Results 21 to 30 of about 4,363 (145)

High-dose streptokinase in the treatment of acute massive pulmonary embolism complicated with cardiogenic shock, respiratory arrest and ventricular fibrillation [PDF]

Vojnosanitetski Pregled, 2005
Background. Despite advances in prophylaxis, diagnostic modalities, and therapeutic options, pulmonary embolism remains a commonly undiagnosed entity with lethal outcome. Clinically, pulmonary embolism ranges from massive thromboembolism with cardiogenic
Lasica Ratko, Peruničić Jovan, Mrdović Igor B., Stojanović Radan, Vasiljević Zorana   +4 more
doaj   +1 more source

Impact of thrombolytic therapy on the incidence of complex ventricular arrhythmias in the late hospital phase of the acute myocardial infarction: Relation with the long-lasting left ventricle remodeli [PDF]

Vojnosanitetski Pregled, 2003
Background. The impact of thrombolytic therapy on the incidence of complex ventricular arrhythmias is not yet clarified. The aim of this study was to investigate the impact of thrombolytic therapy on the incidence of complex ventricular arrhythmias, as ...
Otašević Petar M., Nešković Aleksandar N., Popović Zoran B., Vlahović Alja, Vuković Milan, Borzanović Branislava, Popović Aleksandar D.   +6 more
doaj   +1 more source

Streptokinase-Induced Anaphylaxis

, 1989
Streptokinase is a thrombolytic agent used most commonly for the dissolution of thrombi obstructing coronary arteries during acute myocardial infarction (MI). Anaphylactic reactions induced by streptokinase occur rarely.
George E. Matthews, James E. Tisdale, Kathleen A. Stringer, Matthew Antalek   +3 more
core   +1 more source

Micro and Nanoparticles as Carriers for Streptokinase: A Mini-Review on Efficacy, Side Effects and Pharmacokinetics [PDF]

Nanomedicine Research Journal
Streptokinase is being successfully used as a thrombolytic agent for restoring the blood flow following thromboembolism and myocardial infarction. However, high immunogenicity of the drug has limited its use in clinics.
Amir Amani
doaj   +1 more source

Effect of streptokinase in the prevention of intra-abdominal adhesions in the rat

Acta Cirúrgica Brasileira, 1997
The objective of the present study was to assess the action of streptokinase, a streptococcal derivative with fibrinolytic capacity, in the prevention of intraperitoneal adhesions in rats. Eighty animals were divided into four groups of 20 each; group A (
Benjamin Smaniotto, Maria de Lourdes Pessole Biondo-Simões, Giocondo Villanova Artigas, Antonio de Padua Gomes da Silva, Luiz Martins Collaço, Gustavo Verner Ramasco   +5 more
doaj   +1 more source

Streptokinase inhibits pulmonary tumor seeding in an animal experimental model

, 1994
One aspect of the metastatic process involves entrapment of tumor cells within the microcirculation of organs in a "fibrin-platelet mesh." We postulate that destruction of this mesh by fibrinolysis might discourage tumor seeding, thereby inhibiting ...
Purushotham, A D; id_orcid, Choy, A, Anand D. Purushotham, George, W D, William D. George, Peter McCulloch, Douglas C. Brown, Brown, D C, McCulloch, P, Alfred Choy   +9 more
core   +3 more sources

Anxiolytic and thrombolytic investigation of methanol extract of Piper nigrum L. fruits and Sesamum indicum L. seeds

Journal of Advanced Biotechnology and Experimental Therapeutics, 2020
The study was intended to compare and evaluate the in vitro thrombolytic activity and in vivo anxiolytic activities of methanol extracts of Piper nigrum fruits (MEPNF) and Sesamum indicum seeds (MESIS).
Nazim Uddin Emon, Md Kaiser, Mohammed Faisal Ibna Kabir, Mohammad Jamir Uddin, Mifta Ahmed Jyoti, Saifullah Mansur Tanjil, Abu Nayem Mohammad Rasel, Safaet Alam, Mohammad Nazmul Islam   +8 more
doaj   +1 more source

Cangrelor Dosing, Administration, and Clinical Outcomes for Patients Undergoing Complex and High‐Risk Percutaneous Coronary Interventions

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Cangrelor reduces thrombotic events in patients undergoing percutaneous coronary intervention (PCI), with the advantage of rapid onset and offset. However, premature discontinuation may increase the risk of acute thrombosis for patients undergoing complex/high‐risk PCI (CHIP).
Siyu Ma, Wendy Y. Cheng, Yinong Liang, Josephine Bryar, Gwyneth Wei, Joshua D. Niznik, Christina Yin, Sue Liu‐Yi, Jimmy L. Kerrigan   +8 more
wiley   +1 more source

Current status and future perspectives of platelet function‐guided precision antiplatelet therapy for patients with cerebral infarction

Neuroprotection, EarlyView.
Antiplatelet agents target the cyclooxygenase‐1 (COX‐1)/thromboxane A2 (TXA2) and adenosine diphosphate (ADP)‐P2Y12 (cytochrome P450 2C19 [CYP2C19]‐metabolized) platelet activation pathways, resulting in either drug resistance or over‐inhibition. The individualized therapeutic window balances ischemic risk (triggered by high on‐treatment platelet ...
Guoliang Zhu, Xiaoling Chen, Xinyi Huang, Quandan Tan, Qing Cao, Yali Yang, Yapeng Lin, Jie Yang   +7 more
wiley   +1 more source

Pulmonary Embolism—A Century of Progress

ANZ Journal of Surgery, EarlyView.
Reviews a century of progress in the diagnosis, prevention, and management of pulmonary embolism; from the first successful surgical embolectomy in 1924 to advanced imaging, pharmacological thromboprophylaxis, and treatment. In the 21st century, advances include catheter‐directed thrombolysis or mechanical thrombectomy under decision‐making guidance of
D. A. Watters
wiley   +1 more source