Results 11 to 20 of about 17,745,525 (306)

Antibody to HSV gD peptide induced by vaccination does not protect against HSV-2 infection in HSV-2 seronegative women. [PDF]

PLoS ONE, 2017
BACKGROUND:In the HIV-1 vaccine trial RV144, ALVAC-HIV prime with an AIDSVAX® B/E boost reduced HIV-1 acquisition by 31% at 42 months post first vaccination.
Peter B Gilbert, Jean-Louis Excler, Georgia D Tomaras, Lindsay N Carpp, Barton F Haynes, Hua-Xin Liao, David C Montefiori, Supachai Rerks-Ngarm, Punnee Pitisuttithum, Sorachai Nitayaphan, Jaranit Kaewkungwal, Gustavo H Kijak, Sodsai Tovanabutra, Donald P Francis, Carter Lee, Faruk Sinangil, Phillip W Berman, Nakorn Premsri, Prayura Kunasol, Robert J O'Connell, Nelson L Michael, Merlin L Robb, Rhoda Morrow, Lawrence Corey, Jerome H Kim   +24 more
doaj   +6 more sources

Herpes Simplex Virus Mistyping due to HSV-1 × HSV-2 Interspecies Recombination in Viral Gene Encoding Glycoprotein B

Viruses, 2020
Human herpes simplex viruses (HSV) 1 and 2 are extremely common human pathogens with overlapping disease spectra. Infections due to HSV-1 and HSV-2 are distinguished in clinical settings using sequence-based “typing” assays.
Amanda M Casto, Meei-Li Huang, Hong Xie   +2 more
exaly   +3 more sources

Analysis of the Clinical Features of HSV-2 Encephalitis Confirmed by the mNGS Technique: Insights Derived from Seven Patient Studies. [PDF]

Infect Drug Resist
Shuhua Xie, Hong Zhang, Yuqing Xie, Fugan Liu, Songping Ye, Xianghong Liu,* Zhaohui Lai* Department of Neurology, Ganzhou People’s Hospital, Ganzhou, Jiangxi, 341000, People’s Republic of China*These authors contributed equally to
Xie S, Zhang H, Xie Y, Liu F, Ye S, Liu X, Lai Z.   +6 more
europepmc   +2 more sources

Epidemiological Characteristics of HSV-1 and HSV-2 in 177,599 Patients Based on PCR Testing in South Korea (2018–2022) [PDF]

Pathogens
HSV-1 is associated with oral lesions and non-sexual transmission; HSV-2 is primarily transmitted through sexual contact and causes genital infections.
Hyeong Ho Kim, Sung Hun Jang, Jeong Su Han, Jae-Sik Jeon, Jae Kyung Kim   +4 more
doaj   +2 more sources

Daily Acyclovir to Decrease Herpes Simplex Virus Type 2 (HSV-2) Transmission from HSV-2/HIV-1 Coinfected Persons: A Randomized Controlled Trial

Journal of Infectious Diseases, 2013
BACKGROUND: Daily suppressive therapy with valacyclovir reduces risk of sexual transmission of herpes simplex virus type 2 (HSV-2) in HSV-2-serodiscordant heterosexual couples by 48%.
Kenneth H Fife, Rhoda Morrow, David Coetzee   +2 more
exaly   +2 more sources

Analysis of HSV1/2 Infection Reveals an Association between HSV-2 Reactivation and Pregnancy [PDF]

Viruses
The herpes simplex viruses consist of the strains, HSV-1 and HSV-2, which are prevalent worldwide and lack a definitive cure. We aimed to explore the specific characteristics of HSV 1 and 2 infections, such as differences between gender assigned at birth,
Sara Dovrat, Adar Shabat, Anat Yahav-Dovrat, Zvia Soufiev, Ella Mendelson, Ela Kashi-Zagdoun, Galia Rahav   +6 more
doaj   +2 more sources

HSV-2- and HIV-1- permissive cell lines co-infected by HSV-2 and HIV-1 co-replicate HSV-2 and HIV-1 without production of HSV-2/HIV-1 pseudotype particles

Virology journal, 2007
Background Herpes simplex virus type 2 (HSV-2) is a major cofactor of human immunodeficiency virus type 1 (HIV-1) sexual acquisition and transmission.
Bouhlal Hicham, Jérôme LeGoff, Christophe Klein, Hakim Hocini, Muggeridge Martin, Maxime Lecerf, Si-Mohamed Ali, Ali Si-Mohamed, LeGoff Jérôme, Laurent Bélec, Bélec Laurent, Hicham Bouhlal, Klein Christophe, Martin Muggeridge, Hocini Hakim, Lecerf Maxime   +15 more
core   +4 more sources

Negative epidemiological association between HSV-1 and HSV-2 infections [PDF]

Heliyon, 2019
Objectives: Existing evidence on an epidemiological association between herpes simplex virus (HSV) type 1 and type 2 infections remains conflicting and inconclusive.
Gheyath K. Nasrallah, Soha R. Dargham, Laith J. Abu-Raddad   +2 more
doaj   +2 more sources

Seroprevalence of antibodies to herpes simplex virus 1 and 2 in patients with HIV positive from Ebonyi State, Nigeria: a cross-sectional study

BMJ Open, 2023
Objectives To assess the seroprevalence of herpes simplex virus (HSV) types 1 and 2 in patients infected with HIV in Nigeria.Design Cross-sectional design from January to June 2019.Setting Federal Teaching Hospital, Ebonyi State, Nigeria.Participants A ...
Euslar Nnenna Onu, Uchechukwu Onyeukwu Ekuma, Hawraa K Judi, Ogbonnaya Ogbu, Nworie Okoro, Gloria C Ajugwo, Sousan Akrami, Chukwudum S Okoli, Chioma Ngozi Anyanwu, Morteza Saki, Peter Anyigor Edeh   +10 more
doaj   +1 more source

HSV-2: in pursuit of a vaccine [PDF]

Journal of Clinical Investigation, 2011
Herpes simplex virus type 2 (HSV-2) is one of the most prevalent sexually transmitted infections worldwide. In addition to recurrent genital ulcers, HSV-2 causes neonatal herpes, and it is associated with a 3-fold increased risk for HIV acquisition. Although many HSV-2 vaccines have been studied in animal models, few have reached clinical trials, and ...
Christine, Johnston, David M, Koelle, Anna, Wald   +2 more
openaire   +2 more sources