Results 31 to 40 of about 81,374 (218)

Herpes Simplex Virus 1 and 2 Infections during Differentiation of Human Cortical Neurons

Viruses, 2021
Herpes simplex virus 1 (HSV-1) and 2 (HSV-2) can infect the central nervous system (CNS) with dire consequences; in children and adults, HSV-1 may cause focal encephalitis, while HSV-2 causes meningitis.
Petra Bergström, Edward Trybala, Charlotta E. Eriksson, Maria Johansson, Tugce Munise Satir, Sibylle Widéhn, Stefanie Fruhwürth, Wojciech Michno, Faisal Hayat Nazir, Jörg Hanrieder, Soren Riis Paludan, Lotta Agholme, Henrik Zetterberg, Tomas Bergström   +13 more
doaj   +1 more source

Atypical MRI Findings in HSV-1 Encephalitis. [PDF]

Intern Med
Matsushita S, Ariyoshi S, Horitani R.
europepmc   +4 more sources

Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez, Monica Ferrer Socorro, Kathryn Yang, Nicole Battaglia, Zainab Zaman, Mariko Bennett, Adeline Vanderver, Pui Y. Lee, Lauren A. Henderson, Milena M. Andzelm, Darius Ebrahimi‐Fakhari   +10 more
wiley   +1 more source

Left out but not Forgotten: Should Closer Attention be Paid to Coinfection with Herpes Simplex Virus Type 1 and HIV?

Canadian Journal of Infectious Diseases and Medical Microbiology, 2009
Herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) are among the most common coinfections seen in individuals infected with HIV-1. Most research on HSV-HIV coinfection has focused on HSV-2, and in particular, on its impact on HIV transmission.
Darrell H S Tan, Rupert Kaul, Sharon Walsmley   +2 more
doaj   +1 more source

The Case of a 40‐Year‐Old Man With New‐Onset Status Epilepticus in the Setting of HIV Infection

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 40‐year‐old man from Andhra Pradesh in India, while on regular antiretroviral treatment (ART) for long‐standing HIV infection presented with a 1‐day history of new‐onset status epilepticus. CT and MRI brain showed multifocal cerebral ring lesions, some of which demonstrated characteristic ‘hole‐with‐a‐dot’ sign.
Vadde Akhil, Ramachandiran Nandhagopal
wiley   +1 more source

IFI16 Restricts HSV-1 Replication by Accumulating on the HSV-1 Genome, Repressing HSV-1 Gene Expression, and Directly or Indirectly Modulating Histone Modifications

PLoS Pathogens, 2014
Interferon-γ inducible factor 16 (IFI16) is a multifunctional nuclear protein involved in transcriptional regulation, induction of interferon-β (IFN-β), and activation of the inflammasome response. It interacts with the sugar-phosphate backbone of dsDNA and modulates viral and cellular transcription through largely undetermined mechanisms.
Karen E Johnson, Virginie Bottero, Stephanie Flaherty, Sujoy Dutta, Vivek Vikram Singh, Bala Chandran   +5 more
openaire   +4 more sources

Portable Molecularly Imprinted Polymer Sensor for Rapid Swab‐Based Detection of Norovirus

Advanced Healthcare Materials, EarlyView.
This work reports a rapid, portable smartphone‐based sensor capable of detecting four norovirus genotypes from swab samples within 15 min. Sensor selectivity was validated through evaluation against four common live viruses. The swab‐based sampling process enabled simple sample preparation combined with the compact detection system, supporting use of ...
Amy Dann, Pankaj Singla, Minji Kim, Sloane Stoufer, Clare Thomas, Robert D. Crapnell, Craig E. Banks, Jake McClements, Shayan Seyedin, Mark Geoghegan, Samuel T. Jones, Christopher F. Blanford, Matthew D. Moore, Marloes Peeters   +13 more
wiley   +1 more source

تغییرات اپیدمیولوژیHSV-1: اثر آن بر روی وقوع هرپس چشمی [PDF]

Archives of Razi Institute, 2016
HSV-1 شیوع گسترده­ای در بین جمعیت­های انسانی دارد و نتیجه آن ایجاد طیف گسترده­ای از عفونت­ها و بیماری­ها می­باشد.اگرچه،HSV-2  عامل اصلی هرپس جنسی می­باشد، هرپس جنسی ناشی از HSV-1 نیز در حال افزایش می­باشد. این مقاله تغییرات اپیدمیولوژیکی HSV-1 را که شامل
بهمن عابدی کیاسری, زهره زارع توران پشتی   +1 more
doaj   +1 more source

Combination of 3D and 2D Small and Wide Angle X‐Ray Scattering Imaging Reveals Diminished Bone Quality in the Superior Human Femoral Neck Cortex

Advanced Materials, EarlyView.
Combined 2D and 3D X‐ray scattering imaging is used to analyse nanostructural properties in the inferior and superior cortex of 78 human femoral necks from 44 donors. The methodology allows for increased interpretation of nanostructure in a statistically relevant dataset, revealing nanostructural differences in anatomical locations critical to clinical
Torne Tänzer, Tatiana Kochetkova, Arthur Baroni, Mathieu Simon, Mads Carlsen, Santiago Fernandez Bordin, Manuel Guizar‐Sicairos, Philippe Zysset, Marianne Liebi   +8 more
wiley   +1 more source

Development of a high specificity typing method for the detection of herpes simplex virus

Frontiers in Bioengineering and Biotechnology, 2022
Herpes disease is caused by Herpes simplex virus (HSV). It has become one of the global health problems. This paper reports a method for HSV type testing. First specific primers sequence for HSV-1 and HSV-2 were selected, designed, and synthesized. Then,
Zhu Chen, Kaixuan Zhao, Boyu Tan, Zengrui Tong, Ziyu He, Xiaofang Luo, Lei Cai, Hanming Wang, Polly H. M. Leung, Franklin Wang-Ngai Chow, Hui Chen, Yan Deng   +11 more
doaj   +1 more source