Emphasizing the Pharmacological Potentials of the Methanolic Extract of Wedelia montana: A Prominent Source of Veterinary Medicine. [PDF]
The research focused on Wedelia montana (Blume) Boerl because of its numerous medicinal applications. W. montana belongs to the Asteraceae family. This investigation is intended to analyze the phytochemical content of the methanol extract of W. montana (MEWM) and evaluate its biological features by utilizing in vitro and in vivo models.
Mesu MH +9 more
europepmc +2 more sources
Influence of microrays on the fibrinolytic activities of streptokinase and streptodornase [PDF]
The results of our study may briefly be summarized as follows: 1) The irradiation with microrays (20∼30 watts) similar as 2,000 R and 5,000 R Gamma radiation did not substantially affect the activity of fibrinolysin (SK+SD).
Hajdukovic, Srdjan, Szirmai, Endre
core +1 more source
Rationalism and Empiricism in Modern Medicine [PDF]
The roots of rationalism and empiricism in the Hippocratic tradition are explored. The triumph of the rationalists in the founding of modern medicine is emphasized. The development of clinical epidemiology and the evidence-based medicine over the last 30
Newton, Warren
core +2 more sources
Dose de-escalation of intrapleural tissue plasminogen activator therapy for pleural infection. The alteplase dose assessment for Pleural infection Therapy project [PDF]
Rationale: Intrapleural therapy with a combination of tissue plasminogen activator (tPA) 10 mg and DNase 5 mg administered twice daily has been shown in randomized and open-label studies to successfully manage over 90% of patients with pleural infection ...
Bintcliffe, Oliver +10 more
core +1 more source
Spectrophotometric analysis of thrombolytic activity: SATA assay [PDF]
Introduction: Measurement of thrombolytic activity i.e. clot lysis is crucial for research and development of novel thrombolytics. It is also a key factor in assessment of the effectiveness of conventionally used thrombolytic agents in the clinic, which ...
Entekhabi, Nazila +5 more
core +2 more sources
Assessing the effectiveness of primary angioplasty compared with thrombolysis and its relationship to time delay: a Bayesian evidence synthesis [PDF]
Background: Meta-analyses of trials have shown greater benefits from angioplasty than thrombolysis after an acute myocardial infarction, but the time delay in initiating angioplasty needs to be considered.
Abrams, Keith R. +6 more
core +4 more sources
Is primary angioplasty cost effective in the UK? Results of a comprehensive decision analysis [PDF]
Objective: To assess the cost effectiveness of primary angioplasty, compared with medical management with thrombolytic drugs, to achieve reperfusion after acute myocardial infarction ( AMI) from the perspective of the UK NHS.
Abrams, Keith +6 more
core +2 more sources
Molecular Characterization of the Group A Streptococcus Virulence-Regulatory System FasBCAX. [PDF]
The Fas system of the group A Streptococcus is comprised of three proteins (FasBCA) and a small regulatory RNA (FasX), and it represses adhesin production while also promoting the production of the spreading factor streptokinase. Here, we analyze the Fas proteins to assess how they positively regulate FasX production.
Baral S +9 more
europepmc +2 more sources
High-dose streptokinase in the treatment of acute massive pulmonary embolism complicated with cardiogenic shock, respiratory arrest and ventricular fibrillation [PDF]
Background. Despite advances in prophylaxis, diagnostic modalities, and therapeutic options, pulmonary embolism remains a commonly undiagnosed entity with lethal outcome. Clinically, pulmonary embolism ranges from massive thromboembolism with cardiogenic
Lasica Ratko +4 more
doaj +1 more source
Impact of thrombolytic therapy on the incidence of complex ventricular arrhythmias in the late hospital phase of the acute myocardial infarction: Relation with the long-lasting left ventricle remodeli [PDF]
Background. The impact of thrombolytic therapy on the incidence of complex ventricular arrhythmias is not yet clarified. The aim of this study was to investigate the impact of thrombolytic therapy on the incidence of complex ventricular arrhythmias, as ...
Otašević Petar M. +6 more
doaj +1 more source

