Results 21 to 30 of about 13,759 (198)

Immunoglobulin Attenuates Streptokinase-Mediated Virulence inStreptococcus dysgalactiae Subspeciesequisimilis Necrotizing Fasciitis [PDF]

, 2021
A clinicalStreptococcus dysgalactiae equisimilis strain secreting high levels of streptokinase promoted severe disease in a patient lacking anti-streptokinase antibodies.
Marques Maggio, Ewerton, Andreoni, Federica, Ugolini, Fabio, Keller, Nadia, Hollands, Andrew, Neff, Andrina, Zinkernagel, Annelies S., Schuepbach, Reto A., Nizet, Victor   +8 more
core  

Streptokinase-Induced Anaphylaxis

, 1989
Streptokinase is a thrombolytic agent used most commonly for the dissolution of thrombi obstructing coronary arteries during acute myocardial infarction (MI). Anaphylactic reactions induced by streptokinase occur rarely.
George E. Matthews, James E. Tisdale, Kathleen A. Stringer, Matthew Antalek   +3 more
core   +1 more source

Anxiolytic and thrombolytic investigation of methanol extract of Piper nigrum L. fruits and Sesamum indicum L. seeds

Journal of Advanced Biotechnology and Experimental Therapeutics, 2020
The study was intended to compare and evaluate the in vitro thrombolytic activity and in vivo anxiolytic activities of methanol extracts of Piper nigrum fruits (MEPNF) and Sesamum indicum seeds (MESIS).
Nazim Uddin Emon, Md Kaiser, Mohammed Faisal Ibna Kabir, Mohammad Jamir Uddin, Mifta Ahmed Jyoti, Saifullah Mansur Tanjil, Abu Nayem Mohammad Rasel, Safaet Alam, Mohammad Nazmul Islam   +8 more
doaj   +1 more source

Micro and Nanoparticles as Carriers for Streptokinase: A Mini-Review on Efficacy, Side Effects and Pharmacokinetics [PDF]

Nanomedicine Research Journal
Streptokinase is being successfully used as a thrombolytic agent for restoring the blood flow following thromboembolism and myocardial infarction. However, high immunogenicity of the drug has limited its use in clinics.
Amir Amani
doaj   +1 more source

Why do patients develop reactions to streptokinase?

, 1993
SUMMARY Minor reactions to streptokinase are not uncommon, although the etiology is unknown. It is widely presumed, however, that these, like the more serious immune reactions, are antibody-mediated. We measured specific anti-streptokinase
M LYNCH, R A STOCKLEY, B L PENTECOST, W A LITTLER   +3 more
core   +1 more source

Streptokinase and streptokinase card: questionnaire validation to evaluate knowledge among post‐STEMI patients in a Malaysian Tertiary Hospital

, 2020
Background: Although recombinant tissue plasminogen activator has become the first-line thrombolytic agent, streptokinase remains in use in acute ST-elevation myocardial infarction (STEMI) patients in Malaysian public hospitals.
Mohd Puad, Norfarazila, Wei Chern Ang, Norfarazila Mohd Puad, Ibrahim, Arief, Arief Ibrahim, Abd Karim, Nur Amirah, Nur Amirah Abd Karim, Ang, Wei Chern   +7 more
core   +1 more source

Current status and future perspectives of platelet function‐guided precision antiplatelet therapy for patients with cerebral infarction

Neuroprotection, EarlyView.
Antiplatelet agents target the cyclooxygenase‐1 (COX‐1)/thromboxane A2 (TXA2) and adenosine diphosphate (ADP)‐P2Y12 (cytochrome P450 2C19 [CYP2C19]‐metabolized) platelet activation pathways, resulting in either drug resistance or over‐inhibition. The individualized therapeutic window balances ischemic risk (triggered by high on‐treatment platelet ...
Guoliang Zhu, Xiaoling Chen, Xinyi Huang, Quandan Tan, Qing Cao, Yali Yang, Yapeng Lin, Jie Yang   +7 more
wiley   +1 more source

Effect of streptokinase in the prevention of intra-abdominal adhesions in the rat

Acta Cirúrgica Brasileira, 1997
The objective of the present study was to assess the action of streptokinase, a streptococcal derivative with fibrinolytic capacity, in the prevention of intraperitoneal adhesions in rats. Eighty animals were divided into four groups of 20 each; group A (
Benjamin Smaniotto, Maria de Lourdes Pessole Biondo-Simões, Giocondo Villanova Artigas, Antonio de Padua Gomes da Silva, Luiz Martins Collaço, Gustavo Verner Ramasco   +5 more
doaj   +1 more source

Pulmonary Embolism—A Century of Progress

ANZ Journal of Surgery, EarlyView.
Reviews a century of progress in the diagnosis, prevention, and management of pulmonary embolism; from the first successful surgical embolectomy in 1924 to advanced imaging, pharmacological thromboprophylaxis, and treatment. In the 21st century, advances include catheter‐directed thrombolysis or mechanical thrombectomy under decision‐making guidance of
D. A. Watters
wiley   +1 more source

Cloning and expression of truncated and intact streptokinase molecules in E.coli and evaluation of their biological activities [PDF]

مجله بیوتکنولوژی کشاورزی, 2010
Streptokinase is the most utilized drug for thrombolytic therapy. However, due to its nonhuman origin and nonspecific activity in the absence of fibrin, its application may encounter side effects such as allergic reactions and hemorrhage respectively. It
Reza Arabi, farzin Roohvand, Daryoosh Noroozian, MohMMdreza AghSADEGHI, Arash Memarnajadian, Hossin khan ahmad, Mehdi Sadat, Fatemah Motavalli   +7 more
doaj   +1 more source