Results 31 to 40 of about 29,786,765 (312)

Understanding HSV‐1 entry glycoproteins [PDF]

open access: yesReviews in Medical Virology, 2007
AbstractHerpes Simplex Virus‐1 is a common infectious agent, but the precise detail of entry and infection of cells has only now begun to be clarified. Four viral surface glycoproteins (gB, gD, gH and gL) are required. This review summarises the known structure and function of each of these essential viral envelope glycoproteins, and explores what is ...
Adi, Reske   +4 more
openaire   +2 more sources

Correlates of HIV-1 genital shedding in Tanzanian women. [PDF]

open access: yes, 2011
BACKGROUND: Understanding the correlates of HIV shedding is important to inform strategies to reduce HIV infectiousness. We examined correlates of genital HIV-1 RNA in women who were seropositive for both herpes simplex virus (HSV)-2 and HIV-1 and who ...
Clare Tanton   +35 more
core   +1 more source

Soroprevalência de anticorpos contra vírus herpes simples 1-2 no Brasil Seroprevalencia de anticuerpos contra virus herpes simples 1-2 en Brasil Seroprevalence of herpes simplex 1-2 antibodies in Brazil

open access: yesRevista de Saúde Pública, 2010
OBJETIVO: Estimar a soroprevalência de anticorpos por vírus herpes simples (HSV-1 e HSV-2) e analisar fatores associados no Brasil. MÉTODOS: Estudo transversal realizado entre 1996 e 1997 em 1.090 indivíduos com idade entre um e 40 anos da população ...
Sue Ann Costa Clemens   +1 more
doaj   +1 more source

Local CD4 and CD8 T-cell reactivity to HSV-1 antigens documents broad viral protein expression and immune competence in latently infected human trigeminal ganglia. [PDF]

open access: yesPLoS Pathogens, 2013
Herpes simplex virus type 1 (HSV-1) infection results in lifelong chronic infection of trigeminal ganglion (TG) neurons, also referred to as neuronal HSV-1 latency, with periodic reactivation leading to recrudescent herpetic disease in some persons.
Monique van Velzen   +5 more
doaj   +1 more source

HSV-1 not only in human vestibular ganglia but also in the vestibular labyrinth [PDF]

open access: yes, 2001
Reactivation of herpes simplex virus type 1 (HSV-1) in the vestibular ganglion (VG) is the suspected cause of vestibular neuritis (VN). Recent studies reported the presence of HSV-1 DNA not only in human VGs but also in vestibular nuclei, a finding that ...
Mascolo, Andrea   +4 more
core   +1 more source

HSV-1 infection upregulates PAD expression in human fibroblasts.

open access: yes, 2023
(A) mRNA expression levels of PADI isoforms by RT-qPCR of HSV-1-infected (8 and 16 hpi) vs uninfected (mock) HFFs were normalized to the housekeeping gene glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and expressed as mean fold change ± SEM over mock ...
Leonard Barasa (16318086)   +17 more
core   +1 more source

HSV-2- and HIV-1- permissive cell lines co-infected by HSV-2 and HIV-1 co-replicate HSV-2 and HIV-1 without production of HSV-2/HIV-1 pseudotype particles

open access: yesVirology Journal, 2007
Background Herpes simplex virus type 2 (HSV-2) is a major cofactor of human immunodeficiency virus type 1 (HIV-1) sexual acquisition and transmission.
Bélec Laurent   +7 more
doaj   +1 more source

The HSV-1 transcription factor ICP4 confers liquid-like properties to viral replication compartments [PDF]

open access: yes, 2023
openIl virus Herpes Simplex di tipo 1 (HSV-1) forma progenie nel nucleo all'interno dei compartimenti di replicazione virale (VRC), dove si verificano l'espressione genica virale, la replicazione del DNA e l’assemblaggio.
RUGGERO, ANGELA
core  

HSV neutralization by the microbicidal candidate C5A. [PDF]

open access: yesPLoS ONE, 2011
Genital herpes is a major risk factor in acquiring human immunodeficiency virus type-1 (HIV-1) infection and is caused by both Herpes Simplex virus type 1 (HSV-1) and HSV-2.
Lot de Witte   +6 more
doaj   +1 more source

De Novo synthesis of VP16 coordinates the exit from HSV latency in vivo [PDF]

open access: yes, 2009
The mechanism controlling the exit from herpes simplex virus latency (HSV) is of central importance to recurrent disease and transmission of infection, yet interactions between host and viral functions that govern this process remain unclear. The cascade
Sawtell, N.M.   +5 more
core   +1 more source

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