Results 11 to 20 of about 47,940 (267)

Blood clot contraction differentially modulates internal and external fibrinolysis

Journal of Thrombosis and Haemostasis, 2019
Essentials Clot contraction influences the rate of fibrinolysis in vitro. Internal fibrinolysis is enhanced ∼2‐fold in contracted vs. uncontracted blood clots. External fibrinolysis is ∼4‐fold slower in contracted vs.
Valerie Tutwiler, Alina D Peshkova, Giang Lê Minh   +2 more
exaly   +3 more sources

Thrombin Activatable Fibrinolysis Inhibitor (TAFI): An Updated Narrative Review

International Journal of Molecular Sciences, 2021
Thrombin activatable fibrinolysis inhibitor (TAFI), a proenzyme, is converted to a potent attenuator of the fibrinolytic system upon activation by thrombin, plasmin, or the thrombin/thrombomodulin complex.
Machteld Sillen, Paul J Declerck, Declerck Paul J   +2 more
exaly   +2 more sources

Fibrinolysis: an illustrated review

Research and Practice in Thrombosis and Haemostasis, 2023
In response to vessel injury (or other pathological conditions), the hemostatic process is activated, resulting in a fibrous, cellular-rich structure commonly referred to as a blood clot.
Rebecca A Risman, Brittany E Bannish, Nathan E Hudson   +2 more
exaly   +2 more sources

FIBRINOLYSIS: MODERN VIEW, PATHOLOGY, DIAGNOSTICS

Байкальский медицинский журнал
Relevance. Fibrinolysis is an important and integral part of the hemostasis system. Acting in parallel and together, the blood coagulation and fibrinolysis systems protect the body from excessive thrombus formation and vascular occlusion, on the one hand,
Lyudmila O. Gutsol, Irina E. Egorova, Igor Zh. Seminsky, Evgenia V. Guzovskaiia, Svetlana N. Serebrennikova, Lyudmila A. Dmitrieva   +5 more
doaj   +2 more sources

Assessment of Fibrinolysis in Sepsis Patients with Urokinase Modified Thromboelastography. [PDF]

PLoS ONE, 2015
IntroductionImpairment of fibrinolysis during sepsis is associated with worse outcome. Early identification of this condition could be of interest. The aim of this study was to evaluate whether a modified point-of-care viscoelastic hemostatic assay can ...
Mauro Panigada, Lucia Zacchetti, Camilla L'Acqua, Massimo Cressoni, Massimo Boscolo Anzoletti, Rossella Bader, Alessandro Protti, Dario Consonni, Armando D'Angelo, Luciano Gattinoni   +9 more
doaj   +2 more sources

Abnormal plasma clot formation and fibrinolysis reveal bleeding tendency in patients with partial factor XI deficiency

Blood Advances, 2018
: Individuals with factor XI (FXI) deficiency have a variable bleeding risk that cannot be predicted from plasma FXI antigen or activity. This limitation can result in under- or overtreatment of patients and risk of bleeding or thrombosis.
Gillian N. Gidley, Lori A. Holle, John Burthem, Paula H.B. Bolton-Maggs, Feng-Chang Lin, Alisa S. Wolberg   +5 more
doaj   +2 more sources

Fibrinolysis and the control of blood coagulation

Blood Reviews, 2015
John Chapin, Katherine A Hajjar
exaly   +2 more sources

Beyond fibrinolysis: The confounding role of Lp(a) in thrombosis.

Atherosclerosis, 2022
Elevated plasma concentrations of lipoprotein(a) (Lp(a)) are a causal risk factor for the development of atherothrombotic disorders including coronary heart disease.
M. Boffa
semanticscholar   +1 more source

Fibrinolysis Shutdown in COVID-19: Clinical Manifestations, Molecular Mechanisms, and Therapeutic Implications

Journal of the American College of Surgeons, 2021
The COVID-19 pandemic has introduced a global public health threat unparalleled in our history. The most severe cases are marked by ARDS attributed to microvascular thrombosis.
J. Meizoso, H. Moore, E. Moore
semanticscholar   +1 more source

Fibrinolysis vs. primary percutaneous coronary intervention for ST‐segment elevation myocardial infarction cardiogenic shock

ESC Heart Failure, 2021
Aims There are limited contemporary data on the use of initial fibrinolysis in ST‐segment elevation myocardial infarction cardiogenic shock (STEMI‐CS). This study sought to compare the outcomes of STEMI‐CS receiving initial fibrinolysis vs.
Saraschandra Vallabhajosyula, Dhiran Verghese, Malcolm R. Bell, Dennis H. Murphree, Wisit Cheungpasitporn, P. Elliott Miller, Shannon M. Dunlay, Abhiram Prasad, Gurpreet S. Sandhu, Rajiv Gulati, Mandeep Singh, Amir Lerman, Bernard J. Gersh, David R. Holmes Jr, Gregory W. Barsness   +14 more
doaj   +1 more source