Tenecteplase or Alteplase: What Is the Thrombolytic Agent of the Future? [PDF]
Curr Treat Options Neurol, 2022 Alteplase has been the thrombolytic of choice for acute ischaemic stroke for more than two decades. A thrombolytic which is easier to administer and with improved or comparable safety and efficacy is desirable.
Mahmood A, Muir KW.
europepmc +3 more sources
Recombinant Expression of Thrombolytic Agent Reteplase in Marine Microalga Tetraselmis subcordiformis (Chlorodendrales, Chlorophyta) [PDF]
Marine Drugs, 2021 Tetraselmis subcordiformis, a unicellular marine green alga, is used widely in aquaculture as an initial feeding for fish, bivalve mollusks, penaeid shrimp larvae, and rotifers because of its rich content of amino acids and fatty acids.
Chunhui Wu +3 more
doaj +2 more sources
Urokinase Plasminogen Activator: A Potential Thrombolytic Agent for Ischaemic Stroke. [PDF]
Cell Mol Neurobiol, 2020 Kadir RRA, Bayraktutan U.
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Barriers to intravenous thrombolysis in acute ischemic stroke: a retrospective case report series from Honduras [PDF]
Frontiers in StrokeBackground and purposeIntravenous (IV) thrombolysis for acute ischemic stroke (AIS) is time-dependent and frequently underused in resource-limited settings.
Jesús Antonio Rodríguez Santos +6 more
doaj +2 more sources
Frontiers in Materials, 2019 Non-invasive removal of thrombosis is a difficult problem in clinical vascular disease. Herein, we reported magnetic hyperthermia combined photothermal therapy for celiac vein thrombosis using Fe3S4 nanoparticles as thrombolytic agents under the ...
Dapeng Fu +8 more
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Research Progress on Functional Vectors for Nattokinase Delivery [PDF]
Shipin Kexue, 2023 Nattokinase (NK), a serine protease, can be used as a thrombolytic agent. Compared with clinical thrombolytic drugs (urokinase and streptokinase), NK has the advantages of low price, high thrombolytic efficiency, oral administration, and no toxic side ...
XIE Minghao, XU Xianbing, WANG Zhenyu, CHENG Shuzhen, DU Ming
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In vivo antithrombotic potential of protease from Bacillus thuringiensis HSFI-12 [PDF]
Scripta Medica, 2023 Background/Aim: Cardiovascular diseases (CVDs) are the primary noncommunicable disease at the global level due to abnormal platelet aggregation by fibrin forming clots in blood vessels called thrombus. The search for thrombolytic drugs is largely carried
Dewi Okta Yosiana +4 more
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Prosthetic Valve Thrombosis: Thrombolytic Agent Selection and Imaging Guidance [PDF]
Clinical and Applied Thrombosis/HemostasisFidel Manuel Caceres-Loriga MD, PhD +1 more
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Nanotechnology in Stroke: New Trails with Smaller Scales
Biomedicines, 2023 Stroke is a leading cause of death, long-term disability, and socioeconomic costs, highlighting the urgent need for effective treatment. During acute phase, intravenous administration of recombinant tissue plasminogen activator (tPA), a thrombolytic ...
Karlo Toljan +3 more
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Microlyse; a thrombolytic agent that targets VWF for clearance of microvascular thrombosis.
Blood, 2021 Thrombotic microangiopathies are hallmarked by attacks of disseminated microvascular thrombosis. In thrombotic thrombocytopenic purpura (TTP), this is caused by a rise in thrombogenic ultra-large von Willebrand factor (VWF) multimers because of ADAMTS13 ...
S. de Maat +18 more
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