Results 61 to 70 of about 21,325,054 (309)

HSV-1 inflammasome activation in THP-1 cells is dependent on NLRP3, ASC, and caspase-1.

, 2020
A. THP-1 cells were stimulated overnight with PMA (100 ng/mL) and then incubated with HSV-1, nigericin and LPS (Ng+LPS), or media, as outlined in Materials and Methods, for 24 hours.
Andrew H. Karaba (2419798), Guido Massaccesi (8496237), Sara Botto (210516), Alexis Figueroa (8496234), Andrea L. Cox (8496243), Victor R. DeFilippis (8496240)   +5 more
core   +1 more source

The epidemiology of HIV and HSV-2 infections among women participating in microbicide and vaccine feasibility studies in Northern Tanzania. [PDF]

, 2013
OBJECTIVES: To prepare for future HIV prevention trials, we conducted prospective cohort studies among women working in food and recreational facilities in northern Tanzania.
Watson-Jones Deborah, Joseph Chilongani, Mongi Aika, Watson-Jones, Deborah, John Changalucha (243873), Hashim, Ramadhan, Tony Ao (434475), Hayes Richard, Saidi H. Kapiga (124370), Saidi H Kapiga, Aika Mongi, Aura Andreasen, Deborah Watson-Jones, Aika Mongi (434477), Kathy Baisley (132119), Ramadhan Hashim (148699), Deborah Watson-Jones (230055), Chilongani Joseph, Baisley, Kathy, Francis, Suzanna, Changalucha John, Fiona M. Ewings (309182), Hayes, Richard, Richard Hayes, Chilongani, Joseph, Kathy Baisley, Suzanna Francis, Richard Hayes (32740), Changalucha, John, Aura Andreasen (247728), Joseph Chilongani (434476), Kapiga, Saidi H, Ao, Tony, Mongi, Aika, Andreasen, Aura, Ramadhan Hashim, Andreasen Aura, John Changalucha, Hashim Ramadhan, Francis Suzanna, Ao Tony, Tony Ao, Baisley Kathy, Fiona M Ewings, Ewings Fiona M., Suzanna Francis (434478), Kapiga Saidi H., Ewings, Fiona M   +47 more
core   +1 more source

NIBV Induces Incomplete Autophagy via AMPK‐TFEB, Causing Kidney Injury in Chicks

Advanced Science, EarlyView.
This study reveals that NIBV can inhibit the nuclear translocation of TFEB by suppressing the expression of AMPK, leading to the blockade of autophagolysosomal functions, in turn increasing NIBV replication and triggering severe kidney injury in chicks.
Cheng Huang, Yizhou Zeng, Yunfeng Chen, Zhengqing Li, Salma Mbarouk Omar, Shengwei Zhong, Ping Liu, Zhanhong Zheng, Gaofeng Cai, Xiaona Gao, Xiaoquan Guo   +10 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Computer Vision Enables Monitoring and Kinetic Analysis of Structurally Diverse Carbon Monoxide Surrogates

Angewandte Chemie, EarlyView.
A non‐contact computer vision method enables monitoring and quantitative comparison of vessel‐specific CO release kinetics from structurally diverse surrogates in two‐chamber COware reactors, revealing that surrogate reactivity scores correlate with carbonylation reaction outcomes.
Kristin Donnachie, Ciaran Griffin, Morven L. Gray, Timothy J. D. McCabe, Marc Reid   +4 more
wiley   +2 more sources

Herpes simplex virus infections among rural residents in eastern China

BMC Infectious Diseases, 2011
Background Herpes simplex virus (HSV) has two types: HSV-1 and HSV-2. Both infect epithelial cells and establish latent infections in neurons causing an infection that persists for life. Information on age- and gender-specific seroprevalence of HSV-1 and
Chen Li, Su Meifang, Feng Jifu, He Na, Lin Haijiang, Gao Meiyang   +5 more
doaj   +1 more source

HSV-1 activates inflammasomes in primary human macrophages.

, 2020
A and B. Primary human MDMs cultured without (M0 A) or with IFNγ (M1 B) were incubated with HSV-1 or media for 24 hours. Cell culture supernatants were collected and assayed for IL-18 (B represents the combination of two experiments).
Andrew H. Karaba (2419798), Guido Massaccesi (8496237), Sara Botto (210516), Alexis Figueroa (8496234), Andrea L. Cox (8496243), Victor R. DeFilippis (8496240)   +5 more
core   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

Herpes simplex virus type 1 and 2 in mucocutaneous infections

Journal of Oral Microbiology, 2017
Herpes simplex virus (HSV) type 1 and 2 are both known to cause mucosal and skin infections. HSV-1 is regarded as the main virus type in the orofacial region, whereas HSV-2 is mainly associated with genital infections.
Hannamari Välimaa
doaj   +1 more source

HSV-1 L-particles interfere with the H-particle-induced IFNα response by human PBMC in a dose dependent manner.

, 2021
(A) Coomassie blue staining of density gradient purified HSV-1 L- and H-particles. Arrow indicates position of the VP5 major capsid protein that is present in H-particles but absent from L-particles.
Cliff Van Waesberghe (11768086), Jonas L. Delva (11768083), Barbara G. Klupp (8635983), Thomas C. Mettenleiter (6849764), Herman W. Favoreel (7607057)   +4 more
core   +1 more source