Results 41 to 50 of about 4,363 (145)

A pilot study of streptokinase for acute cerebral infarction

open access: yes, 1995
We evaluated intravenous streptokinase in the treatment of cerebral infarction. Following neurological assessment and cerebral computed tomography (CT), patients aged 40–80 years with symptoms of anterior circulation acute ischaemic stroke were given 1.5
Grosset, D.G.   +4 more
core   +1 more source

Fermentation, fractionation and purification of streptokinase by chemical reduction method

open access: yesIranian Journal of Microbiology, 2011
Background and Objectives: Streptokinase is used clinically as an intravenous thrombolytic agent for the treatment of acute myocardial infarction and is commonly prepared from cultures of Streptococcus equisimilis strain H46A.
Z Karimi   +4 more
doaj  

Nonparametric Assessment of the Calibration of Individualized Treatment Effects

open access: yesStatistics in Medicine, Volume 45, Issue 20-22, September 2026.
ABSTRACT An important aspect of the performance of algorithms that predict individualized treatment effects (ITEs) is moderate calibration, that is, the average treatment effect among individuals with predicted treatment effect of z being equal to z. The assessment of moderate calibration is a challenging task on two fronts: counterfactual responses ...
Mohsen Sadatsafavi   +3 more
wiley   +1 more source

The Effect of Recombinant Tissue Plasminogen Activator (r-tPA) on Quantitation of Neutralising Anti-Streptokinase Antibodies

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2004
The measurement of anti-streptokinase antibodies can distinguish the patients who may benefit from streptokinase and those who should be treated with some other thrombolytic regimen.
Afshin Afshari R. Elizbeth Holme
doaj  

Multivalent Bi‐Specific Nanoerythrosomes: A Two‐Birds‐One‐Stone Approach to Combine Homologous and Active Targeting for Effective Thrombolysis

open access: yesSmall, Volume 22, Issue 47, 21 August 2026.
A multivalent bi‐specific nanoerythrosome (mBiNE@tPA) is developed as a “two‐birds‐one‐stone” platform that simultaneously exploits two principal thrombus components. By integrating erythrocyte membrane‐mediated homologous targeting with cRGD‐based active targeting to activated platelets, mBiNE@tPA achieves enhanced thrombus accumulation, triggered ...
Yu Huang   +10 more
wiley   +1 more source

Fournier's Gangrene and Purulent Peritonitis as a Result of Progressing Ischiorectal Abscess: A Case Report From Muhimbili National Hospital, Tanzania

open access: yesClinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Ischiorectal abscess can rarely progress beyond the anorectal region to cause Fournier's gangrene, supralevator extension, and purulent peritonitis. Early recognition of disease progression, prompt imaging, aggressive surgical source control, and multidisciplinary management are critical to reducing morbidity and mortality in this life ...
Hervé Tshikomba Mbuyamba   +7 more
wiley   +1 more source

Activity Regulation by Fibrinogen and Fibrin of Streptokinase from Streptococcus Pyogenes. [PDF]

open access: yesPLoS ONE, 2017
Streptokinase is a virulence factor of streptococci and acts as a plasminogen activator to generate the serine protease plasmin which promotes bacterial metastasis.
Sian Huish   +2 more
doaj   +1 more source

An In-Vivo Study: Development of Immobilized Fe3O4 Magnetic Streptokinase Nanoparticles Purified from Streptococus Pyogenes Ebl-48 to Enhance the Drug Delivery

open access: yesJournal of Pharmaceutical Research
A type of illness known as cardiovascular disease affects the heart or blood arteries. The flow of blood to the heart, brain, or body is reduced due to thrombosis (blood clotting).
Maryam Maryam   +3 more
doaj   +1 more source

AEG‐AESPANC‐OPGE‐SIED‐SPG Ibero‐Latin American Guidelines on Acute Pancreatitis (iLATAM‐AP)

open access: yesUnited European Gastroenterology Journal, Volume 14, Issue 5, June 2026.
ABSTRACT Introduction Acute pancreatitis (AP) is a major cause of gastrointestinal hospitalizations worldwide. Although typically self‐limiting, up to one‐third of cases develop complications associated with increased morbidity and mortality. Despite recent advances that have improved outcomes, clinical heterogeneity necessitates updated, evidence ...
Karina Cárdenas‐Jaén   +44 more
wiley   +1 more source

Liposomes for the delivery of streptokinase

open access: yes, 2017
Streptokinase is an efficient thrombolytic agent used to treat thromboembolic disorders. Conventional streptokinase formulations have limited thrombolytic activity and several shortcomings because of their immunogenicity and dose-related side effects ...
Shivani Verma   +2 more
core   +1 more source

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