Results 31 to 40 of about 136,149 (288)

Plasminogen–receptor KT: plasminogen activation and beyond [PDF]

Journal of Thrombosis and Haemostasis, 2017
The cell surface orchestrates plasminogen activation through the concomitant binding of plasminogen and plasminogen activators to specific receptors. In this issue, Miles and colleagues describe their detailed phenotypic characterization of mice deficient in Plg-RKT, a key plasminogen receptor expressed in numerous tissues, but highly expressed by ...
M J, Flick, T H, Bugge
openaire   +2 more sources

The Complement Binding and Inhibitory Protein CbiA of Borrelia miyamotoi Degrades Extracellular Matrix Components by Interacting with Plasmin(ogen)

Frontiers in Cellular and Infection Microbiology, 2018
The emerging relapsing fever spirochete Borrelia (B.) miyamotoi is transmitted by ixodid ticks and causes the so-called hard tick-borne relapsing fever or B. miyamotoi disease (BMD).
Ngoc T. T. Nguyen, Florian Röttgerding, Gayatri Devraj, Yi-Pin Lin, Arno Koenigs, Arno Koenigs, Peter Kraiczy   +6 more
doaj   +1 more source

Featured Species-Specific Loops Are Found in the Crystal Structure of Mhp Eno, a Cell Surface Adhesin From Mycoplasma hyopneumoniae

Frontiers in Cellular and Infection Microbiology, 2019
Enolase is an evolutionarily conserved enzyme involved in the processes of glycolysis and gluconeogenesis. Mycoplasma hyopneumoniae belongs to Mycoplasma, whose species are wall-less and among the smallest self-replicating bacteria, and is an important ...
Rong Chen, Yanfei Yu, Zhixin Feng, Rong Gan, Xing Xie, Zhenzhen Zhang, Qingyun Xie, Weiwu Wang, Tingting Ran, Wei Zhang, Qiyan Xiong, Qiyan Xiong, Guoqing Shao, Guoqing Shao   +13 more
doaj   +1 more source

Monitoring of fibrinolytic system activity with plasminogen, D-dimers and FDP in primary total knee arthroplasty (TKA) after topical, intravenous or combined administration of tranexamic acid

Biomedical Papers, 2020
Aim: We assessed various ways of tranexamic acid (TXA) administration on the fibrinolytic system. Blood loss, transfusions, drainage and haematoma were secondary outcomes.
Jiri Lostak, Jiri Gallo, Ludek Slavik, Jana Zapletalova, Lubos Balaz   +4 more
doaj   +1 more source

Urokinase-Type Plasminogen Activator Promotes Paracellular Transmigration of Neutrophils Via Mac-1, But Independently of Urokinase-Type Plasminogen Activator Receptor [PDF]

, 2011
Background: Urokinase-type plasminogen activator (uPA) has recently been implicated in the pathogenesis of ischemia-reperfusion (I/R) injury. The underlying mechanisms remain largely unclear.
Paul J. Declerck, Rehberg, Markus, Daniel Puhr-Westerheide, Lerchenberger, Max, Uhl, Bernd, Kanse, Sandip, Johanna Liebl, Reichel, Christoph A., Bernd Uhl, Markus Rehberg, Zahler, Stefan, Lorenzl, Stefan, Elisabeth Deindl, Khandoga, Andrej, Declerck, Paul J., Stefan Zahler, Schmalix, Wolfgang, Fritz Krombach, Liebl, Johanna, Christoph A. Reichel, Krombach, Fritz, Max Lerchenberger, Andrej Khandoga, Stefan Lorenzl, Deindl, Elisabeth, Wolfgang Schmalix, Puhr-Westerheide, Daniel, Sandip Kanse   +27 more
core   +1 more source

Cyclo19,31[D-Cys19]-uPA19-31 is a potent competitive antagonist of the interaction of urokinase-type plasminogen activator with its receptor (CD87) [PDF]

, 2001
Urokinase-type plasminogen activator (uPA) represents a central molecule in pericellular proteolysis and is implicated in a variety of physiological and pathophysiological processes such as tissue remodelling, wound healing, tumor invasion, and ...
Kellermann, Josef, Wilhelm, Olaf G., Riemer, Christoph, Bürgle, Markus, Schroeck, Florian, Schmitt, Manfred, Kessler, Horst, Degitz, Klaus, Arroyo de Prada, Nuria, Schmiedeberg, Niko, Magdolen, Viktor   +10 more
core   +1 more source

