Results 41 to 50 of about 62,276 (286)

Fibrinolysis in Dogs with Intracavitary Effusion: A Review

Animals, 2022
Physiologic fibrinolysis is a localized process in which stable fibrin strands are broken down by plasmin in response to thrombosis. Plasmin activation can also take place separately from the coagulation process, resulting in pathologic fibrinolysis ...
Andrea Zoia, Michele Drigo, Marco Caldin, Paolo Simioni, Christine J. Piek   +4 more
doaj   +1 more source

Changes in Immune‐Inflammation Status and Prognosis in Pregnancy‐Related Cerebral Venous Thrombosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Distinguishing pathological changes from physiological adaptations in pregnancy‐related cerebral venous thrombosis (CVT) is clinically challenging. This study aimed to characterize coagulation, immune‐inflammation, and dehydration status in these patients and assess their prognostic value.
Xiaoming Zhang, Zilin Xu, Ran Duan, Chunxiao Lu, Da Zhou, Chen Zhou, Ran Meng, Xunming Ji   +7 more
wiley   +1 more source

Laboratory Evaluation Of Patients With Undiagnosed Bleeding Disorders

, 2016
The evaluation of patients with a bleeding tendency represents a challenge as the routinely available tests for evaluating bleeding disorders are limited, complicating the laboratory determination of the clinically observed bleeding tendency. As a result,
Santiago-Bassora, Fernanda Dutra, Paula, Erich Vinicius de, Annichino-Bizzacchi, Joyce M, Quaino, Susan Kelly Picoli, Orsi, Fernanda Andrade, Alves, Graziela Silveira Araújo, Montalvão, Silmara Aparecida Lima   +6 more
core   +2 more sources

Patient‐Derived 3D Heart‐On‐a‐Chip Model of Dilated Cardiomyopathy With Embedded Bead‐Based Mapping of Tissue Contractility

Advanced Healthcare Materials, EarlyView.
A heart‐on‐a‐chip model of dilated cardiomyopathy is developed from patient‐derived induced pluripotent stem cells. The model recapitulates key disease phenotypes and enables functional assessment through integrated bead‐based tracking and pillar deflection measurements.
Ali Mousavi, Ludovic Mouttet, Shihao Cui, Yasaman Hekmatnia, Mehran Mottahedi, Ida Derish, Naimeh Rafatian, Mark Aurousseau, Gregor Andelfinger, Renzo Cecere, Houman Savoji   +10 more
wiley   +1 more source

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

Hemostatic Alterations in Patients With Cirrhosis: From Primary Hemostasis to Fibrinolysis. [PDF]

, 2020
In the setting of liver cirrhosis (LC), profound hemostatic changes occur, which affect primary hemostasis, coagulation, and fibrinolysis. They involve prohemorrhagic and prothrombotic alterations at each of these steps.
Bertaggia Calderara, Debora, Maxime G. Zermatten, Aliotta, Alessandro, De Gottardi, Andrea, Zermatten, Maxime G, Montserrat Fraga, Alessandro Aliotta, Guido Stirnimann, Fraga, Montserrat, Moradpour, Darius, Andrea De Gottardi, Stirnimann, Guido, Alberio, Lorenzo, Darius Moradpour, Debora Bertaggia Calderara, Lorenzo Alberio   +15 more
core   +1 more source

Light‐Driven Quadrupedal Walking Biohybrid Robot With Antagonistic Muscle‐Rings and Inclined Joints

Advanced Robotics Research, EarlyView.
This work presents a light‐driven quadrupedal walking biohybrid robot powered by antagonistic muscle‐rings that achieve alternating walking gait. Optical training improved reproducibility of cultured muscle tissues, while caffeine treatment enhanced contractile force.
Shotaro Saito, Byeongwook Jo, Tomohiro Morita, Shota Noda, Minghao Nie, Shoji Takeuchi   +5 more
wiley   +1 more source

Utility of fibrinolysis enhanced viscoelastic assays to evaluate fibrinolysis disorders in critically ill adults with severe infection: a scoping review

Annals of Intensive Care
Background: Acutely infected critically ill patients develop coagulopathies and perturbations to the fibrinolysis system that manifest as immunothrombosis.
Matthew Self, Lucy A. Coupland, Anders Aneman   +2 more
doaj   +1 more source

Hypofibrinolysis in type 2 diabetes and its clinical implications: from mechanisms to pharmacological modulation

Cardiovascular Diabetology, 2021
A prothrombotic state is a typical feature of type 2 diabetes mellitus (T2DM). Apart from increased platelet reactivity, endothelial dysfunction, hyperfibrinogenemia, and hypofibrinolysis are observed in T2DM.
Agata Hanna Bryk-Wiązania, Anetta Undas
doaj   +1 more source

Clinical Significance of the Fibrinolytic Mechanism : Dynamic Equivalent Mechanism between Blood Coagulation and Fibrinolysis [PDF]

, 1984
P(論文)Mammalian blood contains two opposite enzymatic systems. One is the coagulation system capable of clot formation of blood and the other is the fibrinolytic system capable of dissolving blood clots.
安河内, 太郎, 21756
core