Results 21 to 30 of about 95,433 (302)

HSV-2: in pursuit of a vaccine [PDF]

Journal of Clinical Investigation, 2011
Herpes simplex virus type 2 (HSV-2) is one of the most prevalent sexually transmitted infections worldwide. In addition to recurrent genital ulcers, HSV-2 causes neonatal herpes, and it is associated with a 3-fold increased risk for HIV acquisition. Although many HSV-2 vaccines have been studied in animal models, few have reached clinical trials, and ...
Christine, Johnston, David M, Koelle, Anna, Wald   +2 more
openaire   +2 more sources

Herpes Simplex Virus Mistyping due to HSV-1 × HSV-2 Interspecies Recombination in Viral Gene Encoding Glycoprotein B

Viruses, 2020
Human herpes simplex viruses (HSV) 1 and 2 are extremely common human pathogens with overlapping disease spectra. Infections due to HSV-1 and HSV-2 are distinguished in clinical settings using sequence-based “typing” assays.
Amanda M. Casto, Meei-Li W. Huang, Hong Xie, Keith R. Jerome, Anna Wald, Christine M. Johnston, Alexander L. Greninger   +6 more
doaj   +1 more source

Potential of mucoadhesive chitosan glutamate microparticles as microbicide carriers – antiherpes activity and penetration behavior across the human vaginal epithelium

Drug Delivery, 2021
Chitosan glutamate (gCS) spray-dried microparticles appear promising carriers to overcome challenges associated with vaginal microbicide delivery. This study aimed at elucidating the penetration and mucoadhesive behavior of developed gCS multiunit ...
Emilia Szymańska, Małgorzata Krzyżowska, Krzysztof Cal, Barbara Mikolaszek, Jakub Tomaszewski, Sławomir Wołczyński, Katarzyna Winnicka   +6 more
doaj   +1 more source

Assessment of Herpes Simplex Virus Type 1 and 2 by IHC in Association with CD14 Antigen in Placental Tissues from Women with Miscarriage

Kurdistan Journal of Applied Research, 2018
Among many viral causes of miscarriage, maternal infections caused by herpes simplex virus type -1 (HSV-1) and Herpes simplex virus type-2 (HSV-2) infections are important causes.
Zainab A. Hamid, Solaf J. Ali, Ali Hattem Hussain   +2 more
doaj   +3 more sources

Disseminated HSV-2 presenting with relapsing encephalomyelitis [PDF]

Neurology Clinical Practice, 2016
A previously healthy 39-year-old woman presented with 3 weeks of progressive leg numbness. Examination showed mild bilateral iliopsoas weakness and patchy leg numbness. She was admitted, and spinal MRI revealed T2 enhancing thoracic lesions, nonenhancing cervical cord lesions (figure, A), and subtle pial and cauda equina enhancement (figure, B).
Clotilde, Hainline, Dominique, Rosales, Purvi, Parikh, Eddie, Louie, Jonathan, Howard, Nina, Kim, Steven L, Galetta   +6 more
openaire   +2 more sources

Interaction between herpesvirus entry mediator and HSV-2 glycoproteins mediates HIV-1 entry of HSV-2-infected epithelial cells. [PDF]

, 2017
Herpes simplex virus type 2 (HSV-2) increases human immunodeficiency virus type 1 (HIV-1) acquisition and transmission via unclear mechanisms. Herpesvirus entry mediator (HVEM), an HSV-2 entry receptor, is highly expressed on HIV-1 target cells (CD4+ T ...
He, S, Hu, K, Hu, Q, Li, M, Luo, S, Xiao, J, Zhang, M   +6 more
core   +1 more source

HSV-2 sacral radiculitis (Elsberg syndrome)

Neurology, 2004
A self-limiting syndrome of acute urinary retention in combination with variable other signs of spinal cord dysfunction and CSF pleocytosis was described by Elsberg >70 years ago.1 In many instances, a viral etiology is found, and herpes simplex virus type 2 (HSV-2) reactivation from spinal ganglia is the most common associated infection.
Eberhardt, O, Küker, W, Dichgans, J, Weller, M   +3 more
openaire   +3 more sources

Global population-level association between herpes simplex virus 2 prevalence and HIV prevalence. [PDF]

, 2018
BACKGROUND: Our objective was to assess the population-level association between herpes simplex virus 2 (HSV-2) and HIV prevalence. METHODS: Reports of HSV-2 and HIV prevalence were systematically reviewed and synthesized following PRISMA guidelines ...
Abu-Raddad, Laith J, Chaabna, Karima, Heijnen, Marieke, Kouyoumjian, Silva P, Mumtaz, Ghina R, Omori, Ryosuke, Vickerman, Peter   +6 more
core   +3 more sources

Seroprevalence of herpes simplex virus type 1 and type 2 among the migrant workers in Qatar

Virology Journal, 2023
Background Limited data exists on herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) infections in migrant populations. This study investigated HSV-1 and HSV-2 seroprevalences and associations among craft and manual workers (CMWs) in Qatar who ...
Gheyath K. Nasrallah, Soha R. Dargham, Duaa W. Al-Sadeq, Fathima H. Amanullah, Farah M. Shurrab, Parveen B. Nizamuddin, Hiam Chemaitelly, Houssein H. Ayoub, Sami Abdeen, Ashraf Abdelkarim, Faisal Daraan, Ahmed Ismail, Nahid Mostafa, Mohamed Sahl, Jinan Suliman, Elias Tayar, Hasan Ali Kasem, Meynard J. A. Agsalog, Bassam K. Akkarathodiyil, Ayat A. Alkhalaf, Mohamed Morhaf M. H. Alakshar, Abdulsalam Ali A. H. Al-Qahtani, Monther H. A. Al-Shedifat, Anas Ansari, Ahmad Ali Ataalla, Sandeep Chougule, Abhilash K. K. V. Gopinathan, Feroz J. Poolakundan, Sanjay U. Ranbhise, Saed M. A. Saefan, Mohamed M. Thaivalappil, Abubacker S. Thoyalil, Inayath M. Umar, Einas Al Kuwari, Peter Coyle, Andrew Jeremijenko, Anvar Hassan Kaleeckal, Hanan F. Abdul Rahim, Hadi M. Yassine, Asmaa A. Al Thani, Odette Chaghoury, Mohamed Ghaith Al Kuwari, Elmoubasher Farag, Roberto Bertollini, Hamad Eid Al Romaihi, Abdullatif Al Khal, Mohamed H. Al-Thani, Laith J. Abu-Raddad   +47 more
doaj   +1 more source

Soroprevalência de anticorpos contra vírus herpes simples 1-2 no Brasil Seroprevalencia de anticuerpos contra virus herpes simples 1-2 en Brasil Seroprevalence of herpes simplex 1-2 antibodies in Brazil

Revista de Saúde Pública, 2010
OBJETIVO: Estimar a soroprevalência de anticorpos por vírus herpes simples (HSV-1 e HSV-2) e analisar fatores associados no Brasil. MÉTODOS: Estudo transversal realizado entre 1996 e 1997 em 1.090 indivíduos com idade entre um e 40 anos da população ...
Sue Ann Costa Clemens, Calil Kairalla Farhat   +1 more
doaj   +1 more source