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Plasmin–Plasminogen System and Milk Physicochemical Traits in Intensively Reared Chios and Frizarta Ewes: Effects of Lactation Stage, Age, and Somatic Cell Count [PDF]

open access: yesAnimals
The objective of the present study is to evaluate the effects of lactation stage, age, somatic cell count (SCC), and daily milk yield on plasmin–plasminogen (PL–PG) system activity and physicochemical milk traits in intensively reared Chios and Frizarta ...
Aphrodite I. Kalogianni   +4 more
doaj   +2 more sources

A multifunctional enolase mediates cytoadhesion and interaction with host plasminogen and fibronectin in Mycoplasma hyorhinis

open access: yesVeterinary Research, 2022
Mycoplasma hyorhinis may cause systemic inflammation of pigs, typically polyserositis and arthritis, and is also associated with several types of human cancer. However, the pathogenesis of M.
Jia Wang   +12 more
doaj   +1 more source

C-Terminal Lysine Residue of Pneumococcal Triosephosphate Isomerase Contributes to Its Binding to Host Plasminogen

open access: yesMicroorganisms, 2023
The main causative agent of pneumonia, Streptococcus pneumoniae, is also responsible for invasive diseases. S. pneumoniae recruits human plasminogen for the invasion and colonization of host tissues. We previously discovered that S.
Satoru Hirayama   +4 more
doaj   +1 more source

Surface Protein Dispersin of Enteroaggregative Escherichia coli Binds Plasminogen That Is Converted Into Active Plasmin

open access: yesFrontiers in Microbiology, 2020
Dispersin is a 10.2 kDa-immunogenic protein secreted by enteroaggregative Escherichia coli (EAEC). In the prototypical EAEC strain 042, dispersin is non-covalently bound to the outer membrane, assisting dispersion across the intestinal mucosa by ...
Claudia T. P. Moraes   +11 more
doaj   +1 more source

MHJ_0125 is an M42 glutamyl aminopeptidase that moonlights as a multifunctional adhesin on the surface of Mycoplasma hyopneumoniae [PDF]

open access: yesOpen Biology, 2013
Bacterial aminopeptidases play important roles in pathogenesis by providing a source of amino acids from exogenous proteins, destroying host immunological effector peptides and executing posttranslational modification of bacterial and host proteins.
Mark W. Robinson   +12 more
doaj   +1 more source

Fibrinolysis regulation by platelets retaining plasminogen and tissue-type plasminogen activator on their surface [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2019
Platelets play a key role in hemostasis as cofactors of thrombin generation, fibrin polymerization centers­, and initiators of clot retraction, while their ability to modulate clot dissolution remains less understood.
T. Grinenko   +4 more
doaj   +1 more source

All tangled up: interactions of the fibrinolytic and innate immune systems

open access: yesFrontiers in Medicine, 2023
The hemostatic and innate immune system are intertwined processes. Inflammation within the vasculature promotes thrombus development, whilst fibrin forms part of the innate immune response to trap invading pathogens.
Claire S. Whyte
doaj   +1 more source

PRODUCTION AND CHARACTERISTICS OF ANTIBODIES AGAINST K1-3 FRAGMENT OF HUMAN PLASMINOGEN [PDF]

open access: yesBiotechnologia Acta, 2013
Components of plasminogen/plasmin system play crucial role in fibrinolytic rocesses. They are also involved in regulation of cell activity in normalcy and various pathological conditions.
A. A. Tykhomyrov   +4 more
doaj   +1 more source

Essential role of DNA-PKcs and plasminogen for the development of doxorubicin-induced glomerular injury in mice

open access: yesDisease Models & Mechanisms, 2021
Susceptibility to doxorubicin-induced nephropathy (DIN), a toxic model for the induction of proteinuria in mice, is related to the single-nucleotide polymorphism (SNP) C6418T of the Prkdc gene encoding for the DNA-repair enzyme DNA-PKcs.
Bernhard N. Bohnert   +17 more
doaj   +1 more source

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