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A patient with anaphylaxis after alteplase infusion
Journal of Clinical Neuroscience, 2012 Anaphylaxis to alteplase is a rare but reported complication of intravenous thrombolysis. We report a patient with a documented episode of anaphylaxis that occurred following an initial bolus and a subsequent delayed infusion of alteplase for thrombolysis of acute ischaemic stroke.Robert J. Heddle, Robert J. Heddle, Simon A. Koblar, Simon A. Koblar, Jim Jannes, Jim Jannes, Andrew Lee, Andrew Lee, Jien N. Cheng +8 moreopenaire +4 more sourcesAlteplase for Hemodialysis Access Graft Thrombolysis
Journal of Vascular and Interventional Radiology, 2002 To evaluate the efficacy and safety of alteplase, a recombinant tissue plasminogen activator, in hemodialysis access graft thrombolysis.From November 1999 to May 2001, 68 episodes of occlusion in 50 grafts (in 49 patients) were included in the study.Kelekis Da, Constantinos T. Sofocleous, Clay Hinrichs, Allison Barone, Stanley H. Weiss, Philip Bahramipour, Elias Brountzos, Daniel Contractor +7 moreopenaire +3 more sourcesAlteplase: Pleural Effusion (Parapneumonic)
Hospital Pharmacy, 2003 Off-Label Drug Uses This Hospital Pharmacy feature is extracted from Off-Label DrugFacts, a quarterly publication available from Facts and Comparisons. Off-Label DrugFacts is a practitioner-oriented resource for information about specific FDA-unapproved drug uses.Joyce A. Generali, Dennis J. Cadaopenaire +2 more sourcesTenecteplase versus alteplase in acute ischaemic cerebrovascular events (TRACE-2): a phase 3, multicentre, open-label, randomised controlled, non-inferiority trial
The Lancet, 2023 Yongjun Wang, Shuya Li, Yuesong Pan, Hao Li, M. Parsons, B. Campbell, L. Schwamm, M. Fisher, F. Che, H. Dai, Deyang Li, Run-hui Li, Junhai Wang, Yilong Wang, Xing-hui Zhao, Zixiao Li, Huaguang Zheng, Yunyun Xiong, Xia Meng, Dong Wang, Shengli Chen, Dan Deng, Hong Zhang, Huisheng Chen, Hongwei Zhang, Yiping Wu, Hong Liu, Guozhi Lu, Liandong Zhao, Runxiu Zhu, Y. Liu, F. Yi, Jianhua Gao, Junfang Hao, Xueli Cai, Zhihui Duan, Hong Yu, Tong Wei, Yufeng Tang, Zhao Peng, Baochao Zhang, Yan Song, Xiaofei Chen, Yunlin Liu, Jing Liu, Weili Zhao, Xiu'e Wei, Qian Xue, Xuewen Liu, Yi Yang, Chuansheng Zhao, Jun Chen, Yibing Sui, Guizhi Sheng, Yun Zhang, Junyan Liu, Lianhua Zhang, Weiwei Wang, Zhiyong Guo, R. Hu, Guofang Chen, Zhigang Liang, Junbin Chen, Lei Xia, Z. Long +64 moresemanticscholar +1 more sourceIntravenous alteplase for acute ischaemic stroke [PDF]
Expert Opinion on Pharmacotherapy, 2005 Thrombolysis with intravenous alteplase is the only validated and approved treatment for acute ischaemic stroke. It is currently licensed for use within 3 h of stroke onset. This treatment improves functional outcome without increasing mortality, although it can initially cause a devastating intracerebral haemorrhage. Risk factors for this complication openaire +2 more sourcesWhat is the future for alteplase in stroke?
