Results 11 to 20 of about 5,266 (113)

Exploring the Antiviral Potential of Tungsten Oxide Nanoparticles Against Herpes Simplex Virus Type 1: A Promising Alternative to Acyclovir. [PDF]

IET Nanobiotechnol
Herpes simplex virus type 1 (HSV‐1) is responsible for the majority of cold sores, herpetic keratitis‐induced blindness, profound skin lesions, and encephalitis that can be fatal. Currently, acyclovir and its derivatives are the first‐line therapy for the treatment of HSV‐1 infection.
Jwaziri AK, Khales P, Kiani SJ, Yaghouti H, Babaei R, Salavatiha Z, Tavakoli A.   +6 more
europepmc   +2 more sources

Characteristics of the pulmonary microbiota in patients with mild and severe pulmonary infection. [PDF]

Front Cell Infect Microbiol, 2023
BackgroundLung infection is a global health problem associated with high morbidity and mortality and increasing rates of hospitalization. The correlation between pulmonary microecology and infection severity remains unclear.
Zhan D, Li D, Yuan K, Sun Y, He L, Zhong J, Wang L.   +6 more
europepmc   +2 more sources

Antiviral activity of the organic germanium complex with aciclovir against herpes simplex virus (Herpesviridae: Alphaherpesvirinae: Simplexvirus: Human alphaherpesvirus 1/2) in the in vitro and in vivo systems

Problems of Virology, 2021
Introduction. A significant increase in the incidence of various forms of herpesvirus infection (HVI) determines the need to search for new approaches to the modification of one of the basic antiviral drugs aciclovir (ACV) and its dosage forms to improve their biopharmaceutical characteristics and increase the effectiveness of therapy.
L. M. Alimbarova, I. V. Ambrosov, S. K. Matelo, I. F. Barinsky   +3 more
openaire   +5 more sources

CRISPR-Cas genome editing system in the diagnosis and therapy of infection caused by herpes simplex virus type 1 (<i>Orthoherpesviridae: Alphaherpesviridae: Simplexvirus: Simplexvirus humanalpha1</i>)

Problems of Virology
Herpes simplex virus type 1 (HSV-1), newly named as Simplexvirus humanalpha1 is one of the most common pathogens in the human population, which can cause severe disease, often with fatal outcomes. Diagnostic methods currently in use are specific and sensitive, but time-consuming, require expensive laboratory equipment and highly qualified personnel ...
Natalia A. Demidova, Regina R. Klimova, Alla A. Kushch, Dmitry S. Karpov   +3 more
openaire   +4 more sources

A review of latency in the Alloherpesviridae family. [PDF]

J Fish Dis
Abstract The ability to impact the immune response of the host has been recognized as essential for the success of a virus during infection. A few groups of viruses can combine these immunomodulatory mechanisms with specific patterns of their own transcriptional and replication regulation to achieve persistence within the host long term.
Quijano Cardé EM, Soto E.
europepmc   +2 more sources

Generation, characterization, and application of caprine herpesvirus 1 secreted glycoprotein D. [PDF]

Microbiol Spectr
Caprine herpesvirus 1 (CpHV-1), a member of the Herpesvirales order, Herpesviridae family, Alphaherpesvirinae subfamily, and Simplexvirus genus, is classically associated with two distinct clinical syndromes.
Minesso S, Odigie AE, Franceschi V, Taddei S, Madia V, Tempesta M, Donofrio G.   +6 more
europepmc   +2 more sources

Antiviral activity of extracts of basidiomycetes and humic compounds substances against Human Immunodeficiency Virus (Retroviridae: Orthoretrovirinae: Lentivirus: Human immunodeficiency virus 1) and Herpes Simplex Virus (Herpesviridae: Simplexvirus: Human alphaherpesvirus 1)

Problems of Virology, 2020
Introduction. One of the most urgent problem of modern medicine is the fight against the disease caused by the Human Immunodeficiency Virus (HIV) – HIV infection. The chemical compounds have improved the situation for infected people, but they are toxic, disrupt the metabolism and cannot eliminate the integrated virus from the body.
D. N. Nosik, N. N. Nosik, T. V. Teplyakova, O. A. Lobach, I. A. Kiseleva, N. G. Kondrashina, M. S. Bochkova, G. G. Ananko   +7 more
openaire   +5 more sources

Equine histones are mobilized within equid alphaherpesvirus 1 (EHV1) replication compartments. [PDF]

J Virol
Equid alphaherpesvirus 1 (EHV1) is a DNA virus that causes severe disease in equids. Some strains are neurotropic and cause disease in the central nervous system, whereas others are non-neurotropic and can cause negative reproductive outcomes. Mechanisms
Conn KL.
europepmc   +2 more sources

Seroprevalence of herpes simplex virus type 1 (Herpesviridae: <i>Simplexvirus: Human alphaherpesvirus 1</i>) in smokers

Problems of Virology
Introduction. Herpes simplex virus type 1 (HSV-1) is one of the most common human viral infections and has a double-stranded DNA genome belonging to the Herpesviridae family. Smoking is one of the leading causes of disease and premature death worldwide, responsible for the death of up to six million people annually. The purpose of the current study was
Jalil B. Mays, Mohammed Ali N. Mariem, Hadi I. Alabadi   +2 more
openaire   +3 more sources

A broad wastewater screening and clinical data surveillance for virus-related diseases in the metropolitan Detroit area in Michigan. [PDF]

Hum Genomics
Background Periodic bioinformatics-based screening of wastewater for assessing the diversity of potential human viral pathogens circulating in a given community may help to identify novel or potentially emerging infectious diseases.
Li Y, Miyani B, Faust RA, David RE, Xagoraraki I.   +4 more
europepmc   +2 more sources