Results 41 to 50 of about 4,363 (145)
A pilot study of streptokinase for acute cerebral infarction
We evaluated intravenous streptokinase in the treatment of cerebral infarction. Following neurological assessment and cerebral computed tomography (CT), patients aged 40–80 years with symptoms of anterior circulation acute ischaemic stroke were given 1.5
Grosset, D.G. +4 more
core +1 more source
Fermentation, fractionation and purification of streptokinase by chemical reduction method
Background and Objectives: Streptokinase is used clinically as an intravenous thrombolytic agent for the treatment of acute myocardial infarction and is commonly prepared from cultures of Streptococcus equisimilis strain H46A.
Z Karimi +4 more
doaj
Nonparametric Assessment of the Calibration of Individualized Treatment Effects
ABSTRACT An important aspect of the performance of algorithms that predict individualized treatment effects (ITEs) is moderate calibration, that is, the average treatment effect among individuals with predicted treatment effect of z being equal to z. The assessment of moderate calibration is a challenging task on two fronts: counterfactual responses ...
Mohsen Sadatsafavi +3 more
wiley +1 more source
The measurement of anti-streptokinase antibodies can distinguish the patients who may benefit from streptokinase and those who should be treated with some other thrombolytic regimen.
Afshin Afshari R. Elizbeth Holme
doaj
A multivalent bi‐specific nanoerythrosome (mBiNE@tPA) is developed as a “two‐birds‐one‐stone” platform that simultaneously exploits two principal thrombus components. By integrating erythrocyte membrane‐mediated homologous targeting with cRGD‐based active targeting to activated platelets, mBiNE@tPA achieves enhanced thrombus accumulation, triggered ...
Yu Huang +10 more
wiley +1 more source
ABSTRACT Ischiorectal abscess can rarely progress beyond the anorectal region to cause Fournier's gangrene, supralevator extension, and purulent peritonitis. Early recognition of disease progression, prompt imaging, aggressive surgical source control, and multidisciplinary management are critical to reducing morbidity and mortality in this life ...
Hervé Tshikomba Mbuyamba +7 more
wiley +1 more source
Activity Regulation by Fibrinogen and Fibrin of Streptokinase from Streptococcus Pyogenes. [PDF]
Streptokinase is a virulence factor of streptococci and acts as a plasminogen activator to generate the serine protease plasmin which promotes bacterial metastasis.
Sian Huish +2 more
doaj +1 more source
A type of illness known as cardiovascular disease affects the heart or blood arteries. The flow of blood to the heart, brain, or body is reduced due to thrombosis (blood clotting).
Maryam Maryam +3 more
doaj +1 more source
AEG‐AESPANC‐OPGE‐SIED‐SPG Ibero‐Latin American Guidelines on Acute Pancreatitis (iLATAM‐AP)
ABSTRACT Introduction Acute pancreatitis (AP) is a major cause of gastrointestinal hospitalizations worldwide. Although typically self‐limiting, up to one‐third of cases develop complications associated with increased morbidity and mortality. Despite recent advances that have improved outcomes, clinical heterogeneity necessitates updated, evidence ...
Karina Cárdenas‐Jaén +44 more
wiley +1 more source
Liposomes for the delivery of streptokinase
Streptokinase is an efficient thrombolytic agent used to treat thromboembolic disorders. Conventional streptokinase formulations have limited thrombolytic activity and several shortcomings because of their immunogenicity and dose-related side effects ...
Shivani Verma +2 more
core +1 more source

