Results 61 to 70 of about 10,603,245 (304)
Elevated plasma D-dimer levels correlate with long term survival of gastric cancer patients. [PDF]
PLoS ONE, 2014 BACKGROUND: Increasing evidence indicated plasma D-dimer could be regarded as a marker in cancers, however, its role in gastric cancer is still largely unknown.
Long Liu +8 more
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2023 BackgroundShock is associated with the activation of the coagulation and fibrinolytic system, and D-dimer is the degradation product of cross-linked fibrin.
Yi Jiang +8 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
D-Dimer Combined with Fibrinogen Predicts the Risk of Venous Thrombosis in Fracture Patients
Emergency Medicine International, 2020 Objective. While D-dimer can successfully diagnose venous thrombosis due to its excellent negative predictive value (NPV), it cannot be used to detect venous thromboembolism (VTE) because of its low positive predictive value (PPV).
Chaohui Lin +5 more
doaj +1 more source
Clinical Medicine, 2019 Editor – I enjoyed the article by Dutton et al [1][1] who described the process of retrospectively creating an age adjusted D-dimer for the assay they used. The use of an age-adjusted cut-off has been successfully tested across a range of D-dimer assays, although a different Hemos assay was ...
openaire +2 more sources
A Retrospective Analysis of Serum D-Dimer Levels for the Exclusion of Acute Aortic Dissection
, 2022 Tony Zitek,1 Mani Hashemi,2 Sara Zagroba,2 Valori H Slane2 1Department of Emergency Medicine, Mount Sinai Medical Center, Miami Beach, FL, USA; 2Department of Emergency Medicine, Kendall Regional Medical Center, Miami, FL, USACorrespondence: Tony Zitek ...
Zitek T, Slane VH, Hashemi M, Zagroba S
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
F1000Research, 2023 Background: Coronavirus disease 2019 (COVID-19) is a global pandemic. Coagulopathy is one of the most common complications characterized by increased D-dimer level. We aimed to investigate the dose-response relationship between elevated D-dimer level and
Ponco Birowo +7 more
doaj +1 more source
International Journal of Critical Illness and Injury Science, 2014 Pulmonary embolism, Deep Vein Thrombosis (DVT) and Disseminated intravascular coagulation (DIC) are important sources of mortality and morbidity in intensive care unit (ICU). And every time D-dimer remains the the commonest investigation. Many times D-dimer is erroneously considered as a diagnostic test in above mentioned conditions. Its interpretation
Sathe, Prachee M., Patwa, Urvil D.
openaire +3 more sources