Results 11 to 20 of about 13,759 (198)

Evaluation of In vivo Bioactivity of a Mutated Streptokinase [PDF]

Novelty in Biomedicine, 2017
 Background: Immunogenicity of Streptokinase, as a thrombolytic drug, has limited its clinical use. Elimination of the amino acid residues that are responsible for immunogenicity while don’t affect the bioactivity of streptokinase is worthy. Recently, we
Marzieh Sameni, Mazaher Gholipourmalekabadi, Mojgan Bandehpour, Mehrdad Hashemi, Farzin Sahebjam, V Tohidi, Bahram Kazemi   +6 more
doaj   +2 more sources

Fibrinolytic Activity of Recombinant Mutant Streptokinase [PDF]

Novelty in Biomedicine, 2015
Background: Streptokinase is a bacterial protein produced by different beta hemolytic streptococci and widely used in thrombolytic treatment. The main disadvantage of using streptokinase is antibody formation which causes allergic reaction to neutralize ...
Mahboobeh Mobarrez, Mojgan Bandehpour, Massoud Salehmoghadam, Bahram Kazemi   +3 more
doaj   +2 more sources

SLE Presenting With Unilateral Loculated Pleural Effusion in a Young Hypertensive Female: A Rare Case Report and Literature Review. [PDF]

Clin Case Rep
ABSTRACT SLE can rarely present with unilateral pleural effusion or hypertension. A 28‐year‐old woman with loculated exudative pleural effusion was diagnosed with SLE and lupus nephritis fulfilling EULAR/ACR criteria, treated with pigtail drainage, corticosteroids, and hydroxychloroquine, with good recovery.
Tripathi A, Sah U, Shah S, Singh S, Nishad SR.   +4 more
europepmc   +2 more sources

Pharmacological evaluation of Adenostemma lavenia acetone extract in Swiss Albino mice: Analgesic, anti-inflammatory, and thrombolytic insights from in vivo, in vitro, density functional theory, and molecular docking studies. [PDF]

Animal Model Exp Med
Adenostemma lavenia, a traditionally used medicinal plant, has been employed to manage pain, inflammation, and circulatory issues. This study investigates the analgesic, anti‐inflammatory, and thrombolytic potentials of the acetone extract of A. lavenia leaves (AEAL) using in vivo, in vitro, and in silico methods.
Moon NJ, Mohammad M, Mamun MJI, Nova FBA, Eshaque NH, Rasel MH, Islam Z, Hasan MM, Ali ML, Chowdhury MT, Hossen SMM.   +10 more
europepmc   +2 more sources

Do recipients of kidneys from donors treated with streptokinase develop anti-streptokinase antibodies?

Streptokinase is used for preflush for non-heart-beating donors (NHBDs) in our center. The aim of this study was to evaluate whether the use of thrombolytic streptokinase results in the production of anti-streptokinase antibodies in the recipients after ...
Mi H, Gupta A, Soomro NA, Gok MA, Shenton BK, Carter V, Stamp S, Manas DM, Asher JF, Del Rio Martin J, Jaques BC, Talbot D   +11 more
core   +5 more sources

Streptokinase inhibits pulmonary tumor seeding in an animal experimental model

, 1994
One aspect of the metastatic process involves entrapment of tumor cells within the microcirculation of organs in a "fibrin-platelet mesh." We postulate that destruction of this mesh by fibrinolysis might discourage tumor seeding, thereby inhibiting ...
Purushotham, A D; id_orcid, Choy, A, Anand D. Purushotham, George, W D, William D. George, Peter McCulloch, Douglas C. Brown, Brown, D C, McCulloch, P, Alfred Choy   +9 more
core   +6 more sources

Home-Based Management of a Child With Persistent Pulmonary Air Leak Complicated by Pneumonia. [PDF]

Case Rep Pulmonol
Background Pneumothorax is a condition where air leaks into the space between the visceral and parietal pleura. Community acquired pneumonia is a rare cause of pneumothorax in children. Pneumothorax can sometimes develop as a complication of pneumonia when infection erodes the distal airway into the pleural cavity causing air leak.
Shrestha D, Tuladhar SM, Shrestha MK.
europepmc   +2 more sources

High-dose streptokinase in the treatment of acute massive pulmonary embolism complicated with cardiogenic shock, respiratory arrest and ventricular fibrillation [PDF]

Vojnosanitetski Pregled, 2005
Background. Despite advances in prophylaxis, diagnostic modalities, and therapeutic options, pulmonary embolism remains a commonly undiagnosed entity with lethal outcome. Clinically, pulmonary embolism ranges from massive thromboembolism with cardiogenic
Lasica Ratko, Peruničić Jovan, Mrdović Igor B., Stojanović Radan, Vasiljević Zorana   +4 more
doaj   +1 more source

Purification and characterization of recombinant Streptokinase expressed in E.coli from Streptococcus equisimilis with N-terminal methionine

Jurnal Teknologi Laboratorium, 2019
Streptokinase is a extracellular enzyme which is extracted from strains of beta Hemolytic streptococcus. The enzyme is a non-protease plasminogen activator that activates plasminogen to plasmin and degrades fibrin clot through its specific lysine binding
Pavan Kumar Vadla, Murali Tummuru, Dinesh Kumar   +2 more
doaj   +1 more source

Impact of thrombolytic therapy on the incidence of complex ventricular arrhythmias in the late hospital phase of the acute myocardial infarction: Relation with the long-lasting left ventricle remodeli [PDF]

Vojnosanitetski Pregled, 2003
Background. The impact of thrombolytic therapy on the incidence of complex ventricular arrhythmias is not yet clarified. The aim of this study was to investigate the impact of thrombolytic therapy on the incidence of complex ventricular arrhythmias, as ...
Otašević Petar M., Nešković Aleksandar N., Popović Zoran B., Vlahović Alja, Vuković Milan, Borzanović Branislava, Popović Aleksandar D.   +6 more
doaj   +1 more source