Results 21 to 30 of about 17,466 (107)

Bleeding Disorders in Primary Fibrinolysis

, 2021
Fibrinolysis is a complex enzymatic process aimed at dissolving blood clots to prevent vascular occlusions. The fibrinolytic system is composed of a number of cofactors that, by regulating fibrin degradation, maintain the hemostatic balance.
Marco Zaffanello, Massimo Franchini, Pier Mannuccio Mannucci   +2 more
core   +1 more source

Tissue factor-expressing monocytes inhibit fibrinolysis through a TAFI-mediated mechanism, and make clots resistant to heparins

Haematologica, 2009
Background Thrombin is the main activator of the fibrinolysis inhibitor TAFI (thrombin activatable fibrinolysis inhibitor) and heightened clotting activation is believed to impair fibrinolysis through the increase of thrombin activatable fibrinolysis ...
Fabrizio Semeraro, Concetta T. Ammollo, Nicola Semeraro, Mario Colucci   +3 more
doaj   +1 more source

Fibrin Breakdown Assay

Bio-Protocol, 2020
Fibrinolysis is an integral part of the matrix remodeling process that contributes to tissue repair. Fibrin clots are broken down during fibrinolysis in a controlled process.
Jiayue Ling, Connor Blair, George Baillie   +2 more
doaj   +1 more source

Plasminogen receptors and fibrinolysis

, 2021
The ability of cells to promote plasminogen activation on their surfaces is now well recognized, and several distinct cell surface proteins have been demonstrated to function as plasminogen receptors.
Miles, Lindsey A., Malgorzata Wilczynska, Robert J. Parmer, Miles, Lindsey A.,, Ny, Tor, Ny, Lina, Shen, Yue, Pietrzykowska, Malgorzata, Ny, Lina,, Yue Shen, Tor Ny, Parmer, Robert J.,, Shen, Yue,, Pietrzykowska, Malgorzata,, Ny, Tor,, Lina Ny, Parmer, Robert J., Lindsey A. Miles   +17 more
core   +1 more source

A study to compare fibrinolytic therapy versus primary percutaneous coronary intervention in ST-segment elevation myocardial infarction in a tertiary care hospital

National Journal of Physiology, Pharmacy and Pharmacology, 2022
Background: ST-segment elevation myocardial infarction (STEMI) is the most dramatic manifestation of coronary artery disease, acute STEMI is a clinical syndrome defined by characteristic symptoms of myocardial ischemia in association with persistent ...
Anupama M, Sharath Kumar JV, Shetty GG
doaj   +1 more source

Thrombin activatable fibrinolysis inhibitor como preditor de sangramento no transplante hepático: estudo piloto observacional

Revista Brasileira de Terapia Intensiva
RESUMO Objetivo: Correlacionar os níveis de thrombin activatable fibrinolysis inhibitor no pós-operatório imediato e com 24 horas de pós-operatório com o volume de sangramento tansoperatório.
Wagner Luis Nedel, Edison Moraes Rodrigues Filho, Alessandro Comarú Pasqualotto   +2 more
doaj   +1 more source

Angiographic outcomes in STEMI patients receiving fibrinolysis with guideline directed optimal antithrombotic therapy

Indian Heart Journal, 2021
STEMI is a major public health problem requiring timely reperfusion. Fibrinolysis remains prevalent reperfusion strategy where timely primary percutaneous coronary intervention (PCI) cannot be performed.
Shazia Durdana, Mohammad Azharuddin Malik, Asif Hasan, M.U. Rabbani   +3 more
doaj   +1 more source

Halo fluorescence fibrinolysis test: a novel quantitative assay to evaluate fibrinolysis on established plasma clots

Research and Practice in Thrombosis and Haemostasis
Background: Fibrinolysis is essential for dissolving blood clots and maintaining hemostasis. This process is primarily mediated by tissue-type plasminogen activator, which converts plasminogen into plasmin, thereby breaking down fibrin clots. Traditional
Zikou Liu, Orr Zaacks, Be’eri Niego, Robert L. Medcalf   +3 more
doaj   +1 more source

Fibrin Clot Formation and Lysis in Plasma

Methods and Protocols, 2020
Disturbance in the balance between fibrin formation and fibrinolysis can lead to either bleeding or thrombosis; however, our current routine coagulation assays are not sensitive to altered fibrinolysis.
Julie Brogaard Larsen, Anne-Mette Hvas
doaj   +1 more source

A novel serine protease secreted by medicinal maggots enhances plasminogen activator-induced fibrinolysis. [PDF]

PLoS ONE, 2014
Maggots of the blowfly Lucilia sericata are used for the treatment of chronic wounds. As haemostatic processes play an important role in wound healing, this study focused on the effects of maggot secretions on coagulation and fibrinolysis.
Mariena J A van der Plas, Anders S Andersen, Sheresma Nazir, Nico H van Tilburg, Peter R Oestergaard, Karen A Krogfelt, Jaap T van Dissel, Paul J Hensbergen, Rogier M Bertina, Peter H Nibbering   +9 more
doaj   +1 more source