Results 1 to 10 of about 21,136 (195)

CRISPR-Cas9 Mediated Knockout of SagD Gene for Overexpression of Streptokinase in Streptococcus equisimilis

open access: yesMicroorganisms, 2022
Streptokinase is an enzyme that can break down the blood clots in some cases of myocardial infarction (heart attack), pulmonary embolism, and arterial thromboembolism.
Armi M. Chaudhari   +5 more
doaj   +1 more source

PLASMINOGEN ACTIVATION BY LOW MOLECULAR WEIGHT STREPTOKINASE AND FIBRIN EFFECT [PDF]

open access: yesBiotechnologia Acta, 2014
The purpose is to study the plasminogen-activating activity of 36 kDa-streptokinase fragment, influences of desAB-fibrin on this process and low molecular weight streptokinase on plasmin catalytic properties as well. The 36 kDa-fragment lacking the 63
E. I. Yusova
doaj   +1 more source

The Effect of the Door to Needle Time of Streptokinase Administration on the QTc Interval and the Incidence of Life-Threatening Arrhythmia in Patients With Anterior Myocardial Infarction

open access: yesActa Medica Iranica, 2022
Early administration of thrombolytic agents is standard for patients presenting with acute myocardial infarction (MI). Also, prolonged QT intervals indicate a higher risk for sudden death in patients with MI.
Reza Ghasemi   +3 more
doaj   +1 more source

The Effect of the Door to Needle Time of Streptokinase Administration on the Left Ventricular Function and Thrombolysis in Myocardial Infarction (TIMI) Flow Grade in Patients With Anterior Myocardial Infarction:A Single-Center, Prospective Follow-up Study

open access: yesActa Medica Iranica, 2022
Early administration of thrombolytic agents is the standard treatment and crucial for the outcome for patients presenting with acute myocardial infarction (MI). This study was conducted to evaluate the door to needle time of streptokinase administration
Reza Ghasemi   +3 more
doaj   +1 more source

Intrapleural streptokinase with pigtail catheter drainage versus medical thoracoscopy in complicated parapneumonic effusion

open access: yesEgyptian Journal of Chest Disease and Tuberculosis, 2023
Context Parapneumonic effusion and empyema are commonly encountered by the pulmonologist. The decision regarding management is still challenging.
Mervat A Abou Ismail   +3 more
doaj   +1 more source

Contribution of Streptokinase-Domains from Groups G and A (SK2a) Streptococci in Amidolytic /Proteolytic Activities and Fibrin-Dependent Plasminogen Activation: A Domain-Exchange Study [PDF]

open access: yesIranian Biomedical Journal, 2020
Background: SK, a heterogeneous PA protein from groups A, C, and G streptococci (GAS, GCS, GGS, respectively) contains three structural domains (SKα, SKβ, and SK).
Maryam Rafipour   +4 more
doaj   +1 more source

The Comparison between the Outcomes of Streptokinase and Primary Percutaneous Coronary Intervention in Acute Myocardial Infarction

open access: yesThe International Journal of Frontier Sciences, 2017
Background: To compare between the outcomes of streptokinase and primary PCI in acute myocardial infarction. The inappropriate treatment, misdiagnosis, contraindications of procedures can result in complications of procedures and increased mortality of ...
Zarnab Tariq, Majid Kaleem
doaj   +1 more source

Evaluation of clinical efficacy of streptokinase by comparison with the thrombolytic agent on animal model [PDF]

open access: yesBrazilian Journal of Biology
Cardiovascular disorders, including acute myocardial infarction (AMI), often lead to blood clot formation, impacting blood circulation. Streptokinase, a cost-effective and widely available thrombolytic agent, is crucial in treating thrombosis. This study
S. Yousaf   +6 more
doaj   +1 more source

Cloning and expression of truncated and intact streptokinase molecules in E.coli and evaluation of their biological activities [PDF]

open access: yesمجله بیوتکنولوژی کشاورزی, 2010
Streptokinase is the most utilized drug for thrombolytic therapy. However, due to its nonhuman origin and nonspecific activity in the absence of fibrin, its application may encounter side effects such as allergic reactions and hemorrhage respectively. It
Reza Arabi   +7 more
doaj   +1 more source

Purification and characterization of recombinant Streptokinase expressed in E.coli from Streptococcus equisimilis with N-terminal methionine

open access: yesJurnal Teknologi Laboratorium, 2019
Streptokinase is a extracellular enzyme which is extracted from strains of beta Hemolytic streptococcus. The enzyme is a non-protease plasminogen activator that activates plasminogen to plasmin and degrades fibrin clot through its specific lysine binding
Pavan Kumar Vadla   +2 more
doaj   +1 more source

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