Results 1 to 10 of about 2,641 (140)
Journal of Pharmacological Sciences, 2013 Alprostadil (lipo-PGE1) is a drug delivery system preparation. This preparation is applied to treat refractory skin ulcers and arteriosclerosis obliterans. We investigated the effects of alprostadil by using the earflap ischemic model.
Masaki Aihara
exaly +3 more sources
Journal of Traditional and Complementary Medicine, 2014 Ischemia–reperfusion (I/R) injury has a complex pathophysiology resulting from a number of contributing factors. Therefore, it is difficult to achieve effective treatment or protection by individually targeting the mediators or mechanisms. Our aim was to
Shu-Chen Hsieh, Jen-Hwey Chiu
exaly +3 more sources
Alprostadil cream in the treatment of erectile dysfunction: clinical evidence and experience
Therapeutic Advances in Urology, 2016 Erectile dysfunction (ED) is a very common disorder with a deep impact on quality of life on both patients and partners. Several options are available for treating ED: oral pharmacotherapy with phosphodiesterase 5 (PDE5) inhibitors currently represents ...
Béatrice Cuzin
exaly +2 more sources
Combination drug therapy prevents CIAKI by suppressing ER stress-induced apoptosis [PDF]
Scientific ReportsContrast-induced acute kidney injury (CIAKI) is an important clinical complication that occurs after the application of contrast agent in percutaneous coronary intervention. The pathogenesis of CIAKI is complex.
Xuan Wang +3 more
doaj +2 more sources
Revista Portuguesa de Cardiologia, 2022 Objectives: Our study aimed to investigate the effects of alprostadil and Salvia miltiorrhiza extract on myocardial ischemia-reperfusion injury (IRI) and related underlying molecular mechanisms.
Jing Liu +8 more
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2022 BackgroundThe optimum therapy for coronary slow flow phenomenon (CSFP) stays debatable. This study compared the effectiveness of alprostadil with isosorbide dinitrate in alleviating angina episodes in CSFP patients.MethodsIn this prospective, randomized ...
Weifeng Zhang +15 more
doaj +1 more source
Alprostadil attenuates myocardial ischemia/reperfusion injury by promoting antioxidant activity and eNOS activation in rats [PDF]
Acta Cirúrgica Brasileira, 2018 Purpose: To investigate the effect of alprostadil on myocardial ischemia/reperfusion (I/R) in rats. Methods: Rats were subjected to myocardial ischemia for 30 min followed by 24h reperfusion.
Liping Zhang +5 more
doaj +1 more source
Modern aspects of diagnosis and treatment of obliterating atherosclerosis of the lower extremities
Лечащий Врач, 2023 Currently, diseases of the arteries of the lower extremities are an urgent problem of modern medicine, one of the most common variants of peripheral artery diseases.
V. V. Skvortsov +2 more
doaj +1 more source
Journal of Interventional Cardiology, 2023 Background. In-stent restenosis (ISR) is a common complication after percutaneous coronary intervention (PCI) surgery for patients with coronary atherosclerotic heart disease (CHD).
Decai Zhu +5 more
doaj +1 more source