Tissue Plasminogen Activator in Psoriasis
Elevated levels of the serine proteinase plasminogen activator are observed in psoriatic lesions. In contrast to normal epidermis, lesional psoriatic epidermis contains primarily tissue type plasminogen activator (tPA) activity and much lower levels of urokinase type plasminogen activator (uPA) activity.
Jensen, P. J. +6 more
openaire +4 more sources
Reversal of cilioretinal artery occlusion with intra-arterial tissue plasminogen activator
Purpose: To present the reversal of a cilioretinal artery occlusion with the use of intra-arterial tissue plasminogen activator. Observations: A monocular 74 year old male presented with a cilioretinal artery occlusion.
Andrew J. McClellan +3 more
doaj +2 more sources
Activation of Bovine Plasminogen by the Plasminogen Activator in Animal Tissue
Summary1. The activation of bovine plasminogen by means of the plasminogen activator from pig heart tissue has been studied on heated fibrin and on casein.2. Small, but varying, amounts of activator can be extracted from crude activator powder during the experiment and interfere therefore with estimations on normal, plasminogen containing fibrin.3. The
T, ABE, T, ASTRUP
openaire +3 more sources
Content of Tissue Activator of Plasminogen in Monkey Tissues
SummaryThe content of the tissue activator of plasminogen in various organs from monkey is generally lower than in the corresponding human organs and approaches the concentration in the organs of other animals.
H R, ROBERTS, T, ASTRUP
openaire +3 more sources
Defibrotide, a polydeoxyribonucleotide of mammalian origin, has been shown to reduce the blood level of the plasminogen activator inhibitor, and so to increase the activity of tissue plasminogen activator without any adverse effect. A randomized, double-blind, placebo-controlled study has been done in 22 patients, 14 with peripheral vascular disease, 6
VIOLI, Francesco +5 more
openaire +4 more sources
Tissue Plasminogen Activator [PDF]
Coronary thrombolysis has been proved to be beneficial in the treatment of myocardial infarction. Much attention has been focused on tissue-type plasminogen activator (t-PA) as a fibrinolytic agent. This article will discuss the unique properties of t-PA and the role of the critical care nurse in providing the safe delivery of t-PA.
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Decreased Production of Tissue Plasminogen Activator in Endothelial Cells From Nasal Polyps. [PDF]
ABSTRACT Introduction Previous studies have demonstrated that chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by excessive fibrin deposition which is related to impaired production of tissue plasminogen activator(t‐PA) by epithelial cells.
Zhang QQ +9 more
europepmc +2 more sources
Prolonged elevations in haemostatic and rheological responses following psychological stress in low socioeconomic status men and women [PDF]
Low socioeconomic status (SES) and psychological stress are associated with increased risk of coronary heart disease, and both may influence haemostatic responses.
Lowe, G.D.O. +7 more
core +5 more sources
Effect of dsRNA on Mesangial Cell Synthesis of Plasminogen Activator Inhibitor Type 1 and Tissue Plasminogen Activator [PDF]
Background/Aims: Viral infections are a major problem worldwide and many of them are complicated by virally induced glomerulonephritides. Progression of kidney disease to renal failure is mainly attributed to the development of renal fibrosis ...
Wörnle, Markus +4 more
core +1 more source
Protease inhibitors prevent plasminogen-mediated, but not pemphigus vulgaris-induced, acantholysis in human epidermis [PDF]
Pemphigus is an autoimmune blistering disease of the skin and mucous membranes. It is caused by autoantibodies directed against desmosomes, which are the principal adhesion structures between epidermal keratinocytes.
Besch, R. +19 more
core +2 more sources

