Results 21 to 30 of about 9,616 (163)

A study of empyema thoracis and role of intrapleural streptokinase in its management

open access: yesBMC Infectious Diseases, 2004
Background Clinical spectrum, microbiology and outcome of empyema thoracis are changing. Intrapleural instillation of fibrinolytic agents is being increasingly used for management of empyema thoracis.
Dey AB   +5 more
doaj   +1 more source

Acute myocardial infarction associated with right bundle branch block and changeable trifascicular block: a case report

open access: yesJournal of Acute Disease, 2019
Rationale: Acute myocardial infarction in the presence of right bundle branch block. Patient concerns: A 70-year-old, male heavy smoker presented with angina and hypertension.
Yasser Mohammed Hassanain Elsayed
doaj   +1 more source

Glycemic Status and Effect of Immediate Intensive Statin on Mild Ischemic Stroke: A Subgroup Analysis of the INSPIRES Trial

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
Immediate‐intensive statin improves functional outcomes in non‐diabetic stroke patients: glycemic status modulates intensive statin treatment response. Early intensive statin therapy should be prioritized in stroke patients without diabetes, whereas alternative strategies may be needed for long‐standing T2DM to optimize functional recovery.
Lingling Jiang   +8 more
wiley   +1 more source

Safety and efficacy of streptokinase in multiloculated pleural effusion in pediatric population

open access: yesIndian Journal of Respiratory Care, 2022
Introduction: Management of complicated parapneumonic effusions (CPEs) and empyema is difficult, as no clear guidelines exist. The use of intrapleural fibrinolytics has shown promising results in several studies.
Akhtar Reza   +4 more
doaj   +1 more source

Right Atrial Thrombus in Transit: A Case of Spontaneous Embolisation Captured Across Echocardiography

open access: yesRespirology Case Reports, Volume 14, Issue 4, April 2026.
In this report, we describe a large RA thrombus in transit captured sequentially across multiple imaging modalities. This case highlights how quickly these thrombi can evolve and emphasises the need for individualised decision‐making when standard interventions are limited by clinical context.
Abdullah Al Qaraghuli   +7 more
wiley   +1 more source

Placenta‐derived extracellular vesicles: Signal messengers shuttling across the maternal‐fetal barrier

open access: yesInterdisciplinary Medicine, Volume 4, Issue 2, March 2026.
In normal pregnancy, PEVs help maintain maternal–fetal immune tolerance while enabling controlled immune activation, promote endothelial migration, and support trophoblast invasion and syncytialization, strengthening antimicrobial defense. In pregnancy‐related disorders, dysregulated PEV signaling may drive endothelial dysfunction and hypertension, BBB
Jiale Du   +5 more
wiley   +1 more source

Medical haematology: Repositioning haematology at the centre of medicine

open access: yesBritish Journal of Haematology, Volume 208, Issue 3, Page 845-854, March 2026.
The complementary domains of Medical Haematology and Haemato‐Oncology share a biological framework. The left panel depicts red cells, platelets, coagulation, thrombosis and innate immunity, while the right panel shows lymphoid and myeloid malignancies.
Cheng Hock Toh, Imelda Bates, Sue Pavord
wiley   +1 more source

Fermentation, fractionation and purification of streptokinase by chemical reduction method

open access: yesIranian Journal of Microbiology, 2011
Background and Objectives: Streptokinase is used clinically as an intravenous thrombolytic agent for the treatment of acute myocardial infarction and is commonly prepared from cultures of Streptococcus equisimilis strain H46A.
Z Karimi   +4 more
doaj  

Activity Regulation by Fibrinogen and Fibrin of Streptokinase from Streptococcus Pyogenes. [PDF]

open access: yesPLoS ONE, 2017
Streptokinase is a virulence factor of streptococci and acts as a plasminogen activator to generate the serine protease plasmin which promotes bacterial metastasis.
Sian Huish   +2 more
doaj   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

open access: yesFEBS Open Bio, Volume 16, Issue 2, Page 314-330, February 2026.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul   +3 more
wiley   +1 more source

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