Journal of Traditional and Complementary Medicine, 2014 Ischemia–reperfusion (I/R) injury has a complex pathophysiology resulting from a number of contributing factors. Therefore, it is difficult to achieve effective treatment or protection by individually targeting the mediators or mechanisms. Our aim was to
Cheng-Chu Hsieh +3 more
doaj +2 more sources
Alprostadil attenuates myocardial ischemia/reperfusion injury by promoting antioxidant activity and eNOS activation in rats [PDF]
Acta Cirúrgica Brasileira, 2018 Purpose: To investigate the effect of alprostadil on myocardial ischemia/reperfusion (I/R) in rats. Methods: Rats were subjected to myocardial ischemia for 30 min followed by 24h reperfusion.
Liping Zhang +5 more
doaj +2 more sources
Efficacy of alprostadil for preventing of contrast-induced nephropathy: A meta-analysis [PDF]
Scientific Reports, 2017 Contrast-induced nephropathy (CIN) has become the third-leading cause of hospital-acquired acute renal injury. Although alprostadil has been proposed as an effective preventative measure, this conclusion remains inconsistent.
Jing-Zhan Zhang +10 more
doaj +2 more sources
Peripheral Female Genital Arousal as Assessed by Thermography Following Topical Genital Application of Alprostadil vs Placebo Arousal Gel: A Proof-of-Principle Study Without Visual Sexual Stimulation [PDF]
Sexual Medicine, 2016 Introduction: Female sexual arousal disorder is a pathophysiologic state characterized clinically by persistent or recurrent inability to attain or maintain an adequate lubrication-swelling response of sexual excitement until completion of sexual ...
Sue W. Goldstein, BA, CCRC, IF +3 more
doaj +2 more sources
Alprostadil attenuates inflammatory aspects and leucocytes adhesion on renal ischemia and reperfusion injury in rats [PDF]
Acta Cirúrgica Brasileira, 2014 PURPOSE: To evaluate the effects of alprostadil in an experimental model of ischemia and reperfusion injury (IRI) in rat renal tissue.METHODS:Adult male Wistar rats were randomized into three groups Vehicle-treated group(Veh), Alprostadil-treated(Al ...
Bruno Leonardo de Freitas Soares +4 more
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Alprostadil cream in the treatment of erectile dysfunction: clinical evidence and experience [PDF]
Therapeutic Advances in Urology, 2016 Erectile dysfunction (ED) is a very common disorder with a deep impact on quality of life on both patients and partners. Several options are available for treating ED: oral pharmacotherapy with phosphodiesterase 5 (PDE5) inhibitors currently represents ...
Béatrice Cuzin
doaj +2 more sources
Physical compatibility of insulin aspart, lidocaine, alprostadil and vancomycin with individualised two-in-one parenteral nutrition used in the neonatal intensive care unit. [PDF]
Eur J Hosp PharmVan Gelder TG +7 more
europepmc +3 more sources
Combination drug therapy prevents CIAKI by suppressing ER stress-induced apoptosis [PDF]
Scientific ReportsContrast-induced acute kidney injury (CIAKI) is an important clinical complication that occurs after the application of contrast agent in percutaneous coronary intervention. The pathogenesis of CIAKI is complex.
Xuan Wang +3 more
doaj +2 more sources
Journal of Research in Medical Sciences, 2013 Background: After reestablishment of blood flow to ischemic limb recirculation of free radicals may cause ischemia-reperfusion injury in many organs. This study designed to investigate effects of hydrocortisone and alprostadil distant injury to kidneys ...
Ali Ebrahimi +7 more
doaj +2 more sources