Tissue Nonspecific Alkaline Phosphatase (TNAP) Regulates Cranial Base Growth and Synchondrosis Maturation [PDF]
, 2017 Hwa K. Nam +3 more
core +1 more source
PCR detection of a Bc/l RFLP in the human ALPL gene
Nucleic Acids Research, 1991 T, Okuyama +3 more
openaire +3 more sources
Loss-of-Function Mutations in the ALPL Gene Presenting with Adult Onset Osteoporosis and Low Serum Concentrations of Total Alkaline Phosphatase. [PDF]
J Bone Miner Res, 2020 Alonso N +9 more
europepmc +1 more source
Notch signaling suppresses glucose metabolism in mesenchymal progenitors to restrict osteoblast differentiation [PDF]
, 2018 Fanxin Long +5 more
core +2 more sources
Regulation of osteoblast development by Bcl-2-associated athanogene-1 (BAG-1)
BCL-2-associated athanogene-1 (BAG-1) is expressed by osteoblast-lineage cells; early embryonic lethality in Bag-1 null mice, however, has limited the investigation of BAG-1 function in osteoblast development.
Cutress, Ramsey +5 more
core +1 more source
Hypophosphatasia: 90 Years from a Canadian Discovery-A Comprehensive Review of the <i>ALPL</i> Gene Underlying Rathbun's Syndrome. [PDF]
Genes (Basel)Sergi CM.
europepmc +1 more source
Epidemiological, Clinical and Genetic Study of Hypophosphatasia in A Spanish Population: Identification of Two Novel Mutations in The Alpl Gene. [PDF]
Sci Rep, 2019 García-Fontana C +9 more
europepmc +1 more source
Hypophosphatasia and the risk of atypical femur fractures: a case–control study [PDF]
, 2016 core +1 more source
The effect of exposure to nanoparticles and nanomaterials on the mammalian epigenome [PDF]
, 2016 Fernández Fernández, Agustín +4 more
core +1 more source
Novel mutation in the ALPL gene with a dominant negative effect in a Japanese family
Novel mutation in the ALPL gene with a dominant negative effect in a Japanese familyIntroduction Hypophosphatasia (HPP) is caused by mutations in the ALPL gene encoding tissue nonspecific alkaline phosphatase (TNSALP) and inherited in either an autosomal recessive or autosomal dominant manner. It is characterized clinically by defective mineralization of bone, dental problems, and low serum ALP levels.
openaire