Results 21 to 30 of about 112,416,099 (307)

Seroepidemiological study of herpes simplex virus types 1 and 2 in Brazil, Estonia, India, Morocco, and Sri Lanka [PDF]

, 2003
Background: The association between herpes simplex virus type 2 (HSV-2) and human immunodeficiency virus (HIV) and the development of HSV vaccines have increased interest in the study of HSV epidemiology.Objectives: To estimate the age and sex specific ...
Rbai, M, Robinson, NJ, de Oliveira, S Artimos, Gopal, R, Nygard-Kibur, M, Alami, K, Cowan, FM, Uuskula, A, Brown, DW, Mayaud, P, Sridharan, G, El Aouad, R, Ramalingam, S, de Oliveira, SA, Sunil-Chandra, NP, Faillace, T, French, RS   +16 more
core   +1 more source

Assessment of Herpes Simplex Virus Type 1 and 2 by IHC in Association with CD14 Antigen in Placental Tissues from Women with Miscarriage

Kurdistan Journal of Applied Research, 2018
Among many viral causes of miscarriage, maternal infections caused by herpes simplex virus type -1 (HSV-1) and Herpes simplex virus type-2 (HSV-2) infections are important causes.
Zainab A. Hamid, Solaf J. Ali, Ali Hattem Hussain   +2 more
doaj   +3 more sources

Immunization with Herpes Simplex Virus 2 (HSV-2) Genes plus Inactivated HSV-2 Is Highly Protective against Acute and Recurrent HSV-2 Disease [PDF]

Journal of Virology, 2011
ABSTRACTTo date, no vaccine that is safe and effective against herpes simplex virus 2 (HSV-2) disease has been licensed. In this study, we evaluated a DNA prime-formalin-inactivated-HSV-2 (FI-HSV2) boost vaccine approach in the guinea pig model of acute and recurrent HSV-2 genital disease.
Christopher S, Morello, Michael S, Levinson, Kimberly A, Kraynyak, Deborah H, Spector   +3 more
openaire   +2 more sources

Soroprevalência de anticorpos contra vírus herpes simples 1-2 no Brasil Seroprevalencia de anticuerpos contra virus herpes simples 1-2 en Brasil Seroprevalence of herpes simplex 1-2 antibodies in Brazil

Revista de Saúde Pública, 2010
OBJETIVO: Estimar a soroprevalência de anticorpos por vírus herpes simples (HSV-1 e HSV-2) e analisar fatores associados no Brasil. MÉTODOS: Estudo transversal realizado entre 1996 e 1997 em 1.090 indivíduos com idade entre um e 40 anos da população ...
Sue Ann Costa Clemens, Calil Kairalla Farhat   +1 more
doaj   +1 more source

Herpes Simplex Virus Mistyping due to HSV-1 × HSV-2 Interspecies Recombination in Viral Gene Encoding Glycoprotein B

Viruses, 2020
Human herpes simplex viruses (HSV) 1 and 2 are extremely common human pathogens with overlapping disease spectra. Infections due to HSV-1 and HSV-2 are distinguished in clinical settings using sequence-based “typing” assays.
Amanda M. Casto, Meei-Li W. Huang, Hong Xie, Keith R. Jerome, Anna Wald, Christine M. Johnston, Alexander L. Greninger   +6 more
doaj   +1 more source

A herpes simplex virus 2 (HSV-2) glycoprotein D-expressing nonreplicating dominant-negative HSV-2 virus vaccine is superior to a gD2 subunit vaccine against HSV-2 genital infection in guinea pigs. [PDF]

PLoS ONE, 2014
We recently constructed a novel non-replicating dominant-negative HSV-2 recombinant viral vaccine (CJ2-gD2) capable of expressing various HSV-2 antigens that are dominant targets of HSV-2-specific CD8 T-cell response.
Pengwei Zhang, Lining Xie, John W Balliet, Danilo R Casimiro, Feng Yao   +4 more
doaj   +1 more source

Risk factors for herpes simplex virus type 2 and HIV among women at high risk in northwestern Tanzania: preparing for an HSV-2 intervention trial. [PDF]

, 2007
OBJECTIVES: To determine prevalence of and risk factors for herpes simplex virus type 2 (HSV-2) and HIV among women being screened for a randomized, controlled trial of HSV suppressive therapy in northwestern Tanzania. METHODS: Two thousand seven hundred
Mugeye, Kokugonza, Hayes, Richard J, Balira, Rebecca, Knight, Louise, Ross, David, Changalucha, John, Weiss, Helen A, Baisley, Kathy, Watson-Jones, Deborah, Rusizoka, Mary, Everett, Dean   +10 more
core   +1 more source

Variant Analysis of the Thymidine Kinase and DNA Polymerase Genes of Herpes Simplex Virus in Korea: Frequency of Acyclovir Resistance Mutations

Viruses, 2023
The thymidine kinase (TK) and DNA polymerase (pol) genes of the herpes simplex viruses type 1 (HSV-1) and type 2 (HSV-2) are two important genes involved in antiviral resistance.
Jungwon Hyun, Su Kyung Lee, Ji Hyun Kim, Eun-Jung Cho, Han-Sung Kim, Jae-Seok Kim, Wonkeun Song, Hyun Soo Kim   +7 more
doaj   +1 more source

Virus-specific immune memory at peripheral sites of herpes simplex virus type 2 (HSV-2) infection in guinea pigs. [PDF]

PLoS ONE, 2014
Despite its importance in modulating HSV-2 pathogenesis, the nature of tissue-resident immune memory to HSV-2 is not completely understood. We used genital HSV-2 infection of guinea pigs to assess the type and location of HSV-specific memory cells at ...
Jingya Xia, Ronald L Veselenak, Summer R Gorder, Nigel Bourne, Gregg N Milligan   +4 more
doaj   +1 more source

Seroprevalence, predictors and estimated incidence of maternal and neonatal Herpes Simplex Virus Type 2 infection in semi-urban women in Kilifi, Kenya [PDF]

, 2011
Background: Herpes Simplex Virus type 2 (HSV-2) has public health importance as a leading cause of genital ulcers, a co-factor in HIV-1 acquisition and transmission and as a cause of neonatal herpes infections.
Awuondo Ken, Pauli N Amornkul, Nyiro Joyce U, Ngetsa, Caroline, Amornkul Pauli N, Amornkul, Pauli N., Wale, Steve, Caroline Ngetsa, James Nokes D, Price Matthew A, Elizabeth Bukusi, Price, Matthew A., Joyce U Nyiro, Ngetsa Caroline, Bukusi, Elizabeth Anne, Bukusi Elizabeth, Nokes, D. James, Awuondo, Ken, Wale Steve, Ken Awuondo, D James Nokes, Sanders Eduard J, Nyiro, Joyce U., Eduard J Sanders, Matthew A Price, Sanders, Eduard J., Steve Wale   +26 more
core   +2 more sources