Results 71 to 80 of about 84,858 (261)

What Makes an “Ideal” Cell Line for Recombinant Adeno‐Associated Virus Production?

Biotechnology and Bioengineering, EarlyView.
Several host cell types have been used to produce rAAVs to date. Cell line‐specific traits that are beneficial in the context of rAAV manufacturing are reviewed here, with the goal of developing a consensus on the ‘ideal’ characteristics that an rAAV production host should possess (created with Biorender.com).
James Conheady, Nicholas Donohue, Alexandra Bogdanovic, Sharon Davin, Brian Glennon, Niall Barron, C. Mark Smales   +6 more
wiley   +1 more source

A case series of necrotizing periodontal diseases in hospitalized patients: What hasn't been said yet?

Clinical Advances in Periodontics, EarlyView.
Abstract Background Necrotizing periodontal diseases (NPDs) are uncommon and severe inflammatory conditions characterized by tissue necrosis, painful ulceration, and rapid clinical progression, frequently associated with systemic immunosuppression. Limited data exist regarding their clinical presentation and management in hospital settings.
Osmaria Letthycia Carvalho Leal, Fernanda Bortolotto, Mariana Cristina Manoel, Gabriela Silveira de Araújo, Ana Carolina Fragoso Motta, Leandro Dorigan de Macedo, Lara Maria Alencar Ramos Innocentini, Joab Cabral Ramos, Isabel Schausltz Pereira Faustino   +8 more
wiley   +1 more source

Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2

Frontiers in Microbiology, 2019
Omeprazole was shown to improve the anti-cancer effects of the nucleoside analogue 5-fluorouracil. Here, we combined omeprazole with the antiviral nucleoside analogues ribavirin and acyclovir.
Martin Michaelis, Malte C. Kleinschmidt, Denisa Bojkova, Holger F. Rabenau, Mark N. Wass, Jindrich Cinatl Jr.   +5 more
doaj   +1 more source

Opsoclonus in Pediatric Patients: Differential Diagnosis and a Practical Approach to Evaluation

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Opsoclonus is an ocular dyskinesia characterized by involuntary, arrhythmic, multidirectional saccades. In pediatrics, opsoclonus is most commonly attributed to the rare neuroinflammatory disorder opsoclonus‐myoclonus‐ataxia syndrome (OMAS), typically considered a paraneoplastic syndrome associated with neural crest tumors. However, opsoclonus
Aubrey C. Reed, Supreet S. Randhawa, Jason H. Peragallo, Prabhumallikarjun Patil, Grace Gombolay, Varun Kannan   +5 more
wiley   +1 more source

Aqueous Supercapacitor with Wide‐Temperature Operability and over 100,000 Cycles Enabled by Water‐in‐Salt Electrolyte

ChemSusChem, Volume 18, Issue 6, March 15, 2025.
This study presents a symmetric supercapacitor with activated carbon electrodes and a “water‐in‐salt” electrolyte (WiSE) based on lithium perchlorate, offering over 100,000 cycles with over 90 % capacity retention. The supercapacitor operates efficiently from −20 to 80 °C, enhancing performance, stability, and all‐season operability.
Zahid Ali Zafar, Radim Weisser, Ghulam Abbas, Martin Silhavik, Prabhat Kumar, Jiří Červenka   +5 more
wiley   +1 more source

Protection of Mice by an Apathogenic Strain of HSV-1 Against Lethal Infection by a Pathogenic Strain of HSV-1

Journal of General Virology, 1981
DBA/2 and C57BL/6 mice were infected intraperitoneally with two different strains of herpes simplex virus type 1, HSV-1 ANG and HSV-1 WAL. Unlike HSV-1 WAL, HSV-1 ANG was apathogenic by this mode of infection. Furthermore, infection with HSV-1 ANG protected mice of both inbred strains against infections with lethal doses of pathogenic HSV-1 WAL.
C H, Schröeder, H, Engler, H, Kirchner
openaire   +2 more sources

Drying‐Driven Microstructural Reorganization as a Key Origin of Rate Limitation in Multi‐Walled Carbon Nanotube‐Based Thick Electrodes for Lithium‐Ion Batteries

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This study shows drying‐driven microstructural reorganization as a key origin of rate limitations in multi‐walled carbon nanotubes (MWCNT)‐based thick electrodes. By decoupling transport properties, the work reveals that rapid evaporation can amplify thickness‐dependent CNT agglomeration, generating coupled electronic and ionic bottlenecks. Importantly,
So Min Gong, Seung Woo Song, Yonghwan Kim, Jiyoon Yoon, Jun Hyun Kang, Yeonsu Jung, Taehoon Kim, Seung Jae Yang, Jae Ho Kim   +8 more
wiley   +1 more source

Amentoflavone Inhibits HSV-1 and ACV-Resistant Strain Infection by Suppressing Viral Early Infection

Viruses, 2019
Infection of Herpes simplex virus 1 (HSV-1) induces severe clinical disorders, such as herpes simplex encephalitis and keratitis. Acyclovir (ACV) is the current therapeutic drug against viral infection and ACV-resistant strains have gradually emerged ...
Feng Li, Xiaowei Song, Guifeng Su, Yiliang Wang, Zhaoyang Wang, Jiaoyan Jia, Shurong Qing, Lianzhou Huang, Yuan Wang, Kai Zheng, Yifei Wang   +10 more
doaj   +1 more source

The effect of anti‐seizure medications on exposure to statins: A systematic review and meta‐analysis

Epileptic Disorders, EarlyView.
Abstract Objectives Antiseizure medications (ASMs) can reduce the efficacy of statin treatment, partly due to reduction in statin concentrations. In this systematic review and network meta‐analysis (NMA), we compared the effects of ASMs and the prototypical enzyme inducer rifampin on statin exposure.
Sharon Valiyev Huino, Hagar Cohen, Bruria Hirsh Raccah, Tomer Ben‐Shushan, Ilan Matok, Sara Eyal   +5 more
wiley   +1 more source

“Nature's Polymer Reimagined: Conventional and Green Routes to Pectin, Its Bioactive Promise and Industrial Applications”

Food Chemistry International, EarlyView.
Pectin, a versatile natural polymer, is extracted through conventional and emerging green extraction methods, offering multifunctional bioactive properties useful in food, pharmaceutical, and environmental applications. ABSTRACT Pectin, a molecular tapestry woven from diverse polysaccharides, holds a pivotal role across food, pharmaceutical, and ...
Afra Anika Rafique, Aunwesha Sahani, Md Morsaline Billah, Kazi Mohammed Didarul Islam   +3 more
wiley   +1 more source