Results 1 to 10 of about 1,322 (182)

The Aqueous Stem Bark Extract of Alstonia boonei Exhibits Anticataract Activity in Sprague Dawley Rat [PDF]

Scientifica, 2023
In Africa, Alstonia boonei is used folklorically for the management of the multitude of conditions including cataract, which accounts for 50% of cases of blindness in the region.
Adwoa Frema Amanfo, Samuel Kyei, Yaw Duah Boakye, Clement Osei Akoto, Justice Kwaku Addo, Kofi Oduro Yeboah, Newman Osafo   +6 more
doaj   +5 more sources

A Study on Chemical Characterization and Biological Abilities of Alstonia boonei Extracts Obtained by Different Techniques [PDF]

Antioxidants, 2022
In the quest for novel therapeutic agents from plants, the choice of extraction solvent and technique plays a key role. In this study, the possible differences in the phytochemical profile and bioactivity (antioxidant and enzyme inhibitory activity) of ...
Adriano Mollica, Gokhan Zengin, Kouadio Ibrahime Sinan, Marcella Marletta, Stefano Pieretti, Azzurra Stefanucci, Ouattara Katinan Etienne, József Jekő, Zoltán Cziáky, Mir Babak Bahadori, Carene Picot-Allain, Mohamad Fawzi Mahomoodally   +11 more
doaj   +7 more sources

Antispasmodic Effect of Alstonia boonei De Wild. and Its Constituents: Ex Vivo and In Silico Approaches [PDF]

Molecules, 2023
Background: Alstonia boonei, belonging to the family Apocynaceae, is one of the best-known medicinal plants in Africa and Asia. Stem back preparations are traditionally used as muscle relaxants.
Opeyemi Josephine Akinmurele, Mubo Adeola Sonibare, Anthony A. Elujoba, Akingbolabo Daniel Ogunlakin, Oloruntoba Emmanuel Yeye, Gideon Ampoma Gyebi, Oluwafemi Adeleke Ojo, Abdullah R. Alanzi   +7 more
doaj   +4 more sources

A Review of the Ethnobotany and Pharmacological Importance of Alstonia boonei De Wild (Apocynaceae). [PDF]

ISRN Pharmacol, 2012
Alstonia booneiDe Wild is a herbal medicinal plant of West African origin, popularly known as God's tree or “Onyame dua”. Within West Africa, it is considered as sacred in some forest communities; consequently the plant parts are not eaten. The plant parts have been traditionally used for its antimalarial, aphrodisiac, antidiabetic, antimicrobial, and ...
Adotey JP, Adukpo GE, Opoku Boahen Y, Armah FA.   +3 more
europepmc   +6 more sources

Phytochemical analysis, in vitro and in silico effects from Alstonia boonei De Wild stem bark on selected digestive enzymes and adipogenesis in 3T3-L1 preadipocytes [PDF]

BMC Complementary Medicine and Therapies, 2023
Background Obesity is a global health issue arising from the unhealthy accumulation of fat. Medicinal plants such as Alstonia boonei stem bark has been reported to possess body weight reducing effect in obese rats.
Gabriel O. Anyanwu, Uju D. Ejike, Gideon A. Gyebi, Khalid Rauf, Nisar-Ur-Rehman, Jamshed Iqbal, Sumera Zaib, Usunomena Usunobun, Eusebius C. Onyeneke, Badriyah S. Alotaibi, Gaber El-Saber Batiha   +10 more
doaj   +2 more sources

Toxicology of solvent extract and fractions of Alstonia boonei (DC.) Wild stem bark in Rats [PDF]

Journal of HerbMed Pharmacology, 2018
Introduction: Toxic effects arising from the use of medicinal herbs have been frequently overshadowed by the therapeutic efficacy of phytomedicines. This study was carried out to assess the safety of extract and fractions of Alstonia boonei (de wild ...
Oludele John Olanlokun, Olufunso Olabode Olorunsogo   +1 more
doaj   +4 more sources

Pharmacognostic Characteristics and Mutagenic Studies of Alstonia boonei De Wild [PDF]

Research Journal of Pharmacognosy, 2020
Background and objectives: The bark of Alstonia boonei, known as stool wood, is sold in large quantities on the Ghanaian market. It is used for the treatment of numerous ailments including snake bites, worm infestation, malaria and rheumatic pains.
Emelia Oppong Bekoe*, Kirk Dodoo, Cindy Kitcher, Andrew Gordon, Samuel Frimpong-Manso, Gladys Schwinger   +5 more
doaj   +2 more sources

Herbs Used in Antimalarial Medicines: A Study in the Greater Accra Region of Ghana. [PDF]

Evid Based Complement Alternat Med, 2023
Background and Aim.Ghana is one of the many Sub‐Saharan African countries battling malaria. The disease is treated with orthodox medication as well as some home‐grown remedies, mainly from plants. This study sought to identify these local remedies being marketed, focusing on the active ingredients being used. Methods.
Nortey NND, Korsah S, Tagoe M, Apenteng JA, Owusu FA, Oppong J, Attah AE, Allotey S.   +7 more
europepmc   +2 more sources

Effect of Alstonia Boonei Stem Bark Extracts on the Activity of Liver Maker Enzymes in Rats Induced by Ccl4 [PDF]

مجلة بغداد للعلوم, 2022
This study investigated the outcome of Alstonia boonei stem bark on liver enzymes after inducing the Wistar albino rats with carbon tetrachloride (CCl4).
Victor E. Okpashi , Robert I. Uroko, Joy Ogana, A. Agbafor, C. P. Nwuke   +4 more
doaj   +3 more sources

Anti-Helicobacter pylori, anti-Inflammatory, and Antioxidant Activities of Trunk Bark of Alstonia boonei (Apocynaceae). [PDF]

Biomed Res Int, 2022
An ulcer is an erosion of the gastric mucosa that occurs following an imbalance between the aggression and protective factors and/or an infection with Helicobacter pylori (H. pylori). About 90‐100% of duodenal ulcers and 70‐80% of gastric ulcers are caused by H. pylori. The objective of this work was to evaluate in vitro the anti‐H. pylori activity and
Fagni Njoya ZL, Mbiantcha M, Djuichou Nguemnang SF, Matah Marthe VM, Yousseu Nana W, Madjo Kouam YK, Ngoufack Azanze E, Tsafack EG, Ateufack G.   +8 more
europepmc   +3 more sources