Results 1 to 10 of about 12,086 (222)

Recombinant Expression of Thrombolytic Agent Reteplase in Marine Microalga Tetraselmis subcordiformis (Chlorodendrales, Chlorophyta) [PDF]

open access: yesMarine Drugs, 2021
Tetraselmis subcordiformis, a unicellular marine green alga, is used widely in aquaculture as an initial feeding for fish, bivalve mollusks, penaeid shrimp larvae, and rotifers because of its rich content of amino acids and fatty acids.
Chunhui Wu   +3 more
doaj   +2 more sources

Spectrophotometric analysis of thrombolytic activity: SATA assay [PDF]

open access: yesBioImpacts, 2018
Introduction: Measurement of thrombolytic activity is crucial for research and development of novel thrombolytics. It is a key factor in the assessment of the effectiveness of conventionally used thrombolytic therapies in the clinic.
Masumeh Zamanlu   +5 more
doaj   +4 more sources

Thrombolytic Potential of Micromycetes from the Genus Tolypocladium, Obtained from White Sea Soils: Screening of Producers and Exoproteinases Properties [PDF]

open access: yesMicrobiology Research, 2022
Thrombotherapy is an important approach in treatment of various diseases associated with pathologies of the cardiovascular and human hemostasis systems.
N. S. Fokichev   +4 more
doaj   +2 more sources

Research Progress on Functional Vectors for Nattokinase Delivery [PDF]

open access: yesShipin Kexue, 2023
Nattokinase (NK), a serine protease, can be used as a thrombolytic agent. Compared with clinical thrombolytic drugs (urokinase and streptokinase), NK has the advantages of low price, high thrombolytic efficiency, oral administration, and no toxic side ...
XIE Minghao, XU Xianbing, WANG Zhenyu, CHENG Shuzhen, DU Ming
doaj   +1 more source

In vivo antithrombotic potential of protease from Bacillus thuringiensis HSFI-12 [PDF]

open access: yesScripta Medica, 2023
Background/Aim: Cardiovascular diseases (CVDs) are the primary noncommunicable disease at the global level due to abnormal platelet aggregation by fibrin forming clots in blood vessels called thrombus. The search for thrombolytic drugs is largely carried
Dewi Okta Yosiana   +4 more
doaj   +1 more source

Nanotechnology in Stroke: New Trails with Smaller Scales

open access: yesBiomedicines, 2023
Stroke is a leading cause of death, long-term disability, and socioeconomic costs, highlighting the urgent need for effective treatment. During acute phase, intravenous administration of recombinant tissue plasminogen activator (tPA), a thrombolytic ...
Karlo Toljan   +3 more
doaj   +1 more source

Tenecteplase Thrombolysis in Posterior Circulation Stroke

open access: yesFrontiers in Neurology, 2021
One in five ischaemic strokes affects the posterior circulation. Basilar artery occlusion is a type of posterior circulation stroke associated with a high risk of disability and mortality.
Fana Alemseged, Bruce C. V. Campbell
doaj   +1 more source

Histomorphometric analysis of the lung of Swiss mice treated with a fibrinolytic protease

open access: yesAnais da Academia Brasileira de Ciências, 2022
Fibrinolytic enzymes are considered promising alternative in the treatment of cardiovascular diseases by preventing fibrin clots. A protease from Mucor subtilissimus UCP 1262 was obtained by solid state fermentation and purified by ion exchange ...
MARLLYN M. DA SILVA   +10 more
doaj   +1 more source

An in vitro model for experimental evaluation of sonothrombolysis under tissue-mimicking material conditions

open access: yesJournal of Medical Ultrasound, 2023
Background: The mechanical properties of therapeutic ultrasound (US) have attracted scientific interest for thrombolysis enhancement in combination with thrombolytic agents and microbubbles (MBs).
Theocharis Drakos   +2 more
doaj   +1 more source

Thrombolytic therapy delay is independent predictor of mortality in acute pulmonary embolism at emergency service

open access: yesKaohsiung Journal of Medical Sciences, 2016
Acute pulmonary embolism (PE) carries a high risk of morbidity and mortality. Delays in diagnosis or therapy may result in sudden, fatal deterioration; therefore, rapid diagnosis and an appropriate therapeutic approach are needed. We aimed to investigate
İnan Beydilli   +7 more
doaj   +1 more source

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