Real-Time Fibrinolysis Monitoring of Plasma Annular Clots [PDF]
BiomoleculesFibrinolysis assessment is critical for diagnosing and managing clinical blood disorders. Currently available viscoelastic testing platforms provide an overview of global coagulation and fibrinolysis profiles but lack fibrinolysis specific assessment of ...
Andres Prieto Trujillo +3 more
doaj +2 more sources
Is “Physiological Lysis” in Viscoelastometry a Plasmin-Mediated Process? [PDF]
DiagnosticsViscoelastic testing (VET) is widely used to guide hemostatic therapy in patients with coagulopathy. One important application is the detection of fibrinolysis, defined as a reduction in clot amplitude after maximum clot firmness (MCF), quantified as ...
Anikó Smudla +4 more
doaj +2 more sources
Assessment of Fibrinolysis in Sepsis Patients with Urokinase Modified Thromboelastography
PLoS ONE, 2015 IntroductionImpairment of fibrinolysis during sepsis is associated with worse outcome. Early identification of this condition could be of interest. The aim of this study was to evaluate whether a modified point-of-care viscoelastic hemostatic assay can ...
Massimo Cressoni, Alessandro Protti
exaly +2 more sources
An exploratory plasma-based functional assay for phenotypic characterization of fibrinolysis in dysfibrinogenemia [PDF]
Research and Practice in Thrombosis and HaemostasisBackground: Congenital dysfibrinogenemia exhibits heterogeneous clinical phenotypes, ranging from bleeding to thrombosis. However, conventional fibrinogen assays primarily evaluate clot formation alone.
Atsuo Suzuki +7 more
doaj +2 more sources
Outcomes according to timely or delayed primary percutaneous coronary intervention or fibrinolysis in a national registry of patients with ST-segment elevation myocardial infarction [PDF]
Open HeartBackground Time to reperfusion is a predictor of long-term outcomes in ST-segment elevation myocardial infarction (STEMI). Timely primary percutaneous coronary intervention (PCI) is the preferred strategy recommended by guidelines.
Peter Kearney +14 more
doaj +2 more sources
Neutrophil extracellular traps formation is associated with impaired clot retraction and fibrinolysis in asthma [PDF]
Frontiers in ImmunologyBackgroundAsthma is associated with an elevated risk of venous thromboembolism and pulmonary embolism; its etiology is not completely understood.ObjectiveThis study was designed to investigate whether the formation of neutrophil extracellular traps (NET)
Tomasz Misztal +5 more
doaj +2 more sources
ESC Heart Failure, 2021 Aims There are limited contemporary data on the use of initial fibrinolysis in ST‐segment elevation myocardial infarction cardiogenic shock (STEMI‐CS). This study sought to compare the outcomes of STEMI‐CS receiving initial fibrinolysis vs.
Saraschandra Vallabhajosyula +14 more
doaj +1 more source
Effect of acute alcohol intoxication on mortality, coagulation, and fibrinolysis in trauma patients.
PLoS ONE, 2021 BackgroundThe effect of alcohol on the outcome and fibrinolysis phenotype in trauma patients remains unclear. Hence, we performed this study to determine whether alcohol is a risk factor for mortality and fibrinolysis shutdown in trauma patients ...
Il-Jae Wang +11 more
doaj +1 more source
Global coagulation assays to measure in vitro fibrinolysis
Thrombosis Update, 2021 (249/250 words): Introduction: Fibrinolysis is a critical component of hemostasis associated with poor outcomes if not treated early and effectively. Successful hemostasis management requires close fibrinolysis monitoring. The study aimed to compare the
Joao D. Dias +3 more
doaj +1 more source
BMC Cardiovascular Disorders, 2023 Background Data on fibrinolytic therapy use for ST-segment elevation myocardial infarction (STEMI) and long-term clinical outcomes in developing countries are limited.
Chao Wu +12 more
doaj +1 more source