Results 11 to 20 of about 2,723 (157)
Journal of Pharmacological Sciences, 2013 Alprostadil (lipo-PGE1) is a drug delivery system preparation. This preparation is applied to treat refractory skin ulcers and arteriosclerosis obliterans. We investigated the effects of alprostadil by using the earflap ischemic model.
Masaki Aihara
exaly +3 more sources
Journal of Traditional and Complementary Medicine, 2014 Ischemia–reperfusion (I/R) injury has a complex pathophysiology resulting from a number of contributing factors. Therefore, it is difficult to achieve effective treatment or protection by individually targeting the mediators or mechanisms. Our aim was to
Shu-Chen Hsieh +2 more
exaly +3 more sources
Alprostadil cream in the treatment of erectile dysfunction: clinical evidence and experience
Therapeutic Advances in Urology, 2016 Erectile dysfunction (ED) is a very common disorder with a deep impact on quality of life on both patients and partners. Several options are available for treating ED: oral pharmacotherapy with phosphodiesterase 5 (PDE5) inhibitors currently represents ...
Béatrice Cuzin
exaly +2 more sources
Open Medicine (Poland), 2017 To evaluate the effect and toxicity of alprostadil combined with thioctic acid injection in the treatment of patients with diabetic nephropathy (DN).
Hong Yan +5 more
exaly +2 more sources
Combination drug therapy prevents CIAKI by suppressing ER stress-induced apoptosis [PDF]
Scientific ReportsContrast-induced acute kidney injury (CIAKI) is an important clinical complication that occurs after the application of contrast agent in percutaneous coronary intervention. The pathogenesis of CIAKI is complex.
Xuan Wang +3 more
doaj +2 more sources
High-Throughput Heterospheroid-Based Screening Identifies Drugs That Reprogram Tumor-Associated Macrophages. [PDF]
J Immunol ResThe tumor microenvironment (TME) provides a niche for immune evasion and immunotherapy resistance, in part, by recruiting pro‐tumor M2‐like macrophages. In the present study, using heterospheroids consisting of cancer cells and macrophages, we identified TAM activators, which are compounds that reprogram M2‐like tumor‐associated macrophages (TAMs ...
Tsuchiya H +6 more
europepmc +2 more sources
Revista Portuguesa de Cardiologia, 2022 Objectives: Our study aimed to investigate the effects of alprostadil and Salvia miltiorrhiza extract on myocardial ischemia-reperfusion injury (IRI) and related underlying molecular mechanisms.
Jing Liu +8 more
doaj +1 more source
Risk of priapism after dynamic penile Doppler ultrasound: Single-centre experience on a large cohort of patients. [PDF]
AndrologyAbstract Objectives To evaluate the risk of priapism in patients undergoing Dynamic—Penile duplex ultrasound (D‐PDU) who were referred to our Unit between January 2022 and December 2023. Patients and methods We enrolled 292 patients, of whom 268 underwent Dynamic—Penile duplex ultrasound for erectile dysfunction and 24 for Peyronie's disease.
Grande G +6 more
europepmc +2 more sources
Frontiers in Cardiovascular Medicine, 2022 BackgroundThe optimum therapy for coronary slow flow phenomenon (CSFP) stays debatable. This study compared the effectiveness of alprostadil with isosorbide dinitrate in alleviating angina episodes in CSFP patients.MethodsIn this prospective, randomized ...
Weifeng Zhang +15 more
doaj +1 more source