nnenna Onu, Uchechukwu Onyeukwu Ekuma, Hawraa K Judi, Ogbonnaya Ogbu, Nworie Okoro, Gloria C Ajugwo, Sousan Akrami, Chukwudum S Okoli, Chioma Ngozi Anyanwu, Morteza Saki, Peter Anyigor Edeh   +10 more
doaj   +1 more source