Results 41 to 50 of about 21,136 (195)
Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
FEBS Open Bio, Volume 16, Issue 2, Page 314-330, February 2026.We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
Veterinary Record Case Reports, Volume 14, Issue 1, February 2026.Abstract An 8‐year‐old male neutered domestic shorthair cat was presented for the management of severe anaemia and post‐urethral obstruction care. A large intravesicular lesion, which was suspected to be a haematoma, was identified via abdominal ultrasound. This was suspected to be secondary to bleeding in the urinary tract.
Alison Robertson, Laura Cole, Karen Humm
wiley +1 more source
Labeling of the Recombinant Streptokinase Using Iodine-131 as a New Thrombolytic Agent [PDF]
, 2012 Stroke and acute myocardial infarction is a disease with the highest mortality in the world. WHO has estimated in 2008, 30% of deaths from heart disease and more than 80% of this cases have been occurred in developing countries.
Daruwati, I. (I) +3 more
core +3 more sources
Iranian Journal of Allergy, Asthma and Immunology, 2004 The measurement of anti-streptokinase antibodies can distinguish the patients who may benefit from streptokinase and those who should be treated with some other thrombolytic regimen.
Afshin Afshari R. Elizbeth Holme
doaj
Activity Regulation by Fibrinogen and Fibrin of Streptokinase from Streptococcus Pyogenes. [PDF]
PLoS ONE, 2017 Streptokinase is a virulence factor of streptococci and acts as a plasminogen activator to generate the serine protease plasmin which promotes bacterial metastasis.
Sian Huish +2 more
doaj +1 more source
Advances in Pharmacological and Pharmaceutical Sciences, Volume 2026, Issue 1, 2026.Current evidence suggests that regular consumption of food‐functioned fruits and vegetables could reduce the risk of thrombosis. While some indigenous vegetables from Southern Thailand have been reported to exhibit anticoagulant and antiplatelet activities, their fibrinolytic and thrombolytic properties remain unexplored.
Surachai Techaoei +4 more
wiley +1 more source
Fermentation, fractionation and purification of streptokinase by chemical reduction method
Iranian Journal of Microbiology, 2011 Background and Objectives: Streptokinase is used clinically as an intravenous thrombolytic agent for the treatment of acute myocardial infarction and is commonly prepared from cultures of Streptococcus equisimilis strain H46A.
Z Karimi +4 more
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Scientifica, Volume 2026, Issue 1, 2026.Hibiscus macrophyllus Roxb. (Malvaceae) is traditionally used in Southeast Asia for the management of gastrointestinal disorders, pain, and fever; however, scientific evidence supporting the pharmacological potential of its bark remains limited. The present study aimed to evaluate the pharmacological properties of bark extracts of H.
Labuni Chowdhury +8 more
wiley +1 more source
Effects of early intracoronary streptokinase on infarct size estimated from cumulative enzyme release and on enzyme release rate: A randomized trial of 533 patients with acute myocardial infarction [PDF]
, 1986 The effects of early intracoronary streptokinase (SK) on enzymatic infarct size and rate of enzyme release were studied in a randomized multicenter trial.
Bär, F.W.H.M. (Frits) +12 more
core +5 more sources
Evaluation of In vivo Bioactivity of a Mutated Streptokinase
Novelty in Biomedicine, 2017 Background: Immunogenicity of Streptokinase, as a thrombolytic drug, has limited its clinical use. Elimination of the amino acid residues that are responsible for immunogenicity while don’t affect the bioactivity of streptokinase is worthy. Recently, we
Marzieh Sameni +6 more
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