Results 41 to 50 of about 13,822,372 (257)

Reliability of D-Dimer test results in deciding the necessity of performing CTA in high risk population to establish the diagnosis of PE

The Egyptian Journal of Radiology and Nuclear Medicine, 2016
Purpose: To evaluate the reliability of D-Dimer test results in the diagnosis of PE in high risk patients. Patients and methods: This prospective study was conducted on 98 patients. Mean age was 50 years; age range was 17–88 years. All patients underwent
Saher Ebrahim Taman, Eman Muhammad Abdelslam, Nermin Yousef Aboelkheir   +2 more
doaj   +1 more source

Clinical Correlation between Plasma D-Dimer Level and Long-Term Neurological Outcome in Acute Ischemic Stroke [PDF]

Journal of Neurocritical Care, 2015
Background: D-dimer is a reliable and sensitive index of fibrin deposition and stabilization. It is well known that D-dimer levels are significantly associated with cardioembolic infarction and are elevated during the acute phase of cerebral infarction ...
Jung-Min So, Tae-Won Kim, In-Uk Song, Jeong-Wook Park, Sung-Woo Chung, Kwang-Soo Lee   +5 more
doaj   +1 more source

Relationship between baseline D-dimer and prognosis in Japanese patients with venous thromboembolism: Insights from the J’xactly study

Frontiers in Cardiovascular Medicine, 2023
BackgroundD-dimer is a biomarker of fibrin production and degradation, and changes in D-dimer concentration suggest fibrin clot formation, which is associated with thromboembolism and hypercoagulable states.
Shohei Migita, Yasuo Okumura, Ikuo Fukuda, Mashio Nakamura, Norikazu Yamada, Morimasa Takayama, Hideaki Maeda, Takeshi Yamashita, Takanori Ikeda, Makoto Mo, Tsutomu Yamazaki, Atsushi Hirayama   +11 more
doaj   +1 more source

The association between blood coagulation activity and lung function: a population-based study [PDF]

, 2010
<p><b>Background:</b> Increased in susceptibility to thrombotic disease may be associated with lower lung function. If causal, this association may suggest an area for development of new interventions for lung disease.
Lowe, G.D.O., Lorna Clark, Clark, L., Sarah A Lewis, Andrew W Fogarty, Tricia M McKeever, John Britton, Fogarty, A.W., Lewis, S.A., Gordon D O Lowe, Britton, J., Sarah A. Lewis, McKeever, T.M., Gordon D. O. Lowe, Tricia M. McKeever, Reitsma, P.H., Andrew W. Fogarty   +16 more
core   +2 more sources

Peripherally inserted central venous catheter in upper extremities leads to an increase in D-dimer and deep vein thrombosis in lower extremities

Thrombosis Journal, 2021
Background The purpose of this study is to elucidate the association between peripherally inserted central venous catheter (PICC) in upper extremities and lower extremity deep venous thrombosis (LEDVT) by observing the changes in D-dimer.
Wanli Liu, Lianxiang He, Wenjing Zeng, Liqing Yue, Jie Wei, Shuangshuang Zeng, Xiang Wang, Zhicheng Gong   +7 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

D-Dimer Is a Predictive Factor of Cancer Therapeutics-Related Cardiac Dysfunction in Patients Treated With Cardiotoxic Chemotherapy

Frontiers in Cardiovascular Medicine, 2022
BackgroundD-dimer is a sensitive biomarker for cancer-associated thrombosis, but little is known about its significance on cancer therapeutics-related cardiac dysfunction (CTRCD).MethodsConsecutive 169 patients planned for cardiotoxic chemotherapy were ...
Masayoshi Oikawa, Daiki Yaegashi, Tetsuro Yokokawa, Tomofumi Misaka, Takamasa Sato, Takashi Kaneshiro, Atsushi Kobayashi, Akiomi Yoshihisa, Kazuhiko Nakazato, Takafumi Ishida, Yasuchika Takeishi   +10 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

D-dimer for risk stratification and antithrombotic treatment management in acute coronary syndrome patients: asystematic review and metanalysis

Thrombosis Journal, 2021
Background Data on the prognostic role of D-dimer in patients with acute coronary syndrome (ACS) are controversial. Our aim was to summarize current evidence on the association between D-dimer levels and short/long-term poor prognosis of ACS patients. We
Flavio Giuseppe Biccirè, Alessio Farcomeni, Carlo Gaudio, Pasquale Pignatelli, Gaetano Tanzilli, Daniele Pastori   +5 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source