Results 1 to 10 of about 17,466 (107)

Fibrinolysis vs. primary percutaneous coronary intervention for ST‐segment elevation myocardial infarction cardiogenic shock

ESC Heart Failure, 2021
Aims There are limited contemporary data on the use of initial fibrinolysis in ST‐segment elevation myocardial infarction cardiogenic shock (STEMI‐CS). This study sought to compare the outcomes of STEMI‐CS receiving initial fibrinolysis vs.
Saraschandra Vallabhajosyula, Dhiran Verghese, Malcolm R. Bell, Dennis H. Murphree, Wisit Cheungpasitporn, P. Elliott Miller, Shannon M. Dunlay, Abhiram Prasad, Gurpreet S. Sandhu, Rajiv Gulati, Mandeep Singh, Amir Lerman, Bernard J. Gersh, David R. Holmes Jr, Gregory W. Barsness   +14 more
doaj   +1 more source

Effect of acute alcohol intoxication on mortality, coagulation, and fibrinolysis in trauma patients.

PLoS ONE, 2021
BackgroundThe effect of alcohol on the outcome and fibrinolysis phenotype in trauma patients remains unclear. Hence, we performed this study to determine whether alcohol is a risk factor for mortality and fibrinolysis shutdown in trauma patients ...
Il-Jae Wang, Byung-Kwan Bae, Young Mo Cho, Suck Ju Cho, Seok-Ran Yeom, Sang-Bong Lee, Mose Chun, Hyerim Kim, Hyung-Hoi Kim, Sun Min Lee, Up Huh, Soo Young Moon   +11 more
doaj   +1 more source

Global coagulation assays to measure in vitro fibrinolysis

Thrombosis Update, 2021
(249/250 words): Introduction: Fibrinolysis is a critical component of hemostasis associated with poor outcomes if not treated early and effectively. Successful hemostasis management requires close fibrinolysis monitoring. The study aimed to compare the
Joao D. Dias, Ebrahim Shafizadeh, Jamie Leiriao, Jan Hartmann   +3 more
doaj   +1 more source

Fibrinolytic therapy use for ST-segment elevation myocardial infarction and long-term outcomes in China: 2-year results from the China Acute Myocardial Infarction Registry

BMC Cardiovascular Disorders, 2023
Background Data on fibrinolytic therapy use for ST-segment elevation myocardial infarction (STEMI) and long-term clinical outcomes in developing countries are limited.
Chao Wu, Ling Li, Shuqing Wang, Jianping Zeng, Jingang Yang, Haiyan Xu, Yanyan Zhao, Yang Wang, Wei Li, Chen Jin, Xiaojin Gao, Yuejin Yang, Shubin Qiao   +12 more
doaj   +1 more source

Investigation of the Relationship Between TAFI Plasma Levels and Hemorrhage in Patients with Crimean-Congo Hemorrhagic Fever and the Role of TAFI in the Disease Pathogenesis

Cerrahpaşa Medical Journal, 2021
Objective: Crimean-Congo hemorrhagic fever is a tick-borne viral infection presenting with fever and bleeding. Thrombin-activatable fibrinolysis inhibitor is a plasma procarboxypeptidase synthesized in the liver, causing downregulation of fibrinolysis ...
Hüsna Şengül Aşkın, Mehmet Parlak, Esra Laloğlu, Sinan Yılmaz, Lütfü Aşkın, Emine Parlak   +5 more
doaj   +1 more source

uPA-mediated plasminogen activation is enhanced by polyphosphate

Haematologica, 2020
Tissue plasminogen activator (tPA) and urokinase (uPA) differ in their modes of action. Efficient tPA-mediated plasminogen activation requires binding to fibrin.
Claire S. Whyte, Nicola J. Mutch
doaj   +1 more source

Point-of-care diagnosis and monitoring of fibrinolysis resistance in the critically ill: results from a feasibility study

Critical Care, 2023
Background Fibrinolysisis is essential for vascular blood flow maintenance and is triggered by endothelial and platelet release of tissue plasminogen activator (t-PA). In certain critical conditions, e.g.
Lucy A. Coupland, David J. Rabbolini, Jonathan G. Schoenecker, Philip J. Crispin, Jennene J. Miller, Tony Ghent, Robert L. Medcalf, Anders E. Aneman   +7 more
doaj   +1 more source

The state of the fibrinolytic system in HIV-infected pregnant women and parturient women with thrombohemorrhagic risk factors

Репродуктивная эндокринология, 2020
Purpose of the study: to explore the status of the fibrinolytic system in HIV-infected pregnant women and parturient women. Materials and methods. 120 HIV-positive pregnant women with risk factors of thrombohemorrhagic complications were examined.
С. Є. Савченко, О. І. Гервазюк, Л. М. Онищик, Ю. С. Мудра, Г. Б. Бойко   +4 more
doaj   +1 more source

Increased thrombin activatable fibrinolysis inhibitor activity is associated with hypofibrinolysis in dogs with sepsis

Frontiers in Veterinary Science, 2023
IntroductionDisorders of coagulation are well-recognized in dogs with sepsis, but data regarding fibrinolysis disorders are limited. We aimed to characterize fibrinolysis in dogs with sepsis compared to healthy controls.
Katherine E. Sotos, Robert Goggs, Alyssa P. Stablein, Marjory B. Brooks   +3 more
doaj   +1 more source

Endogenous fibrinolysis inhibitors in acute coronary syndrome

American Heart Journal Plus, 2021
Patients with acute coronary syndrome have a high residual risk of ischemic events despite current treatment methods, both invasive and antithrombotic strategies. The strategy of very early revascularization although has been suggested to improve patient
Baskaran Chandrasekar
doaj   +1 more source