Pharmacological evaluation of Adenostemma lavenia acetone extract in Swiss Albino mice: Analgesic, anti-inflammatory, and thrombolytic insights from in vivo, in vitro, density functional theory, and molecular docking studies. [PDF]
Adenostemma lavenia, a traditionally used medicinal plant, has been employed to manage pain, inflammation, and circulatory issues. This study investigates the analgesic, anti‐inflammatory, and thrombolytic potentials of the acetone extract of A. lavenia leaves (AEAL) using in vivo, in vitro, and in silico methods.
Moon NJ +10 more
europepmc +2 more sources
Streptokinase is an enzyme that can break down the blood clots in some cases of myocardial infarction (heart attack), pulmonary embolism, and arterial thromboembolism.
Armi M. Chaudhari +5 more
doaj +1 more source
PLASMINOGEN ACTIVATION BY LOW MOLECULAR WEIGHT STREPTOKINASE AND FIBRIN EFFECT [PDF]
The purpose is to study the plasminogen-activating activity of 36 kDa-streptokinase fragment, influences of desAB-fibrin on this process and low molecular weight streptokinase on plasmin catalytic properties as well. The 36 kDa-fragment lacking the 63
E. I. Yusova
doaj +1 more source
The Comparison between the Outcomes of Streptokinase and Primary Percutaneous Coronary Intervention in Acute Myocardial Infarction [PDF]
Background: To compare between the outcomes of streptokinase and primary PCI in acute myocardial infarction. The inappropriate treatment, misdiagnosis, contraindications of procedures can result in complications of procedures and increased mortality of ...
Zarnab Tariq, Majid Kaleem
doaj +1 more source
Early administration of thrombolytic agents is standard for patients presenting with acute myocardial infarction (MI). Also, prolonged QT intervals indicate a higher risk for sudden death in patients with MI.
Reza Ghasemi +3 more
doaj +1 more source
Early administration of thrombolytic agents is the standard treatment and crucial for the outcome for patients presenting with acute myocardial infarction (MI). This study was conducted to evaluate the door to needle time of streptokinase administration
Reza Ghasemi +3 more
doaj +1 more source
Emphasizing the Pharmacological Potentials of the Methanolic Extract of Wedelia montana: A Prominent Source of Veterinary Medicine. [PDF]
The research focused on Wedelia montana (Blume) Boerl because of its numerous medicinal applications. W. montana belongs to the Asteraceae family. This investigation is intended to analyze the phytochemical content of the methanol extract of W. montana (MEWM) and evaluate its biological features by utilizing in vitro and in vivo models.
Mesu MH +9 more
europepmc +2 more sources
Context Parapneumonic effusion and empyema are commonly encountered by the pulmonologist. The decision regarding management is still challenging.
Mervat A Abou Ismail +3 more
doaj +1 more source
Contribution of Streptokinase-Domains from Groups G and A (SK2a) Streptococci in Amidolytic /Proteolytic Activities and Fibrin-Dependent Plasminogen Activation: A Domain-Exchange Study [PDF]
Background: SK, a heterogeneous PA protein from groups A, C, and G streptococci (GAS, GCS, GGS, respectively) contains three structural domains (SKα, SKβ, and SK).
Maryam Rafipour +4 more
doaj +1 more source
Antibodies to streptokinase [PDF]
Once is enough Thrombolysis is established treatment in the early management of myocardial infarction, and it reduces 35 day mortality by about a quarter.1 The GUSTO study has suggested some advantage of alteplase (rt-PA) over streptokinase with regard to early patency of the occluded coronary artery.2 In particular, GUSTO has suggested that patients ...
openaire +2 more sources