Development and application of global assays of hyper‐ and hypofibrinolysis

Research and Practice in Thrombosis and Haemostasis, 2020
Numerous methods for evaluation of global fibrinolytic activity in whole blood or plasma have been proposed, with the majority based on tissue‐type plasminogen activator (t‐PA) addition to initiate fibrinolysis. We propose that such an approach is useful
Anton Ilich, Denis F. Noubouossie, Michael Henderson, Patrick Ellsworth, Kathleen F. Molitor, Elena Campello, Shannon Meeks, Amy Dunn, Myung S. Park, Rafal Pawlinski, Paolo Simioni, Amy Shapiro, Nigel S. Key   +12 more
doaj   +1 more source

Identification of the binding site for plasminogen kringle 5 in the α-chain of fibrin(ogen) D-fragment [PDF]

The Ukrainian Biochemical Journal, 2020
The interaction of the fifth kringle of Glu-plasminogen with fibrin triggers activation and initiation of fibrinolysis, yet the site on fibrin that binds kringle 5 remains unknown.
L. G. Kapustianenko, T. V. Grinenko, A. V. Rebriev, O. I. Yusova, A. A. Tykhomyrov   +4 more
doaj   +1 more source

Gelsolin induces colorectal tumor cell invasion via modulation of the urokinase-type plasminogen activator cascade [PDF]

, 2012
Gelsolin is a cytoskeletal protein which participates in actin filament dynamics and promotes cell motility and plasticity. Although initially regarded as a tumor suppressor, gelsolin expression in certain tumors correlates with poor prognosis and ...
Prem Kumar, Sutherland K Maciver, Manuel Salto-tellez, Celestial T. Yap (142210), Tochhawng, L., Zhuo, J., Celestial T Yap, Maciver, S.K., Koh, Shiuan, K. Maciver, Salto-Tellez Manuel, Manikandan Jayapal (64624), Tan, Ee Hong, Hooi, S., Jayapal, Manikandan, Maciver, Sutherland K., Yaw Chyn Lim (142208), Zhuo Jingli, Lalchhandami Tochhawng (142188), Jingli Zhuo, Ee Hong Tan (142182), Ee Hong Tan, Alan Prem Kumar (142201), Tay Hwee Kee, Lim, Yaw Chyn, Tay, H., Kumar, A.P., Tochhawng, Lalchhandami, Alan Prem Kumar, Maciver, Sutherland K, Ami Tochhawng, Koh, S., Salto-Tellez, M., Hwee Kee Tay (64625), Tay, H.K., Maciver, S., Benedict Yan (142185), Yap Celestial T., Kumar, Alan Prem, Shiuan Koh (142191), Lalchhandami Tochhawng, Lim, Y., Shing Chuan Hooi (50996), Jayapal Manikandan, Goh, Yaw Chong, Shiuan Koh, Tan, E.H., Yap, C., Yap, Celestial T, Yap, Celestial T., Tochhawng Lalchhandami, Tan, E., Lim, Y.C., Hooi, Shing Chuan, An Jayapal, Yan, B., Hwee Kee Tay, Hooi, S.C., Kumar Alan Prem, Sutherland K. Maciver (142194), Tan Ee Hong, Celestial T. Yap, Goh, Y., Manikandan Jayapal, Maciver Sutherland K., Goh Yaw Chong, Jingli Zhuo (142178), Zhuo, Jingli, Yap, C.T., Benedict Yan, Lim Yaw Chyn, Yan, Benedict, Jayapal, M., Yaw Chyn Lim, Goh, Y.C., Salto-Tellez, Manuel, Yaw Chong Goh, Yaw Chong Goh (142205), Koh Shiuan, Yan Benedict, Hooi Shing Chuan, Manuel Salto-Tellez (142198), Tay, Hwee Kee, Shing Chuan Hooi   +83 more
core   +1 more source

Moonlighting Proteins at the Candidal Cell Surface

Microorganisms, 2020
The cell wall in Candida albicans is not only a tight protective envelope but also a point of contact with the human host that provides a dynamic response to the constantly changing environment in infection niches.
Dorota Satala, Justyna Karkowska-Kuleta, Aleksandra Zelazna, Maria Rapala-Kozik, Andrzej Kozik   +4 more
doaj   +1 more source