Results 31 to 40 of about 13,759 (198)

Nonparametric Assessment of the Calibration of Individualized Treatment Effects

Statistics in Medicine, Volume 45, Issue 20-22, September 2026.
ABSTRACT An important aspect of the performance of algorithms that predict individualized treatment effects (ITEs) is moderate calibration, that is, the average treatment effect among individuals with predicted treatment effect of z being equal to z. The assessment of moderate calibration is a challenging task on two fronts: counterfactual responses ...
Mohsen Sadatsafavi, Jeroen Hoogland, Thomas P. A. Debray, John Petkau   +3 more
wiley   +1 more source

A study of empyema thoracis and role of intrapleural streptokinase in its management

BMC Infectious Diseases, 2004
Background Clinical spectrum, microbiology and outcome of empyema thoracis are changing. Intrapleural instillation of fibrinolytic agents is being increasingly used for management of empyema thoracis.
Dey AB, Sharma SK, Khilnani GC, Banga Amit, Wig Naveet, Banga Namrata   +5 more
doaj   +1 more source

Multivalent Bi‐Specific Nanoerythrosomes: A Two‐Birds‐One‐Stone Approach to Combine Homologous and Active Targeting for Effective Thrombolysis

Small, Volume 22, Issue 47, 21 August 2026.
A multivalent bi‐specific nanoerythrosome (mBiNE@tPA) is developed as a “two‐birds‐one‐stone” platform that simultaneously exploits two principal thrombus components. By integrating erythrocyte membrane‐mediated homologous targeting with cRGD‐based active targeting to activated platelets, mBiNE@tPA achieves enhanced thrombus accumulation, triggered ...
Yu Huang, Yilin Yang, Nicole Henry, Boram Gu, Jiahua Wang, Yuanyuan Guo, Colin Longstaff, Simon A. Thom, Yuehua Li, Xiao Yun Xu, Rongjun Chen   +10 more
wiley   +1 more source

Liposomes for the delivery of streptokinase

, 2017
Streptokinase is an efficient thrombolytic agent used to treat thromboembolic disorders. Conventional streptokinase formulations have limited thrombolytic activity and several shortcomings because of their immunogenicity and dose-related side effects ...
Shivani Verma, Bhuvaneshwar Vaidya, Lalit Kumar   +2 more
core   +1 more source

A comparative study on the effect of streptokinase between diabetic and non-diabetic myocardial infarction patients [PDF]

Bangladesh Journal of Pharmacology, 2008
A prospective interventional study was carried out to compare the thrombolytic effect of streptokinase between diabetic and non-diabetic myocardial infarction patients.
Md. Anup Rahman Chowdhury, A. K. M. Mosharrof Hossain, Sudhangshu Ranjan Dey, A. K. M. Akhtaruzzaman, Nur-A-Farhana Islam   +4 more
doaj   +2 more sources

Fournier's Gangrene and Purulent Peritonitis as a Result of Progressing Ischiorectal Abscess: A Case Report From Muhimbili National Hospital, Tanzania

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Ischiorectal abscess can rarely progress beyond the anorectal region to cause Fournier's gangrene, supralevator extension, and purulent peritonitis. Early recognition of disease progression, prompt imaging, aggressive surgical source control, and multidisciplinary management are critical to reducing morbidity and mortality in this life ...
Hervé Tshikomba Mbuyamba, Rajabu Athumani Bakari, Charles Oswald Ruboha, Alfred Chibwae, Kelvin Richard Martin, Boniface Kahindi Kazungu, Ahmed Abubakar Ahmed, Daniel William Kitua   +7 more
wiley   +1 more source

Activation of rabbit plasminogen by streptokinase

, 1965
When streptokinase was injected into whole rabbits the fibrinolytic and proteolytic activity of the plasma increased and antifibrinolytic and antiproteolytic activity and fibrinogen level fell.
Dhurjati P. Chattopadhyay, Eugene E. Cliffton   +1 more
core   +1 more source

AEG‐AESPANC‐OPGE‐SIED‐SPG Ibero‐Latin American Guidelines on Acute Pancreatitis (iLATAM‐AP)

United European Gastroenterology Journal, Volume 14, Issue 5, June 2026.
ABSTRACT Introduction Acute pancreatitis (AP) is a major cause of gastrointestinal hospitalizations worldwide. Although typically self‐limiting, up to one‐third of cases develop complications associated with increased morbidity and mortality. Despite recent advances that have improved outcomes, clinical heterogeneity necessitates updated, evidence ...
Karina Cárdenas‐Jaén, Lucía Guilabert, Emma Martínez‐Moneo, Carla Mancilla, Miguel Bispo, Pedro Moutinho‐Ribeiro, Rodrigo Mansilla, Andreia Rei, Ana García García de Paredes, Antonio López‐Serrano, Bruno Rosa, Claudia Sánchez‐Marín, Daniel de la Iglesia, Edson Guzmán‐Calderon, Eduardo Rodrigues‐Pinto, Eva Marín‐Serrano, Fabio Ausania, Fauze Maluf‐Filho, Guido Villagómez, Humberto Cristino, Isabel Pascual‐Moreno, José A. Gonzalez, José M. Ramia, João Lopes‐Delgado, Lucas Granero, Mario Peláez‐Luna, María Francisco, Natalia Corzo‐Zamora, Ricardo Rio‐Tinto, Rómulo D. Vargas, Sandra Basso, Susana Lopes, Susana Marques, William Manzanares, Zoltán Berger, Irene Carrillo, José Joaquín Mira‐Solves, Alberto Espino, Adriana Cowdin, Alejandro Piscoya, Alexandra Fernandes, Noelia Rodríguez‐Ferreiro, Neftalí Jara Pérez‐López, Beatriz Valero, Enrique de‐Madaria   +44 more
wiley   +1 more source

The Effect of Recombinant Tissue Plasminogen Activator (r-tPA) on Quantitation of Neutralising Anti-Streptokinase Antibodies

Iranian Journal of Allergy, Asthma and Immunology, 2004
The measurement of anti-streptokinase antibodies can distinguish the patients who may benefit from streptokinase and those who should be treated with some other thrombolytic regimen.
Afshin Afshari R. Elizbeth Holme
doaj  

Drug‐Free Thrombolysis Mediated by Physically Activated Micro/Nanoparticles

Advanced Functional Materials, Volume 36, Issue 34, 27 April 2026.
Overview of particle‐mediated thrombolytic effects (thermal, mechanical, and chemical) and their activating physical stimuli (light, ultrasound, and magnetic field) in drug‐free thrombolysis. ABSTRACT Thrombus‐associated disorders rank among the world's leading causes of death, with ischemic heart disease and stroke as the main contributors.
Pierre Sarfati, Yoann Lalatonne, Cédric Chauvierre   +2 more
wiley   +1 more source