Results 71 to 80 of about 6,046 (238)
The tumor microenvironment (TME) provides a niche for immune evasion and immunotherapy resistance, in part, by recruiting pro‐tumor M2‐like macrophages. In the present study, using heterospheroids consisting of cancer cells and macrophages, we identified TAM activators, which are compounds that reprogram M2‐like tumor‐associated macrophages (TAMs ...
Hiroyuki Tsuchiya +7 more
wiley +1 more source
Treatments for dry age-related macular degeneration and Stargardt disease : a systematic review [PDF]
Background Age-related macular degeneration (AMD) is the leading cause of visual loss in older people. Advanced AMD takes two forms, neovascular (wet) and atrophic (dry). Stargardt disease (STGD) is the commonest form of inherited macular dystrophy.
Colquitt, Jill +6 more
core +3 more sources
Relationship Between COVID‐19 and Retinal Artery Occlusions
The relationship between coronavirus disease 2019 (COVID‐19) infection or vaccination and retinal artery occlusions (RAOs) remains controversial. COVID‐19 infection or vaccination can sometimes cause thrombin formation. RAOs occur due to thrombin in the retinal artery.
Tetsuya Muto +4 more
wiley +1 more source
Surprises of off-label drug use - where had all the Prostin gone? [PDF]
The off-label use of drugs is common, particularly in paediatrics, where many drugs have yet to undergo the rigorous scrutiny demanded by authorities such as the Medicines Control Council (MCC) and the US Food and Drug Administration (FDA) before ...
De Decker, Rik +3 more
core
Attenuation of ischemic liver injury by prostaglandin E
Background: Prostaglandin has been reported to have protective effects against liver injury. Use of this agent in clinical settings, however, is limited because of drugrelated side effects.
Ishizaki, N +8 more
core +1 more source
Nanomedicines Against Mitochondrial Dysfunction‐Induced Metabolic Diseases
Mitochondrial dysfunction is central to metabolic diseases. Nanomedicine offers transformative approaches for restoring function via targeted delivery, responsive release, and multimodal therapy. This review outlines the pathological basis, nanocarrier design, organelle‐specific targeting, recent advances, and future clinical translation challenges ...
Ke Xu +9 more
wiley +1 more source
Inhaled PGE1 in neonates with hypoxemic respiratory failure: two pilot feasibility randomized clinical trials. [PDF]
BackgroundInhaled nitric oxide (INO), a selective pulmonary vasodilator, has revolutionized the treatment of neonatal hypoxemic respiratory failure (NHRF). However, there is lack of sustained improvement in 30 to 46% of infants.
Ambalavanan, Namasivayam +18 more
core +2 more sources
In Vivo Targeted Metabolomic Profiling of Prostanit, a Novel Anti-PAD NO-Donating Alprostadil-Based Drug [PDF]
Ksenia M. Shestakova +9 more
openalex +1 more source
Multiple inflammatory, infectious and autoimmune dermato‐venereological conditions are associated with erectile dysfunction (ED) due to underlying intricate vasculogenic, neurogenic, endocrine and psychogenic mechanisms. It is recommended that practitioners screen dermatology patients for ED and associated comorbidities, provide personalized lifestyle ...
Andrei Tanasov, George‐Sorin Tiplica
wiley +1 more source
Current pharmacological agents for the treatment of premature ejaculation [PDF]
This study was aimed to review and assess the update studies regarding medical treatment for premature ejaculation (PE). It is the most common sexual problem affecting men. It can affect men at all ages and has a serious impact on the quality of life for
Okan Baş, Onur Dede, Şahin Bağbancı
core +1 more source

