Results 31 to 40 of about 21,325,054 (309)

Understanding HSV‐1 entry glycoproteins [PDF]

open access: yesReviews in Medical Virology, 2007
AbstractHerpes Simplex Virus‐1 is a common infectious agent, but the precise detail of entry and infection of cells has only now begun to be clarified. Four viral surface glycoproteins (gB, gD, gH and gL) are required. This review summarises the known structure and function of each of these essential viral envelope glycoproteins, and explores what is ...
Adi, Reske   +4 more
openaire   +2 more sources

Correlates of HIV-1 genital shedding in Tanzanian women. [PDF]

open access: yes, 2011
BACKGROUND: Understanding the correlates of HIV shedding is important to inform strategies to reduce HIV infectiousness. We examined correlates of genital HIV-1 RNA in women who were seropositive for both herpes simplex virus (HSV)-2 and HIV-1 and who ...
Clare Tanton   +35 more
core   +1 more source

HSV-1 not only in human vestibular ganglia but also in the vestibular labyrinth [PDF]

open access: yes, 2001
Reactivation of herpes simplex virus type 1 (HSV-1) in the vestibular ganglion (VG) is the suspected cause of vestibular neuritis (VN). Recent studies reported the presence of HSV-1 DNA not only in human VGs but also in vestibular nuclei, a finding that ...
Mascolo, Andrea   +4 more
core   +1 more source

HSV-1 infection upregulates PAD expression in human fibroblasts.

open access: yes, 2023
(A) mRNA expression levels of PADI isoforms by RT-qPCR of HSV-1-infected (8 and 16 hpi) vs uninfected (mock) HFFs were normalized to the housekeeping gene glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and expressed as mean fold change ± SEM over mock ...
Leonard Barasa (16318086)   +17 more
core   +1 more source

The HSV-1 transcription factor ICP4 confers liquid-like properties to viral replication compartments [PDF]

open access: yes, 2023
openIl virus Herpes Simplex di tipo 1 (HSV-1) forma progenie nel nucleo all'interno dei compartimenti di replicazione virale (VRC), dove si verificano l'espressione genica virale, la replicazione del DNA e l’assemblaggio.
RUGGERO, ANGELA
core  

De Novo synthesis of VP16 coordinates the exit from HSV latency in vivo [PDF]

open access: yes, 2009
The mechanism controlling the exit from herpes simplex virus latency (HSV) is of central importance to recurrent disease and transmission of infection, yet interactions between host and viral functions that govern this process remain unclear. The cascade
Sawtell, N.M.   +5 more
core   +1 more source

Seroepidemiological study of herpes simplex virus types 1 and 2 in Brazil, Estonia, India, Morocco, and Sri Lanka

open access: yes, 2003
Background: The association between herpes simplex virus type 2 (HSV-2) and human immunodeficiency virus (HIV) and the development of HSV vaccines have increased interest in the study of HSV epidemiology.Objectives: To estimate the age and sex specific ...
Rbai, M   +16 more
core   +1 more source

Anti-HSV-1 CRISPR gRNAs are ineffective in targeting quiescent HSV-1 but do abrogate replication of reactivated HSV-1.

open access: yes, 2016
a) MRC5 cells exogenously expressing Cas9 were infected with quiescent HSV-1-eGFP. Anti-HSV-1 gRNAs were introduced into the MRC5-Cas9 cells via lentiviral transduction and cells were subsequently superinfected with HCMV to reactivate latent HSV-1.
Anita C. Schürch (173257)   +9 more
core   +1 more source

HSV-1 infection induces IL-1β expression and secretion.

open access: yes, 2020
(A–K) TPA-differentiated THP-1 macrophages were treated with 2 μM Nigericin for 2 h, and infected with HSV-1 at MOI = 0.1, 0.2, 0.4 and 0.8 for 8 h (A, C, E and G), infected with HSV-1 at MOI = 0.8 for 2, 4, 6 and 8 h (B, D, F and H), or transfected with
Weijie Chen (1321836)   +16 more
core   +1 more source

DataSheet1_Effective Search of Triterpenes with Anti-HSV-1 Activity Using a Classification Model by Logistic Regression.pdf

open access: yes, 2021
Natural products are an excellent source of skeletons for medicinal seeds. Triterpenes and saponins are representative natural products that exhibit anti-herpes simplex virus type 1 (HSV-1) activity.
Keiko Ogawa (1796347)   +5 more
core   +1 more source

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