Results 41 to 50 of about 47,940 (267)

Tissue factor-expressing monocytes inhibit fibrinolysis through a TAFI-mediated mechanism, and make clots resistant to heparins

Haematologica, 2009
Background Thrombin is the main activator of the fibrinolysis inhibitor TAFI (thrombin activatable fibrinolysis inhibitor) and heightened clotting activation is believed to impair fibrinolysis through the increase of thrombin activatable fibrinolysis ...
Fabrizio Semeraro, Concetta T. Ammollo, Nicola Semeraro, Mario Colucci   +3 more
doaj   +1 more source

A study to compare fibrinolytic therapy versus primary percutaneous coronary intervention in ST-segment elevation myocardial infarction in a tertiary care hospital

National Journal of Physiology, Pharmacy and Pharmacology, 2022
Background: ST-segment elevation myocardial infarction (STEMI) is the most dramatic manifestation of coronary artery disease, acute STEMI is a clinical syndrome defined by characteristic symptoms of myocardial ischemia in association with persistent ...
Anupama M, Sharath Kumar JV, Shetty GG
doaj   +1 more source

Fibrinolysis and COVID‐19: A plasmin paradox

Journal of Thrombosis and Haemostasis, 2020
The COVID‐19 pandemic has provided many challenges in the field of thrombosis and hemostasis. Among these is a novel form of coagulopathy that includes exceptionally high levels of D‐dimer.
R. Medcalf, C. Keragala, P. Myles
semanticscholar   +1 more source

Fibrinolysis and Inflammation in Venous Thrombus Resolution

Frontiers in Immunology, 2019
Clinical observations and accumulating laboratory evidence support a complex interplay between coagulation, inflammation, innate immunity and fibrinolysis in venous thromboembolism (VTE).
Subhradip Mukhopadhyay, Tierra A. Johnson, Nadire Duru, Marguerite S Buzza, Nisha R. Pawar, R. Sarkar, T. Antalis   +6 more
semanticscholar   +1 more source

Mechanical Stability and Fibrinolytic Resistance of Clots Containing Fibrin, DNA, and Histones [PDF]

, 2013
Neutrophil extracellular traps are networks of DNA and associated proteins produced by nucleosome release from activated neutrophils in response to infection stimuli and have recently been identified as key mediators between innate immunity, inflammation,
Szabó, László, Szab , L., Hoell, Armin, Kolev, Krasimir, Sótonyi, Péter, Longstaff, C., Longstaff C, Krumrey, M., Komorowicz, E., Longstaff, Colin, Varjú, Imre, Kolev, K., Varga, Z., Kolev, Kraszimir Nikolaev, Komorowicz, Erzsébet, Krumrey, Michael, Hoell A, S tonyi, P., Krumrey M, Varju, I., Hoell, A., Bóta, Attila, Varga, Zoltán, B ta, A.   +23 more
core   +1 more source

Fibrin Breakdown Assay

Bio-Protocol, 2020
Fibrinolysis is an integral part of the matrix remodeling process that contributes to tissue repair. Fibrin clots are broken down during fibrinolysis in a controlled process.
Jiayue Ling, Connor Blair, George Baillie   +2 more
doaj   +1 more source

Microparticles and Fibrinolysis [PDF]

Seminars in Thrombosis and Hemostasis, 2016
Microparticles (MPs) are submicronic vesicles which are formed by budding of the cellular membrane of virtually any cell type in response to cell activation or apoptosis. Both circulating MPs and MPs generated within tissues harbor molecules with a large repertoire of biological activities and transfer material to target cells.
Vallier, Loris, Cointe, Sylvie, Lacroix, Romaric, Bonifay, Amandine, Judicone, Coralie, Dignat-George, Francoise, Kwaan, Hau C   +6 more
openaire   +2 more sources

Fibrinolysis and Thrombolysis [PDF]

, 2014
This book familiarizes the reader with some recent trends in the theory and practice of thrombolysis. It covers the field of fibrinolysis from the standpoint of basic scientists and clinicians and delivers the state-of-the-art information on the ...

core   +1 more source

Bleeding Disorders in Primary Fibrinolysis

, 2021
Fibrinolysis is a complex enzymatic process aimed at dissolving blood clots to prevent vascular occlusions. The fibrinolytic system is composed of a number of cofactors that, by regulating fibrin degradation, maintain the hemostatic balance.
Marco Zaffanello, Massimo Franchini, Pier Mannuccio Mannucci   +2 more
core   +1 more source

Fibrin Clot Formation and Lysis in Plasma

Methods and Protocols, 2020
Disturbance in the balance between fibrin formation and fibrinolysis can lead to either bleeding or thrombosis; however, our current routine coagulation assays are not sensitive to altered fibrinolysis.
Julie Brogaard Larsen, Anne-Mette Hvas
doaj   +1 more source