Anti–SARS‐CoV‐2 Repurposing Drug Database: Clinical Pharmacology Considerations
CPT: Pharmacometrics & Systems Pharmacology, 2021 A critical step to evaluate the potential in vivo antiviral activity of a drug is to connect the in vivo exposure to its in vitro antiviral activity. The Anti–SARS‐CoV‐2 Repurposing Drug Database is a database that includes both in vitro anti–SARS‐CoV‐2 ...
Xinyuan Zhang +13 more
doaj +1 more source
Poly(ADP-ribose) potentiates ZAP antiviral activity.
PLoS Pathogens, 2022 Zinc-finger antiviral protein (ZAP), also known as poly(ADP-ribose) polymerase 13 (PARP13), is an antiviral factor that selectively targets viral RNA for degradation.
Guangai Xue +10 more
doaj +1 more source
Luminescent polyelectrolytes with antiviral activity
Russian chemical bulletin = Izvestiia Akademii nauk. Seriia khimicheskaia, 2022 Radical polymerization was used to synthesize and characterize (co)polymers with sodium styrenesulfonate (NaSS), 4-methacryloylamidosalicylic acid (MASA), and N-vinylpyrrolidone, which have a low cytotoxicity and a high antiviral activity against the ...
E. F. Panarin +7 more
semanticscholar +1 more source
Potential antiviral activity of eleutherine, isoeleutherine, eleuthinone and elecanacine compounds in Eleutherine palmifolia (L.) Merr against NSP3 SARS-COV-2: in silico study [PDF]
, 2023 Eleutherine, isoeleutherine, eleuthinone and elecanacine are secondary metabolites of Dayak onion (Eleutherine palmifolia (L.) Merr) belonging to the naphtoquinone group and considered to have antiviral activity by inhibiting HIV replication.
Nafisa, Belia Bima +3 more
core +1 more source
Antiviral efficacy of nanomaterial-treated textiles in real-life like exposure conditions
Heliyon, 2023 Due to the growing interest towards reducing the number of potentially infectious agents on critical high-touch surfaces, the popularity of antimicrobially and antivirally active surfaces, including textiles, has increased.
Alexandra Nefedova +7 more
doaj +1 more source
Antiviral Activity of Ribosome-Inactivating Proteins
Toxins, 2021 Ribosome-inactivating proteins (RIPs) are rRNA N-glycosylases from plants (EC 3.2.2.22) that inactivate ribosomes thus inhibiting protein synthesis. The antiviral properties of RIPs have been investigated for more than four decades.
Lucía Citores +2 more
doaj +1 more source
FAM134B Restricts African Swine Fever Virus Capsid Assembly via Reticulophagy and Its Antiviral Activity is Antagonized by the Viral Virulence‐Associated Factor pMGF300‐2R [PDF]
Advanced Science, EarlyView.ABSTRACT African swine fever (ASF), caused by African swine fever virus (ASFV), is a devastating viral disease in domestic pigs and wild boar. ASFV is a large DNA virus whose capsid assembly takes place within perinuclear viral factories (VFs). Accumulating evidence has demonstrated that reticulophagy confers antiviral activity against multiple RNA ...
Rui Luo +9 more
wiley +2 more sources
Antiviral neutralizing antibodies: from in vitro to in vivo activity
Nature reviews. Immunology, 2023 Neutralizing antibodies (nAbs) are being increasingly used as passive antiviral reagents in prophylactic and therapeutic modalities and to guide viral vaccine design.
D. Burton
semanticscholar +1 more source
BX795, a kinase inhibitor, inhibit duck plague virus infection via targeting US3 kinase
Poultry Science, 2023 : Duck plague virus (DPV) is a typical DNA virus of waterfowl, it causes huge economic losses to the duck industry due to the higher mortality and lower egg production.
Yanming Tian +18 more
doaj +1 more source
Comparative analysis of the lambda-interferons IL-28A and IL-29 regarding their transcriptome and their antiviral properties against hepatitis C virus. [PDF]
, 2010 Specific differences in signaling and antiviral properties between the different Lambda-interferons, a novel group of interferons composed of IL-28A, IL-28B and IL-29, are currently unknown.
Ralf Bartenschlager +19 more
core +1 more source