Results 1 to 10 of about 15,447,907 (346)

D-dimer as a biomarker for assessment of COVID-19 prognosis: D-dimer levels on admission and its role in predicting disease outcome in hospitalized patients with COVID-19.

PLoS ONE, 2021
IntroductionCoronavirus Disease 2019 is a primarily respiratory illness that can cause thrombotic disorders. Elevation of D-dimer is a potential biomarker for poor prognosis in COVID-19, though optimal cutoff value for D-dimer to predict mortality has ...
Ayusha Poudel, Yashasa Poudel, Anurag Adhikari, Barun Babu Aryal, Debika Dangol, Tamanna Bajracharya, Anil Maharjan, Rakshya Gautam   +7 more
doaj   +2 more sources

D-dimer testing: A narrative review

Advances in Clinical Chemistry, 2023
D-dimer containing species are soluble fibrin degradation products derived from plasmin-mediated degradation of cross-linked fibrin, i.e., 'D-dimer'. D-dimer can hence be considered a biomarker of in vivo activation of both coagulation and fibrinolysis, the leading clinical application in daily practice of which is ruling out venous thromboembolism ...
Wauthier, L., Favresse, J., Hardy, M., Douxfils, J., Le Gal, G., Roy, P. M., van Es, N., Ay, C., ten Cate, H., Lecompte, T., Lippi, G., Mullier, F.   +11 more
openaire   +6 more sources

The poor prognosis and influencing factors of high D-dimer levels for COVID-19 patients

Scientific Reports, 2021
To explore the value, and influencing factors, of D-dimer on the prognosis of patients with COVID-19. A total of 1,114 patients with confirmed COVID-19 who were admitted to three designated COVID-19 hospitals in Wuhan, China from January 18, 2020, to ...
Xiaokang He, Fei Yao, Jie Chen, Yan Wang, Xiangming Fang, Xuan Lin, Hui Long, Qiang Wang, Qingming Wu   +8 more
doaj   +2 more sources

Short- and long-term risk stratification in acutely ill medical patients by implementing D-dimer in the emergency setting – A prospective cohort study [PDF]

American Heart Journal Plus
Objective: D-dimer testing is commonly used in emergency departments (EDs) to rule out thromboembolic events. However, elevated D-dimer levels may also be associated with an increased risk of mortality, independent of thromboembolism.
Andrea Kornfehl, Roman Brock, Julia Oppenauer, Felix Eibensteiner, Christoph Veigl, Marco Neymayer, Karolina Valentova, Alexandra Julia Lipa, Markus Müller, Tim Dreier, Philip Verdonck, Patrick Mucher, Thomas Perkmann, Helmuth Haslacher, Oliver Schlager, Sebastian Schnaubelt   +15 more
doaj   +2 more sources

The D‐dimer assay [PDF]

American Journal of Hematology, 2019
AbstractD‐dimer is an indirect marker of fibrinolysis and fibrin turnover; this molecule exhibits unique properties as a biological marker of hemostatic abnormalities as well as an indicator of intravascular thrombosis. D‐dimer is a soluble fibrin degradation product that results from the systematic degradation of vascular thrombi through the ...
Eric D. Johnson, John C. Schell, George M. Rodgers   +2 more
openaire   +3 more sources

Admission D-dimer levels, D-dimer trends, and outcomes in COVID-19 [PDF]

Thrombosis Research, 2020
Observational data suggest an acquired prothrombotic state may contribute to the pathophysiology of COVID-19. These data include elevated D-dimers observed among many COVID-19 patients. We present a retrospective analysis of admission D-dimer, and D-dimer trends, among 1065 adult hospitalized COVID-19 patients, across 6 New York Hospitals.
Naymagon, Leonard, Zubizarreta, Nicole, Feld, Jonathan, van Gerwen, Maaike, Alsen, Mathilda, Thibaud, Santiago, Kessler, Alaina, Venugopal, Sangeetha, Makki, Iman, Qin, Qian, Dharmapuri, Sirish, Jun, Tomi, Bhalla, Sheena, Berwick, Shana, Christian, Krina, Mascarenhas, John, Dembitzer, Francine, Moshier, Erin, Tremblay, Douglas   +18 more
openaire   +3 more sources

D‐Dimer: A Mediator of the Association Between Lymphocyte and Dissemination of Pulmonary Tuberculosis: A Retrospective Cohort Study [PDF]

The Clinical Respiratory Journal
Introduction This study aimed to examine whether D‐dimer and lymphocyte counts predict the risk of concurrent pulmonary tuberculosis (PTB) and extrapulmonary tuberculosis (EPTB) and to identify critical thresholds for clinical use.
Yujun Lin, Di Wu, Xiaohong Chen, Lujing Jiang, Yiming Zeng   +4 more
doaj   +2 more sources

Dynamic changes of D-dimer and neutrophil-lymphocyte count ratio as prognostic biomarkers in COVID-19

Respiratory Research, 2020
Background Since December 2019, the outbreak of COVID-19 caused a large number of hospital admissions in China. Many patients with COVID-19 have symptoms of acute respiratory distress syndrome, even are in danger of death.
Wenjing Ye, Guoxi Chen, Xiaopan Li, Xing Lan, Chen Ji, Min Hou, Di Zhang, Guangwang Zeng, Yaling Wang, Cheng Xu, Weiwei Lu, Ruolin Cui, Yuyang Cai, Hai Huang, Ling Yang   +14 more
doaj   +2 more sources

D-dimer for risk stratification and antithrombotic treatment management in acute coronary syndrome patients: asystematic review and metanalysis

Thrombosis Journal, 2021
Background Data on the prognostic role of D-dimer in patients with acute coronary syndrome (ACS) are controversial. Our aim was to summarize current evidence on the association between D-dimer levels and short/long-term poor prognosis of ACS patients. We
Flavio Giuseppe Biccirè, Alessio Farcomeni, Carlo Gaudio, Pasquale Pignatelli, Gaetano Tanzilli, Daniele Pastori   +5 more
doaj   +2 more sources

How we manage a high D-dimer

Haematologica, 2023
D-dimer, a soluble fibrin degradation product that originates from plasmin-induced degradation of cross-linked fibrin, is an important biomarker of coagulation activation and secondary fibrinolysis that is routinely used to rule out venous ...
Massimo Franchini, D. Focosi, Mario Piergiulio Pezzo, P. M. Mannucci   +3 more
semanticscholar   +1 more source