Inpharma Weekly, 1998 Limited clinical evidence supports the use of IV alteplase as thrombolytic therapy for patients with acute ischaemic stroke. Results from the US National Institute of Neurological Disorders and Stroke (NINDS) trial indicated that IV alteplase 0.9 mg/kg improved patient outcome when administered within 3 hours of onset of stroke symptoms.*Nevertheless ...openaire +2 more sourcesIntravenous tenecteplase compared with alteplase for acute ischaemic stroke in Canada (AcT): a pragmatic, multicentre, open-label, registry-linked, randomised, controlled, non-inferiority trial
The Lancet, 2022 B. Menon, B. Buck, Nishita Singh, Y. Deschaintre, M. Almekhlafi, S. Coutts, S. Thirunavukkarasu, H. Khosravani, R. Appireddy, F. Moreau, G. Gubitz, A. Tkach, L. Catanese, D. Dowlatshahi, G. Medvedev, J. Mandzia, A. Pikula, Jai Shankar, H. Williams, Thalia Shoshana Field, Alejandro Manosalva, Muzaffar M Siddiqui, A. Zafar, O. Imoukhuede, G. Hunter, A. Demchuk, Sachin Mishra, L. Gioia, S. Jalini, Carole Cayer, Stephen Phillips, E. Elamin, A. Shoamanesh, S. Subramaniam, M. Kate, G. Jacquin, Marie-Christine Camden, F. Benali, Ibrahim Alhabli, F. Bala, MacKenzie Horn, G. Stotts, Michael D. Hill, D. Gladstone, A. Poppe, A. Sehgal, Qiaoxian Zhang, B. Lethebe, Craig Doram, A. Ademola, M. Shamy, C. Kenney, T. Sajobi, R. Swartz, Abhilekh Srivastava, Ahmed M Aljammaz, Akintomide Femi Akindotun, A. Jin, Alexander Fraser, A. Khaw, Alexandru Lemnaru, A. Southwell, Alnar Ramji, A. Alvarado-Bolaños, Amr Mouminah, Amro B. Lahlouh, A. Yu, A. Alrohimi, A. Lavoie, A. Rogge, A. Micieli, A. L. Nguyen, Angelique Callaghan-Brown, Anita Florendo-Cumbermack, Ankur Wadhwa, A. Beaudoin, A. Cayley, A. Liddy, A. Trivedi, A. Katsanos, A. Shuaib, A. Butt, O. Bereznyakova, B. Beauchamp, Breane Mahlitz, B.R. Graham, B. Dewar, Bryce A. Durafourt, Caitlin E. Holtby, C. Jackson-Tarlton, Caitlyn Bockus, Caroline Stephenson, Camille Galloway, C. Odier, C. Deacon, C. Zerna, Chetan Vekhande, C. Bocti, C. Stapf, C. Hawkes, Christine Stables, C. Bogiatzi, C. Rodríguez, C. Candale-Radu, Colleen Murphy, C. Casserly, Daniel Fok, D. D. S. Boasquevisque, D. Wile, D. Volders, D. Sahlas, E. Shand, E. Cora, Eliane Di Battista, Eileen Stewart, E. Junk, Emma L. Harrison, É. Frenette, Ericka Teleg, Eslam Abdellah, E. Ghrooda, Farhan Akthar, F. Evoy, G. Klein, G. Maclean, G. Jickling, G. Hawthorne, G. Boyd, Greg Walker, G. Saposnik, H. L. Lau, Hanan Badr, H. Toma, H. Kalashyan, Hugo Marion-Moffet, Ian M Grant, Idris Fatakdawala, Isabelle Beaulieu‐Boire, Janice Williams, J. Brar, J. Rivest, Jeffrey Z. Wang, Jessica A. Dawe, J. Stang, J. Day, Jodi Miller, John J. Gorman, J. Hopyan, J. Lee, J. Kromm, K. Foster, K. Ratnayake, K. Perera, Karina Murray, Karla J. Ryckborst, Katie Lin, Kayla D. Sage, Keithan Sivakuma, Kelly MacDonald, K. Ng, Ketki Merchant, K. Khan, K. Ghavami, Kyra Johnston, L. Mai, Leah E. White, Lee Barratt, Linda Longpre, L. Crellin, L. Peeling, L. Piquette, L. Lomax, Mahsan Sadeghi, M. Kamra, Manuel Lavoie-April, M. Moores, M. Bullrich, M. McClelland, M. Salluzzi, Mark Wilcox, Mark Boulos, M. Marko, M. Boyko, Maude Lantagne-Hurtubise, M. Alhamid, Mays Shawawrah, Michael E Kelly, Michael Thorne, M. Bussiére, Ming Yin Dominc Tse, M. Benguzzi, Mukul Sharma, M. Horton, Nancy J. Newcommon, Nandy-Shelwine Simon, N. Parks, Nazeem Sultan, N. Markovic, N. Daneault, Noman Ishaque, P. Fairall, P. Kostyrko, P. Stys, P. Teal, P. Couillard, P. King-Azote, Quentin Collier, Rachel Epp, Radhika P. Nair, Raed A. Joundi, Rajive Jassal, Raphael Schneider, Reza Hosseini, Rosalie Bouchard, R. Whelan, S. R. Cooley, S. Sujanthan, S. Mansoor, S. Yip, S. Wasyliw, Sean W. Taylor, S. Friedman, Sharan K. Mann, S. Maley, Sherry Chiasson, Sherry Hu, S. Althubait, Shuhira Himed, Shuo Chen, Simerpreet S. Bal, S. Page, Stacey D Beck, Stephanie Woodroffe, Stephanie Reiter, S. V. Gaal, Steven R. Peters, S. Darvesh, Supriya Save, Susan E. Alcock, S. Piercey, S. Adam, Sylvie Gosselin, T. Fitzpatrick, T. Perron, Tim Stewart, T. Benstead, V. Naidoo, Wasan Abd Wahab, W. Oczkowski, William Kingston, W. Leduc, W. To, Yeyao Joe Yu, Zhongyu A. Liu, Ziad E. Aljundi +254 moresemanticscholar +1 more sourceTenecteplase versus alteplase for the management of acute ischaemic stroke in Norway (NOR-TEST 2, part A): a phase 3, randomised, open-label, blinded endpoint, non-inferiority trial
Lancet Neurology, 2022 C. E. Kvistad, H. Næss, B. H. Helleberg, T. Idicula, G. Hagberg, L. M. Nordby, Kristian N Jenssen, H. Tobro, Dag M Rörholt, K. Kaur, Agnethe Eltoft, K. Evensen, J. Haasz, Guruparan Singaravel, A. Fromm, L. Thomassen +15 moresemanticscholar +1 more source