Journal of Traditional and Complementary Medicine, 2014 Ischemia–reperfusion (I/R) injury has a complex pathophysiology resulting from a number of contributing factors. Therefore, it is difficult to achieve effective treatment or protection by individually targeting the mediators or mechanisms. Our aim was to
Shu-Chen Hsieh, Jen-Hwey Chiu
exaly +4 more sources
Alprostadil attenuates inflammatory aspects and leucocytes adhesion on renal ischemia and reperfusion injury in rats [PDF]
Acta Cirúrgica Brasileira, 2014 PURPOSE: To evaluate the effects of alprostadil in an experimental model of ischemia and reperfusion injury (IRI) in rat renal tissue.METHODS:Adult male Wistar rats were randomized into three groups Vehicle-treated group(Veh), Alprostadil-treated(Al ...
Bruno Leonardo de Freitas Soares +4 more
doaj +6 more sources
Alprostadil attenuates myocardial ischemia/reperfusion injury by promoting antioxidant activity and eNOS activation in rats [PDF]
Acta Cirúrgica Brasileira, 2018 Purpose: To investigate the effect of alprostadil on myocardial ischemia/reperfusion (I/R) in rats. Methods: Rats were subjected to myocardial ischemia for 30 min followed by 24h reperfusion.
Liping Zhang +5 more
doaj +2 more sources
Efficacy of alprostadil for preventing of contrast-induced nephropathy: A meta-analysis [PDF]
Scientific Reports, 2017 Contrast-induced nephropathy (CIN) has become the third-leading cause of hospital-acquired acute renal injury. Although alprostadil has been proposed as an effective preventative measure, this conclusion remains inconsistent.
Jing-Zhan Zhang +10 more
doaj +2 more sources
Journal of Pharmacological Sciences, 2013 Alprostadil (lipo-PGE1) is a drug delivery system preparation. This preparation is applied to treat refractory skin ulcers and arteriosclerosis obliterans. We investigated the effects of alprostadil by using the earflap ischemic model.
Hajime Inoue +3 more
exaly +3 more sources
Peripheral Female Genital Arousal as Assessed by Thermography Following Topical Genital Application of Alprostadil vs Placebo Arousal Gel: A Proof-of-Principle Study Without Visual Sexual Stimulation [PDF]
Sexual Medicine, 2016 Introduction: Female sexual arousal disorder is a pathophysiologic state characterized clinically by persistent or recurrent inability to attain or maintain an adequate lubrication-swelling response of sexual excitement until completion of sexual ...
Sue W. Goldstein, BA, CCRC, IF +3 more
doaj +2 more sources
The current treatment of erectile dysfunction [PDF]
Journal of Mind and Medical Sciences, 2016 Erectile dysfunction (ED) is the inability to achieve and maintain an erection sufficient for satisfactory sexual intercourse. It is the most frequent sexual dysfunction in elderly men and its prevalence increases with age.
Maria Isabela Sarbu +4 more
doaj +3 more sources
Alprostadil cream in the treatment of erectile dysfunction: clinical evidence and experience [PDF]
Therapeutic Advances in Urology, 2016 Erectile dysfunction (ED) is a very common disorder with a deep impact on quality of life on both patients and partners. Several options are available for treating ED: oral pharmacotherapy with phosphodiesterase 5 (PDE5) inhibitors currently represents ...
Béatrice Cuzin
doaj +2 more sources
Physical compatibility of insulin aspart, lidocaine, alprostadil and vancomycin with individualised two-in-one parenteral nutrition used in the neonatal intensive care unit. [PDF]
Eur J Hosp PharmVan Gelder TG +7 more
europepmc +3 more sources
DERMATOPROTECTIVE ACTIVITY OF A COMBINATION OF ENOXIFOL WITH REXOD IN A REDUCED FORM THE BLOOD CIRCULATION IN THE SKIN IN DIABETES MELLITUS AND HYPERCHOLESTERINEMIA [PDF]
Research Results in Pharmacology, 2017 Experiments in rats showed that the 9-diethylaminoethyl-2-(3,4-dioxyphenyl)-imidazo-[1,2-a]-benzimidazole dihydrobromide with the provisional name of enoxifol (0.94 – 15 mg/kg), rexod (recombinant human superoxide dismutase; 0.002 mg/kg) and especially ...
Valeria Seletskaya +1 more
doaj +7 more sources