Results 51 to 60 of about 438,323 (304)

Antiviral Activity of Interferon Alpha-2b and Taurine Combination Against SARS-CoV-2 in vitro

Антибиотики и Химиотерапия, 2022
Interferons (IFN) have antiviral activity against many viruses, including SARS-CoV-2. A combination of IFN-a2b and the antioxidant taurine is widely used in the Russian Federation, and its antiviral activity has not been studied before.
N. P. Kartashova, A. V. Ivanina, E. A. Glubokova, I. N. Falynskova, A. A. Poromov, I. A. Leneva   +5 more
doaj   +1 more source

Crucial Role of Selenium in the Virucidal Activity of Benzisoselenazol-3(2H)-ones and Related Diselenides

Molecules, 2010
Various N-substituted benzisoselenazol-3(2H)-ones and their non-selenium-containing analogues have been synthesized and tested against selected viruses (HHV-1, EMCV and VSV) to determine the extent to which selenium plays a role in antiviral activity ...
Jacek Mlochowski, Magdalena Pietka-Ottlik, Piotr Potaczek, Egbert Piasecki   +3 more
doaj   +1 more source

Viruses and the cellular RNA decay machinery. [PDF]

, 2010
The ability to control cellular and viral gene expression, either globally or selectively, is central to a successful viral infection, and it is also crucial for the host to respond and eradicate pathogens.
Gaglia, Marta, Glaunsinger, Britt
core   +1 more source

Chlorhexidine-filled porous ceramic coating fabricated by the aerosol deposition method for immediate and long-term enveloped virus inactivation

Journal of Asian Ceramic Societies, 2022
We developed an antiviral ceramic coating for immediate and long-term enveloped virus inactivation. The coating consisted of a porous ceramic coating fabricated by aerosol deposition and filled with chlorhexidine (CHX).
Taku Goto, Yoichi Yamada, Takeji Ueda, Sumiko Shiota, Mitsugu Sohma, Jun Akedo   +5 more
doaj   +1 more source

Late phase inhibition of murine cytomegalovirus replication by synergistic action of interferon-gamma and tumour necrosis factor [PDF]

, 1994
We have shown previously that the antiviral function of CD4+ T lymphocytes against murine cytomegalovirus (MCMV) is associated with the release of interferon- (IFN-).
Hengel, Hartmut, Jonjic, Stipan, Koszinowski, Ulrich H., Lucin, Pero, Messerle, Martin, Polic, Bojan   +5 more
core   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Antiviral Effects and Mechanisms of Active Ingredients in Tea

Molecules
Viruses play a significant role in human health, as they can cause a wide range of diseases, from mild illnesses to severe and life-threatening conditions.
Xinghai Zhang, Haonan Yu, Panjie Sun, Mengxin Huang, Bo Li   +4 more
doaj   +1 more source

Viral-inducible Argonaute18 confers broad-spectrum virus resistance in rice by sequestering a host microRNA

eLife, 2015
Viral pathogens are a major threat to rice production worldwide. Although RNA interference (RNAi) is known to mediate antiviral immunity in plant and animal models, the mechanism of antiviral RNAi in rice and other economically important crops is poorly ...
Jianguo Wu, Zhirui Yang, Yu Wang, Lijia Zheng, Ruiqiang Ye, Yinghua Ji, Shanshan Zhao, Shaoyi Ji, Ruofei Liu, Le Xu, Hong Zheng, Yijun Zhou, Xin Zhang, Xiaofeng Cao, Lianhui Xie, Zujian Wu, Yijun Qi, Yi Li   +17 more
doaj   +1 more source

Antiviral Activities of Amniotic Fluid

Experimental Biology and Medicine, 1981
AbstractBecause viral infection in pregnancy can be a threat to the developing fetus, the identification and quantification of any protective factors operating on behalf of the offspring may be important. We have, therefore, assayed human amniotic fluid for factors influencing viral growth and have found that such fluid does not contain substances with
T, Cesario, A, Goldstein, M, Lindsey, K, Dumars, J, Tilles   +4 more
openaire   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source