Results 21 to 30 of about 80,157 (261)
Kurdistan Journal of Applied Research, 2018 Among many viral causes of miscarriage, maternal infections caused by herpes simplex virus type -1 (HSV-1) and Herpes simplex virus type-2 (HSV-2) infections are important causes.
Zainab A. Hamid +2 more
doaj +3 more sources
Revista de Saúde Pública, 2010 OBJETIVO: Estimar a soroprevalência de anticorpos por vírus herpes simples (HSV-1 e HSV-2) e analisar fatores associados no Brasil. MÉTODOS: Estudo transversal realizado entre 1996 e 1997 em 1.090 indivíduos com idade entre um e 40 anos da população ...
Sue Ann Costa Clemens +1 more
doaj +1 more source
Viruses, 2023 The thymidine kinase (TK) and DNA polymerase (pol) genes of the herpes simplex viruses type 1 (HSV-1) and type 2 (HSV-2) are two important genes involved in antiviral resistance.
Jungwon Hyun +7 more
doaj +1 more source
A herpes simplex virus 2 (HSV-2) glycoprotein D-expressing nonreplicating dominant-negative HSV-2 virus vaccine is superior to a gD2 subunit vaccine against HSV-2 genital infection in guinea pigs. [PDF]
PLoS ONE, 2014 We recently constructed a novel non-replicating dominant-negative HSV-2 recombinant viral vaccine (CJ2-gD2) capable of expressing various HSV-2 antigens that are dominant targets of HSV-2-specific CD8 T-cell response.
Pengwei Zhang +4 more
doaj +1 more source
Assessing the contribution of the herpes simplex virus DNA polymerase to spontaneous mutations
BMC Infectious Diseases, 2002 Background The thymidine kinase (tk) mutagenesis assay is often utilized to determine the frequency of herpes simplex virus (HSV) replication-mediated mutations. Using this assay, clinical and laboratory HSV-2 isolates were shown to have a 10- to 80-fold
Leary Jeffry J +8 more
doaj +1 more source
Fatal fulminant HSV-2 myocarditis: A complicated presentation [PDF]
International Journal of Infectious Diseases, 2022 Herpes simplex virus type 2 (HSV-2) infection is the leading cause of genital lesions. Infrequently HSV-2 primary infection can spread and involve other tissue and organs, however in immunocompetent individuals extra-genital complications are rare findings.
Daniele Colombo +7 more
openaire +3 more sources
Antibodies Are Required for Complete Vaccine-Induced Protection against Herpes Simplex Virus 2.
PLoS ONE, 2015 Herpes simplex virus 2 (HSV-2) 0ΔNLS is a live HSV-2 ICP0- mutant vaccine strain that is profoundly attenuated in vivo due to its interferon-hypersensitivity.
William P Halford +3 more
doaj +1 more source
PLoS ONE, 2010 Herpes simplex virus 1 (HSV-1) ICP0(-) mutants are interferon-sensitive, avirulent, and elicit protective immunity against HSV-1 (Virol J, 2006, 3:44).
William P Halford +2 more
doaj +1 more source
Disseminated HSV-2 presenting with relapsing encephalomyelitis [PDF]
Neurology Clinical Practice, 2016 A previously healthy 39-year-old woman presented with 3 weeks of progressive leg numbness. Examination showed mild bilateral iliopsoas weakness and patchy leg numbness. She was admitted, and spinal MRI revealed T2 enhancing thoracic lesions, nonenhancing cervical cord lesions (figure, A), and subtle pial and cauda equina enhancement (figure, B).
Clotilde, Hainline +6 more
openaire +2 more sources
Virus-specific immune memory at peripheral sites of herpes simplex virus type 2 (HSV-2) infection in guinea pigs. [PDF]
PLoS ONE, 2014 Despite its importance in modulating HSV-2 pathogenesis, the nature of tissue-resident immune memory to HSV-2 is not completely understood. We used genital HSV-2 infection of guinea pigs to assess the type and location of HSV-specific memory cells at ...
Jingya Xia +4 more
doaj +1 more source