Results 31 to 40 of about 82,727 (264)

Antibody to HSV gD peptide induced by vaccination does not protect against HSV-2 infection in HSV-2 seronegative women. [PDF]

PLoS ONE, 2017
BACKGROUND:In the HIV-1 vaccine trial RV144, ALVAC-HIV prime with an AIDSVAX® B/E boost reduced HIV-1 acquisition by 31% at 42 months post first vaccination.
Peter B Gilbert, Jean-Louis Excler, Georgia D Tomaras, Lindsay N Carpp, Barton F Haynes, Hua-Xin Liao, David C Montefiori, Supachai Rerks-Ngarm, Punnee Pitisuttithum, Sorachai Nitayaphan, Jaranit Kaewkungwal, Gustavo H Kijak, Sodsai Tovanabutra, Donald P Francis, Carter Lee, Faruk Sinangil, Phillip W Berman, Nakorn Premsri, Prayura Kunasol, Robert J O'Connell, Nelson L Michael, Merlin L Robb, Rhoda Morrow, Lawrence Corey, Jerome H Kim   +24 more
doaj   +1 more source

Melatonin as an immunomodulator in combined therapy of herpesvirus skin diseases associated with HIV

Journal of V. N. Karazin Kharkiv National University: Series Medicine, 2021
Introduction. Highly active antiretroviral therapy is the current standard of care for patients with HIV/AIDS. Although antiretroviral therapy is etiotropic, quite effective in reducing viral load, recurrent opportunistic infections can lead to adverse ...
Diana Dorosh, Tetiana Liadova, Popov Mykola, Iryna Kadygrob, Mykola Shustval, Roman Malantschuk   +5 more
doaj   +1 more source

Vaginal HSV-2 Infection and Tissue Analysis [PDF]

BIO-PROTOCOL, 2017
The vaginal murine HSV-2 infection model is very useful in studying mucosal immunity against HSV-2 ( Overall et al., 1975 ; Renis et al., 1976 ; Parr and Parr, 2003). Histologically, the vagina of Depo-Provera-treated mice is lined by a single layer of mucus secreting columnar epithelial cells overlying two to three layers of proliferative cells.
Marie Iversen, Søren Paludan, Christian Holm   +2 more
openaire   +3 more sources

Detection of Viruses associated with Herpes Labialis Patients in Babylon Province Pre and Post Treatment with Low Power Laser Therapy (Diode Laser)

Medical Journal of Babylon
Background:The secondary or recurrent herpetic infections (RHIs) are caused by herpes simplex virus (HSV) type-1 and type-2. low-power laser therapy 940 nm may consider one of the best and most optimistic and optional local therapeutic and biological ...
Ahmed Jaber Aboob, Ali Mihsen Hussein Alyassiri, Younis Abdulridha Alkhafaji   +2 more
doaj   +1 more source

Seroprevalence of Herpes Simplex Virus Type 1 and 2 in Taiwan and Risk Factor Analysis, 2007. [PDF]

PLoS ONE, 2015
Herpes simplex virus type 1 (HSV-1) and 2 (HSV-2) are common human pathogens and might cause severe illness. Following primary infection, the viruses establish lifelong latent infection and are transmitted by close contact, both sexual and nonsexual ...
Jen-Hsiang Shen, Kuan-Ying Arthur Huang, Chen Chao-Yu, Chih-Jung Chen, Tzou-Yien Lin, Yhu-Chering Huang   +5 more
doaj   +1 more source

Inactivating and inhibitory activity of dry ethanol extracts of wormwood (Artemisia spp.) on herpes simplex virus of the 2 type in vitro

Юг России: экология, развитие
Aim. In vitro assessment of the inactivating and inhibitory activity of dry ethanol extracts of various wormwood species (Artemisia spp.) native to the Novosibirsk region and Altai Republic on the replication of Herpes simplex virus type 2 (HSV-2 ...
E. I. Каzachinskaia, V. V. Velichko, V. D. Romanova, D. S. Kruglov, D. L. Prokusheva, A. A. Chepurnov, Yu. V. Коnonova, L. Fu, Sh. Shao, M. A. Gulyaeva, A. M. Shestopalov   +10 more
doaj   +1 more source

An HSV-2 nucleoside-modified mRNA genital herpes vaccine containing glycoproteins gC, gD, and gE protects mice against HSV-1 genital lesions and latent infection.

PLoS Pathogens, 2020
HSV-1 causes 50% of first-time genital herpes infections in resource-rich countries and affects 190 million people worldwide. A prophylactic herpes vaccine is needed to protect against genital infections by both HSV-1 and HSV-2. Previously our laboratory
Kevin P Egan, Lauren M Hook, Alexis Naughton, Norbert Pardi, Sita Awasthi, Gary H Cohen, Drew Weissman, Harvey M Friedman   +7 more
doaj   +1 more source

Herpes Simplex Virus 1 and 2 Infections during Differentiation of Human Cortical Neurons

Viruses, 2021
Herpes simplex virus 1 (HSV-1) and 2 (HSV-2) can infect the central nervous system (CNS) with dire consequences; in children and adults, HSV-1 may cause focal encephalitis, while HSV-2 causes meningitis.
Petra Bergström, Edward Trybala, Charlotta E. Eriksson, Maria Johansson, Tugce Munise Satir, Sibylle Widéhn, Stefanie Fruhwürth, Wojciech Michno, Faisal Hayat Nazir, Jörg Hanrieder, Soren Riis Paludan, Lotta Agholme, Henrik Zetterberg, Tomas Bergström   +13 more
doaj   +1 more source

Incidence and risk factors for herpes simplex virus type 2 seroconversion among pregnant women in Uganda: A prospective study

Journal of Infection in Developing Countries, 2016
Introduction: Herpes simplex virus type 2 (HSV-2) acquired during pregnancy is associated with adverse outcomes such as perinatal HSV-2 transmission. HSV-2 seroconversion occurs within four weeks of HSV-2 acquisition.
Sarah Nakubulwa, Dan K Kaye, Freddie Bwanga, Nazarius Mbona Tumwesigye, Edith Nakku-Joloba, Florence M Mirembe   +5 more
doaj   +1 more source

Herpes simplex virus interference with immunity: Focus on dendritic cells

Virulence, 2021
Herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) are highly prevalent in the human population. These viruses cause lifelong infections by establishing latency in neurons and undergo sporadic reactivations that promote recurrent disease and new ...
Farías MA, Duarte LF, Tognarelli EI, González PA   +3 more
doaj   +1 more source