Results 1 to 10 of about 17,745,525 (306)
The innate immune response to HSV-1: glycoprotein mediated activation of dendritic cells [PDF]
, 2009 Herpes Simplex Virus (HSV) – 1 also known as Human Herpes Virus (HHV) – 1 is a common infectious agent of humans which can cause a wide variety of clinical outcomes, ranging from mild mucocutaneous lesions to long term morbidity and possible mortality.
Reske, A., Reske, A
core
HSV-2 replication in the cornea of C57Bl/6J mice.
, 2018 (A) Schematic representation of the murine ocular HSV-2 infection model. Both corneas of anesthetized mice were scarified. Virus was placed on the eyes using 105 pfu/eye. Ocular swabs were taken at the indicated time points post infection (p.i.). Animals
Michael Spohn (3163416) +5 more
core +1 more source
HSV-1 infection upregulates PAD expression in human fibroblasts.
, 2023 (A) mRNA expression levels of PADI isoforms by RT-qPCR of HSV-1-infected (8 and 16 hpi) vs uninfected (mock) HFFs were normalized to the housekeeping gene glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and expressed as mean fold change ± SEM over mock ...
Leonard Barasa (16318086) +17 more
core +1 more source
HSV-2 infection dynamics from a single model simulation.
, 2018 (A) Total (summed across the whole simulation region) HSV-2 and infected epithelial cell counts. (B) Cytokine concentration. (C) CD4+ and CD8+ T cell densities. (D) Percentage of the modelled region damaged due to lesion development.
Catherine M. Byrne (5147228) +2 more
core +1 more source
HSV-2 PLNP LFA receiver operating characteristic (ROC) curves.
, 2019 Each panel member was tested and analyzed in replicate (n = 2), by SeraCare, Inc, using HerpeSelect 2 ELISA from Focus Diagnostics, and the resulting absorbance mean was normalized to generate signal-to-cutoff ratios (reactivity ratios).
Katerina Kourentzi (415276) +11 more
core +1 more source
HSV-1 infection induces IL-1β expression and secretion.
, 2020 (A–K) TPA-differentiated THP-1 macrophages were treated with 2 μM Nigericin for 2 h, and infected with HSV-1 at MOI = 0.1, 0.2, 0.4 and 0.8 for 8 h (A, C, E and G), infected with HSV-1 at MOI = 0.8 for 2, 4, 6 and 8 h (B, D, F and H), or transfected with
Weijie Chen (1321836) +16 more
core +1 more source
, 2019 A sample is diluted and then mixed with PLNPs functionalized with goat anti-human IgGs to form human IgG-PLNP complexes that were dispensed onto the sample pad of the LFA strip.
Katerina Kourentzi (415276) +11 more
core +1 more source
Anti-HSV-1 gRNAs impair HSV-1 replication.
, 2016 a) Vero cells were transduced with the indicated gRNAs and subsequently infected with HSV-1-eGFP at an MOI of 0.05. To assess the percentage of virus-infected cells, eGFP-expression was analyzed by flow cytometry at 2 dpi.
Anita C. Schürch (173257) +9 more
core +1 more source
HSV-2 infection dynamics from multiple model simulations.
, 2018 (A) Total quantity of HSV-2 within the simulation region at all time points throughout year long simulations. (B) Total percentage of tissue damage within the simulation region at all time points throughout year long simulations.
Catherine M. Byrne (5147228) +2 more
core +1 more source
HSV-1 infection promotes the STING-NLRP3 interaction.
, 2020 (A, B) TPA-differentiated THP-1 macrophages were mock-infected or infected with HSV-1 (MOI = 1) for 4 h (A) or 2 h and 4 h (B). (C, D) HEK293T cells (C) and Hela cells (D) were co-transfected with pFlag-STING and pHA-NLRP3, and then infected with HSV-1 ...
Weijie Chen (1321836) +16 more
core +1 more source