Results 81 to 90 of about 15,447,907 (346)

Clinical Correlation between Plasma D-Dimer Level and Long-Term Neurological Outcome in Acute Ischemic Stroke [PDF]

Journal of Neurocritical Care, 2015
Background: D-dimer is a reliable and sensitive index of fibrin deposition and stabilization. It is well known that D-dimer levels are significantly associated with cardioembolic infarction and are elevated during the acute phase of cerebral infarction ...
Jung-Min So, Tae-Won Kim, In-Uk Song, Jeong-Wook Park, Sung-Woo Chung, Kwang-Soo Lee   +5 more
doaj   +1 more source

D-Dimer Is a Predictive Factor of Cancer Therapeutics-Related Cardiac Dysfunction in Patients Treated With Cardiotoxic Chemotherapy

Frontiers in Cardiovascular Medicine, 2022
BackgroundD-dimer is a sensitive biomarker for cancer-associated thrombosis, but little is known about its significance on cancer therapeutics-related cardiac dysfunction (CTRCD).MethodsConsecutive 169 patients planned for cardiotoxic chemotherapy were ...
Masayoshi Oikawa, Daiki Yaegashi, Tetsuro Yokokawa, Tomofumi Misaka, Takamasa Sato, Takashi Kaneshiro, Atsushi Kobayashi, Akiomi Yoshihisa, Kazuhiko Nakazato, Takafumi Ishida, Yasuchika Takeishi   +10 more
doaj   +1 more source

Standardizing the d-dimer Assay: Proposing the d-dimer International Managed Ratio [PDF]

Clinical Chemistry, 2015
To the Editor: The d-dimer assay currently lacks standardization, since each manufacturer uses a different cutoff to define an abnormal value. The existence of at least 6 commonly used assays—all with differing units and cutoffs—leads to confusion among practitioners.
Zachary P, Kahler, Jeffrey A, Kline
openaire   +2 more sources

D‐dimer Triage for COVID‐19 [PDF]

Academic Emergency Medicine, 2020
Coagulopathy and elevated D-dimer levels were recognized as prognostic factors early in Wuhan, China as accompanying more severe COVID-19 patient cases. We sought to determine the accuracy of normal vs elevated D-dimer blood levels at presentation, day 1, and on day 3 for predicting 28-day survival in a large cohort of consecutive PCR-proven COVID-19 ...
Li, Chenghong, Hu, Bingzhu, Zhang, Zhu, Qin, Wei, Zhu, Ziyang, Zhai, Zhenguo, Davidson, Bruce L., Wang, Chen   +7 more
openaire   +2 more sources

Plasma D-dimer concentration in patients with systemic sclerosis [PDF]

, 2006
Background Systemic sclerosis (SSc) is an autoimmune disorder of the connective tissue characterized by widespread vascular lesions and fibrosis. Little is known so far on the activation of the hemostatic and fibrinolytic systems in SSc, and most ...
LIPPI, Giuseppe, Volpe A, Caramaschi P, SALVAGNO, GIAN LUCA, MONTAGNANA, Martina, GUIDI, Giancesare   +5 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

The Diagnostic Efficacy of Age-Adjusted D-Dimer Cutoff Value and Pretest Probability Scores for Deep Venous Thrombosis

Clinical and Applied Thrombosis/Hemostasis, 2019
This study seeks to evaluate the diagnostic value of D-Dimer Plus and Innovance D-Dimer as well as the age-adjusted cutoff value for D-dimer detection in combination with 4 pretest probability (PTP) scores for deep venous thrombosis (DVT). A total of 688
Junxun Li MM, MHA, Fan Zhang BM, Chujia Liang MBBMS, Zhuangjian Ye BM, Shaoqian Chen MM, Jing Cheng MM   +5 more
doaj   +1 more source

Profile of D-dimer in Uncomplicated Pregnancy

Indonesian Journal of Obstetrics and Gynecology, 2019
Objective: To obtain the profile of D-dimer in uncomplicated pregnancy. Methods: A cross sectional study was done on 90 uncomplicated pregnant women consisted of 30 women in each trimester and 30 healthy, nonpregnant women as control group from July ...
Rahajuningsih Dharma, Mercy T. Panjaitan, Kanadi Sumapradja, Rianto Setiabudy   +3 more
doaj   +1 more source

Clinical significance of D-dimer levels during acute period in ischemic stroke

Thrombosis Journal, 2023
Background Initial D-dimer level is a well-known prognostic parameter in patients with acute ischemic stroke (AIS). However, there have been no studies on the clinical significance of follow-up D-dimer levels.
Ki-Woong Nam, Hyung-Min Kwon, Yong-Seok Lee   +2 more
doaj   +1 more source