Results 21 to 30 of about 438,323 (304)

Multiple effects of silymarin on the hepatitis C virus lifecycle [PDF]

, 2010
Silymarin, an extract from milk thistle (Silybum marianum), and its purified flavonolignans have been recently shown to inhibit hepatitis C virus (HCV) infection, both in vitro and in vivo.
Bourne, Nigel, Brimacombe, Claire L, Cao, Feng, Graf, Tyler N, Grove, Joe, Kane, Olivia J, Lohmann, Volker, Martinez, Laura E, McKeating, Jane A, Nahmias, Yaakov, Negash, Amina, Oberlies, Nicholas H, Owen, David M, Polyak, Stephen J, Pécheur, Eve-Isabelle, Tavis, John E, Wagoner, Jessica   +16 more
core   +1 more source

BX795, a kinase inhibitor, inhibit duck plague virus infection via targeting US3 kinase

Poultry Science, 2023
: Duck plague virus (DPV) is a typical DNA virus of waterfowl, it causes huge economic losses to the duck industry due to the higher mortality and lower egg production.
Yanming Tian, Bin Tian, Mingshu Wang, Dongjie Cai, Anchun Cheng, Wei Zhang, Ying Wu, Qiao Yang, Xuming Ou, Di Sun, Shaqiu Zhang, Sai Mao, XinXin Zhao, Juan Huang, Qun Gao, Dekang Zhu, Renyong Jia, Shun Chen, Mafeng Liu   +18 more
doaj   +1 more source

A human genome-wide loss-of-function screen identifies effective chikungunya antiviral drugs [PDF]

, 2016
Chikungunya virus (CHIKV) is a globally spreading alphavirus against which there is no commercially available vaccine or therapy. Here we use a genome-wide siRNA screen to identify 156 proviral and 41 antiviral host factors affecting CHIKV replication ...
Berre, Stefano, Bracher, Franz, Braun, Peter, Couderc, Thérèsr, Gangneux, Nicolas, Karlas, Alexander, Karo-Astover, Liis, Klemm, Uwe, Lecuit, Marc, Merits, Andres, Meyer, Michael, Meyer, Thomas F., Raftery, Martin, Schönrich, Günther, Varjak, Margus, Weege, Friderike, Wurzlbauer, Anne   +16 more
core   +5 more sources

Class A scavenger receptor 1 (MSR1) restricts hepatitis C virus replication by mediating toll-like receptor 3 recognition of viral RNAs produced in neighboring cells [PDF]

, 2013
Persistent infections with hepatitis C virus (HCV) may result in life-threatening liver disease, including cirrhosis and cancer, and impose an important burden on human health.
Dansako, Hiromichi, Hu, Fengyu, Kato, Nobuyuki, Lemon, Stanley M., McGivern, David R., Welsch, Christoph, Yamane, Daisuke   +6 more
core   +12 more sources

In vitro synergy and enhanced murine brain penetration of saquinavir coadministered with mefloquine. [PDF]

, 2005
Highly active antiretroviral therapy has substantially improved prognosis in human immunodeficiency virus (HIV). However, the integration of proviral DNA, development of viral resistance, and lack of permeability of drugs into sanctuary sites (e.g ...
Back, DJ, Bray, PG, Chandler, B, Hart, CA, Hartkoorn, RC, Janneh, O, Khoo, SH, Martin, P, Owen, A, Ward, SA   +9 more
core   +1 more source

Antiviral and virucidal activity of sodium deoxyribonucleate and its complex with iron against viruses of different kingdoms and families

Вопросы вирусологии, 2023
Introduction. The urgent problem of modern medicine is the fight against acute respiratory viral infections (ARVI). To combat ARVI, drugs of wide antiviral potency are needed, as well as immunomodulating drugs. Such antiviral and immunomodulatory effects
Dmitry N. Nosik, Lyudmila B. Kalnina, Olga A. Lobach, Marina S. Chataeva, Elena V. Berezhnaya, Marina S. Bochkova, Irina A. Kiseleva, Lyudmila M. Selimova, Nikolai N. Nosik   +8 more
doaj   +1 more source

The antiviral RNAi response in vector and non-vector cells against orthobunya viruses [PDF]

, 2017
Background: Vector arthropods control arbovirus replication and spread through antiviral innate immune responses including RNA interference (RNAi) pathways. Arbovirus infections have been shown to induce the exogenous small interfering RNA (siRNA) and
Bausch, DG, Blomström, AL, Dietrich, I, Elliott, RM, Kohl, A, McFarlane, M, Schnettler, E, Shi, X, Skelton, JK, Watson, M   +9 more
core   +5 more sources

Functional foods with antiviral activity

Food Science and Biotechnology, 2022
Viruses are known to cause a variety of diseases, ranging from mild respiratory diseases, such as the common cold, to fatal illnesses. Although the development of vaccines and targeted drugs have significantly improved the mortality rate and disease severity against a number of viral infections, there are still many viruses without proper treatment ...
Kim, Da Hyun, Kim, Jae Hwan, Kim, Da Hyun, Jo, Jay-Young, Byun, Sanguine   +4 more
openaire   +2 more sources

Antiviral Activity of Extracts

Natural Product Communications, 2012
The antiviral activity was tested of different polarity extracts, with differing chemical composition, obtained from aerial parts of Heterophyllaea pustulata Hook f.
Brenda S. Konigheim, Mauricio Beranek, Laura R. Comini, Javier J. Aguilar, Juliana Marioni, José L. Cabrera, Marta S. Contigiani, Susana C. Núñez Montoya   +7 more
doaj   +1 more source

Cyclopentenylcytosine (CPE-C): In Vitro and In Vivo Evaluation as an Antiviral against Adenoviral Ocular Infections

Molecules, 2023
Adenoviruses are the major cause of ocular viral infections worldwide. Currently, there is no approved antiviral treatment for these eye infections. Cyclopentenylcytosine (CPE-C) is an antiviral that has demonstrated activity against more than 20 viruses.
Eric G. Romanowski, Kathleen A. Yates, Y. Jerold Gordon   +2 more
doaj   +1 more source