Results 1 to 10 of about 2,071,373 (281)

Incidence of Hemorrhagic Complications among Patients Treated with Thrombolytic in Erbil City, Iraq [PDF]

Al-Anbar Medical Journal, 2020
Background: Recombinant tissue-type plasminogen activator is an option of treatment for suspected occlusive vascular thrombi and its sequel (transmural myocardial infarction, pulmonary embolism, and ischemic stroke). The most important concern associated
Ahmed F. Hammad, Imad T. Abdulhafed, Abdulsalam R. Awad   +2 more
doaj   +1 more source

Histone deacetylase inhibitor treatment increases coronary t-PA release in a porcine ischemia model. [PDF]

PLoS ONE, 2014
BACKGROUND: The expression of the tissue plasminogen activator gene can be affected by histone deacetylation inhibition and thus appears to be under epigenetic control.
Kristina Svennerholm, Niklas Bergh, Pia Larsson, Sverker Jern, Göran Johansson, Björn Biber, Michael Haney   +6 more
doaj   +1 more source

Results of two fibrinolytics in treatment of the early stage of empyema [PDF]

Zagazig University Medical Journal, 2023
Management of an early empyema is an important problem in thoracic surgery. As an alternative to surgical treatment empyema is in patients who developed early empyema , intra-pleural fibrinolysis has been used with favorable results.
amr tawfek, Mamdouh Elsharawy, Mohammad Ibrahim, Amr Mansour   +3 more
doaj   +1 more source

Peripheral embolization following thrombolytic therapy for acute ischemic stroke—a case report

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2020
Background Intravenous recombinant tissue plasminogen activator is the only golden approved medical therapy for acute ischemic stroke, guidelines for its injection relay on reducing or preventing associated hemorrhage as a side effect, yet hemorrhage is ...
Tamer Roushdy, Eman Hamid, Mai Fathy, Islam Bastawy, Hany Aref, Nevine El Nahas   +5 more
doaj   +1 more source

Plasma tissue plasminogen activator and plasminogen activator inhibitor-1 in hospitalized COVID-19 patients

Scientific Reports, 2021
Patients with coronavirus disease-19 (COVID-19) are at high risk for thrombotic arterial and venous occlusions. However, bleeding complications have also been observed in some patients.
Yu Zuo, Mark Warnock, Alyssa Harbaugh, Srilakshmi Yalavarthi, Kelsey Gockman, Melanie Zuo, Jacqueline A. Madison, Jason S. Knight, Yogendra Kanthi, Daniel A. Lawrence   +9 more
doaj   +1 more source

Fibrinolysis regulation by platelets retaining plasminogen and tissue-type plasminogen activator on their surface [PDF]

The Ukrainian Biochemical Journal, 2019
Platelets play a key role in hemostasis as cofactors of thrombin generation, fibrin polymerization centers­, and initiators of clot retraction, while their ability to modulate clot dissolution remains less understood.
T. Grinenko, О. Yusova, O. Revka, I. Patalakh, T. Yatsenko   +4 more
doaj   +1 more source

Inhibiting endogenous tissue plasminogen activator enhanced neuronal apoptosis and axonal injury after traumatic brain injury

Neural Regeneration Research, 2020
Tissue plasminogen activator is usually used for the treatment of acute ischemic stroke, but the role of endogenous tissue plasminogen activator in traumatic brain injury has been rarely reported.
Jun-Jie Zhao, Zun-Wei Liu, Bo Wang, Ting-Qin Huang, Dan Guo, Yong-Lin Zhao, Jin-Ning Song   +6 more
doaj   +1 more source

The effects of residual platelets in plasma on plasminogen activator inhibitor-1 and plasminogen activator inhibitor-1-related assays.

PLoS ONE, 2017
Due to controversial evidence in the literature pertaining to the activity of plasminogen activator inhibitor-1 in platelets, we examined the effects of residual platelets present in plasma (a potential pre-analytical variable) on various plasminogen ...
Marlien Pieters, Sunelle A Barnard, Du Toit Loots, Dingeman C Rijken   +3 more
doaj   +1 more source

In acute ischemic stroke patients with smoking incidence, are more women than men more likely to be included or excluded from thrombolysis therapy?

Women's Health, 2020
Background: Clinical factors associated with exclusion from recombinant tissue plasminogen activator in both men and women are not completely understood.
Oluyemi R Rotimi, Iretioluwa F Ajani, Alexandria Penwell, Shyyon Lari, Brittany Walker, Thomas I Nathaniel   +5 more
doaj   +1 more source

Leukocyte- and endothelial-derived microparticles: a circulating source for fibrinolysis

Haematologica, 2012
Background We recently assigned a new fibrinolytic function to cell-derived microparticles in vitro. In this study we explored the relevance of this novel property of microparticles to the in vivo situation.Design and Methods Circulating microparticles ...
Romaric Lacroix, Laurent Plawinski, Stéphane Robert, Loïc Doeuvre, Florence Sabatier, Sara Martinez de Lizarrondo, Anna Mezzapesa, Francine Anfosso, Aurelie S. Leroyer, Pascale Poullin, Noémie Jourde, Makon-Sébastien Njock, Chantal M. Boulanger, Eduardo Anglés-Cano, Françoise Dignat-George   +14 more
doaj   +1 more source