Results 1 to 10 of about 438,323 (304)

Broad-spectrum antiviral activity of ebselen [PDF]

Scientific Reports
Broad-spectrum antivirals are essential for pandemic preparedness, helping reduce mortality and mitigate social disruption. Ebselen, a synthetic organoselenium compound, is under investigation for treating various conditions, including viral infections ...
Kunlakanya Jitobaom, Usa Boonyuen, Chompunuch Boonarkart, Thanyaporn Sirihongthong, Prasert Auewarakul   +4 more
doaj   +2 more sources

Reactive oxygen species promotion drives auranofin’s antiviral activity against hepatitis E virus [PDF]

Journal of Virology
Hepatitis E virus (HEV) causes roughly 20 million yearly global infections and is associated with chronic hepatitis, neurological sequelae, and pregnancy-related adverse outcomes that require antiviral intervention.
Kateland Tiller, S. Tyler Williams, Bo Wang, Debin Tian, Xiang-Jin Meng, James Weger-Lucarelli   +5 more
doaj   +2 more sources

Antiviral Drug Research Proposal Activity

Journal of Microbiology & Biology Education, 2011
The development of antiviral drugs provides an excellent example of how basic and clinical research must be used together in order to achieve the final goal of treating disease.
Lisa Injaian, Ann C. Smith, Jennifer German Shipley, Gili Marbach-Ad, Brenda Fredericksen   +4 more
doaj   +3 more sources

Phosphorylation of Shiftless by casein kinase 1 δ/ε is required for its antiviral activity [PDF]

Journal of Virology
Shiftless (SHFL) is a host antiviral factor that inhibits the viral −1 programmed ribosomal frameshifting (−1PRF). How the antiviral activity of SHFL is regulated is not known. Here, we report that the phosphorylation of SHFL by the casein kinase 1 delta
Yongle Wang, Shaozu Fu, Xinlu Wang, Guangxia Gao   +3 more
doaj   +2 more sources

The Antiviral Activity of Polyphenols. [PDF]

Mol Nutr Food Res
ABSTRACTPolyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a wide range of employment, from food production to medical usages.
Burkard M, Piotrowsky A, Leischner C, Detert K, Venturelli S, Marongiu L.   +5 more
europepmc   +3 more sources

The vitamin D receptor agonist EB1089 can exert its antiviral activity independently of the vitamin D receptor.

PLoS ONE, 2023
Vitamin D has been shown to have antiviral activity in a number of different systems. However, few studies have investigated whether the antiviral activity is exerted through the vitamin D receptor (VDR).
Janejira Jaratsittisin, Wannapa Sornjai, Thanathom Chailangkarn, Anan Jongkaewwattana, Duncan R Smith   +4 more
doaj   +1 more source

Antiviral activity of berberine [PDF]

Archives of Virology, 2020
AbstractPlants are a rich source of new antiviral, pharmacologically active agents. The naturally occurring plant alkaloid berberine (BBR) is one of the phytochemicals with a broad range of biological activity, including anticancer, anti-inflammatory and antiviral activity.
Alicja Warowicka, Robert Nawrot, Anna Goździcka-Józefiak   +2 more
openaire   +2 more sources

Antiviral activities of flavonoids

Biomedicine & Pharmacotherapy, 2021
Flavonoids are natural phytochemicals known for their antiviral activity. The flavonoids acts at different stages of viral infection, such as viral entrance, replication and translation of proteins. Viruses cause various diseases such as SARS, Hepatitis, AIDS, Flu, Herpes, etc.
Badshah, Syed Lal, Faisal, Shah, Muhammad, Akhtar, Poulson, Benjamin Gabriel, Emwas, Abdul-Hamid M., Jaremko, Mariusz   +5 more
openaire   +3 more sources

MxA: a broadly acting effector of interferon-induced human innate immunity

Visualized Cancer Medicine, 2022
The Human MxA protein belongs to the dynamin superfamily of large GTPases and plays a vital role in human immunity against a broad spectrum of viruses. Evasion from MxA restriction accounts for the zoonotic transmission of many pathogenic viruses.
Liao Shuang, Gao Song
doaj   +1 more source

Antioxidant Capacity and Antimicrobial Activity of Commercial Samples of Guava Leaves (\u3cem\u3ePsidium guajava\u3c/em\u3e) [PDF]

, 2020
Psidium guajava is a small tree native to South and Central America. Guava leaves have traditionally been used for treating different illnesses. These benefits can be attributed to phenolics and flavonoids produced by guava.
Alsaidi, Sahar, Bonnaire, Thierry, Cornejal, Nadjet, Cruz Rodriguez, Gearoff, Cruz, Victor, Fernandez Romero, Jose, Gomez Ramirez, Aned, Koroch, Adolfina, Melo, Claudia, Priano, Christine, Sorel, Victor, Zydowsky, Thomas M   +11 more
core   +2 more sources