Results 91 to 100 of about 12,421 (264)

The role of cyclooxygenase-2 (COX-2) and inflammatory markers in the progress of Alport syndrome in Egyptian children

BMC Pediatrics
Background Chronic inflammation and its control are crucial to the responses of glomerular and renal tubular cells. This contributes to the pathogenic mechanisms and advancement of the disease in Alport syndrome.
Moushira Zaki, Hisham A. Orban, Mohamed A. Shahba, Rehab S. I. Moustafa, Ahmed Adel, Fatina I. Fadel, Abeer Selim, Hala T. El-Bassyouni, Eman R. Youness   +8 more
doaj   +1 more source

Complete Atrioventricular Block in a Young Patient With Alport Syndrome: A Case Report

Annals of Internal Medicine: Clinical Cases
Complete atrioventricular block (AVB) has not been previously reported in patients with Alport syndrome with normal kidney function. We describe a rare case of a young man with Alport syndrome who developed complete AVB.
Zuoyi Zhou, Long Zhang, Qinhui Sheng, Yanjun Gong, Jianping Li   +4 more
doaj   +1 more source

Multimorbidity:will it stand the test of time? [PDF]

, 2017
The concept of multimorbidity has risen in popularity over the past few years. It is use has led to, or coincided with, an increased recognition that patients often have more than one health problem which should not be treated in isolation.
Ford, Joanna C, Ford, John A
core   +1 more source

The alliance between genetic biobanks and patient organisations: the experience of the telethon network of genetic biobanks [PDF]

, 2016
Background: Rare diseases (RDs) are often neglected because they affect a small percentage of the population (6-8 %), which makes research and development of new therapies challenging processes. Easy access to high-quality samples and associated clinical
Alessandra Renieri, Barbara Garavaglia, Chiara Baldo, Chiara Barzaghi, Chiuhui Mary Wang, Elena Pegoraro, Giuseppe Merla, Ilaria Meloni, Lorena Casareto, Luca Sangiorgi, Lucia Monaco, Luisa Politano, Maria Teresa Pellico, Marina Mora, Maurizio Moggio, Mirella Filocamo, Raffaella Mazzotti, Stefano Goldwurm, Valeria Viotti   +18 more
core   +4 more sources

Genome-wide signatures of complex introgression and adaptive evolution in the big cats. [PDF]

, 2017
The great cats of the genus Panthera comprise a recent radiation whose evolutionary history is poorly understood. Their rapid diversification poses challenges to resolving their phylogeny while offering opportunities to investigate the historical ...
Antunes, Agostinho, Assis, Juliana, Azevedo, Fernando CC, Bi, Ke, Brassaloti, Ricardo A, Coutinho, Luiz L, Eizirik, Eduardo, Fernandes, Gabriel, Figueiró, Henrique V, Gabaldón, Toni, Hughes, Graham M, Kantek, Daniel, Komissarov, Aleksey, Li, Gang, Linderoth, Tyler, Loska, Damian, Morato, Ronaldo G, Murphy, William J, Nielsen, Rasmus, Nunes, Adauto LV, O'Brien, Stephen J, Oliveira, Guilherme, Pais, Fabiano, Ramalho, Emiliano, Rodrigues, Maíra R, Santos, Sarah HD, Saragüeta, Patricia, Silveira, Leandro, Teeling, Emma C, Teixeira, Rodrigo HF, Trinca, Cristine S, Trindade, Fernanda J, Villela, Priscilla MS   +32 more
core   +5 more sources

Increased in vivo transduction of AAV-9 cargo in Alport podocytes [version 1; peer review: 1 approved, 2 approved with reservations, 1 not approved]

Wellcome Open Research
Background Alport syndrome is a rare genetic disorder characterized by progressive kidney disease, hearing loss, and eye abnormalities. It is caused by variants in the COL4A3, COL4A4 or COL4A5 genes, which disrupt the synthesis, secretion and assembly of
Emily Williams, Kevin A. Goncalves, Shota Kaseda, Antony Adamson, Maryline Fresquet, Andrew Steinsapir, David R. Sherwood, Rachel Lennon, Gema Bolas   +8 more
doaj   +1 more source

Alport syndrome: our knowledge update

, 2021
Marina Aksenova
openalex   +1 more source

Alport Syndrome and Femtosecond Laser-assisted Cataract Surgery

Journal of Ophthalmic & Vision Research, 2020
We report the surgical management of a patient with bilateral anterior lenticonus due to Alport syndrome using femtosecond laser-assisted cataract surgery (FLACS) and the Optiwave Refractive Analysis (ORA) system.
Paz Orts-Vila, Francisco Amparo, José Luís Rodríguez-Prats, Pedro Tañá-Rivero   +3 more
doaj   +1 more source

Renal function and physical fitness after 12-mo supervised training in kidney transplant recipients [PDF]

, 2018
To evaluate the effect of a 12-mo supervised aerobic and resistance training, on renal function and exercise capacity compared to usual care ...
Andreoli, Lucia, Anedda, Alberto, Angelini, Maria Laura, Brugin, Erica, Di Michele, Rocco, Ermolao, Andrea, Galanti, Giorgio, La Manna, Gaetano, Merlo, Laura, Merni, Franco, Mosconi, Giovanni, Nanni Costa, Alessandro, Roi, GIULIO SERGIO, Sarto, Patrizio, Sella, Gianluigi, Sgarzi, Sergio, Stancari, Michele, Stefani, Laura, Storani, Daniela, Todeschini, Paola, Totti, Valentina, Trerotola, Manuela, Tripi, Ferdinando   +22 more
core   +1 more source

Author response: Empagliflozin reduces podocyte lipotoxicity in experimental Alport syndrome

, 2023
Mengyuan Ge, Judith Molina, Jin‐Ju Kim, Shamroop Kumar Mallela, Anis Ahmad, Javier Varona Santos, Hassan Al‐Ali, Alla Mitrofanova, Kumar Sharma, Flavia Fontanesi, Sandra Merscher, Alessia Fornoni   +11 more
openalex   +1 more source