Avaliação da citotoxicidade, da genotoxicidade e da potencial atividade antiviral da violaceína, produzida pela Chromobacterium violaceum [PDF]
, 2003 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em Farmácia.Os produtos naturais constituem uma fonte inesgotável de compostos com atividades farmacológicas promissoras, incluindo ...
Fröhner, Carla Regina Andrighetti
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Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Optimization of the antiviral spectrum of cyclophilin inhibitors targeting respiratory viruses
Antimicrobial Agents and ChemotherapyWe evaluated the antiviral activity of a library of 36 urea-based small-molecule cyclophilin inhibitors (SMCypIs) against human respiratory syncytial virus (hRSV) and human metapneumovirus (hMPV).
Laurent Softic +11 more
doaj +1 more source
Antiviral activity of DDD85646 against various picornaviruses.
, 2018 Antiviral activity of DDD85646 against various picornaviruses.
Julia Stanger (5598371) +10 more
core +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Bulletin of Pharmaceutical Sciences. Assiut UniversityFoot-and-mouth disease virus (FMDV) is a highly contagious virus which is affecting livestock globally. Natural products, such as essential oils, are known for their antimicrobial activity and may offer antiviral effects. This study aimed to evaluate the
Maha Khashbah +4 more
doaj +1 more source
SERINC Proteins Potentiate Antiviral Type I IFN Induction and Proinflammatory Signaling Pathways
Proceedings, 2020 T cell SERINC proteins were recently identified as human immunodeficiency virus (HIV) restriction factors that diminish viral infectivity by incorporation into virions.
Cong Zeng +8 more
doaj +1 more source
Antiviral activity against HSV-2 acyclovir resistant.
, 2017 Antiviral activity against HSV-2 acyclovir resistant.
Cinzia Sanna (612766) +9 more
core +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Honey as an antiviral agent against respiratory syncytial virus [PDF]
, 2011 Respiratory syncytial virus is the most frequent cause of hospitalization for viral respiratory infections in infants and young children worldwide. It also severely affects immunocompromised adults and the elderly, however, despite decades of efforts ...
Zareie, Parvaneh Palma
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