Results 51 to 60 of about 136,149 (288)
Preventing Candida albicans from subverting host plasminogen for invasive infection treatment
Emerging Microbes and Infections, 2020 Candida albicans is a common fungal pathogen in humans that colonizes the skin and mucosal surfaces of the majority healthy individuals. How C.
Si-Min Chen +10 more
doaj +1 more source
Proteolyzed Variant of IgG with Free C-Terminal Lysine as a Biomarker of Prostate Cancer
Biology, 2021 The differential diagnosis of prostate cancer is problematic due to the lack of markers with high diagnostic accuracy. We previously demonstrated the increased binding of IgG to human plasminogen (PLG) in plasma of patients with prostate cancer (PC ...
Anna Lokshin +10 more
doaj +1 more source
Modulation of neuronal plasticity by extracellular serine proteases and their inhibitors : proteolytic control of NMDA receptors [PDF]
, 2004 Serine proteases are enzymes catalyzing protein cleavage. Because of their capability to cleave a wide variety of substrates, they are involved in many critical physiological processes such as digestion, hemostasis, reproduction and immune response, as ...
Kvajo, Mirna
core +1 more source
Laureates of the Palladin Prize of the National Academy of Sciences of Ukraine (1985–1986) [PDF]
The Ukrainian Biochemical Journal, 2013 The article presents the information about the life and scientific activity of the Palladin Prize laureats. In 1985, S. O. Kudinov was awarded the Prize for his monograph ”Ca2+ transport systems in nerve cells”. In 1986, A. Ya. Rozanov, A.
R. P. Vynogradova, V. M. Danilova
doaj +1 more source
Plasminogen activators and plasminogen activator inhibitors in endometriosis
Frontiers in Bioscience, 2005 Endometriosis is one of the most frequent benign gynecological diseases that affect women. Little is known about the pathogenesis and etiology of endometriosis, despite the numerous studies performed in this field. Although endometriosis is a benign disease, the endometrial tissue, after attachment to the peritoneum, has the ability to grow and invade ...
Gilabert-Estelles, J +6 more
openaire +3 more sources
Clinical Chemistry, 1968 Abstract An indirect caseinolytic assay for plasminogen utilizing acid-treated plasma or serum and optimal concentrations of streptokinase is described. A linear response to increasing plasma or serum concentrations was observed. An acid-treated plasma or serum sample is preferable to euglobulin.
openaire +2 more sources
Interaction of plasminogen and fibrin in plasminogen activation.
Journal of Biological Chemistry, 1990 Glu1-, Lys77-, miniplasminogens, kringle 1-3, kringle 1-5A, and kringle 1-5R were able to bind with fibrin, while microplasminogen and kringle 4 did not bind significantly. Kringle 1-5A, but not kringle 1-3, effectively inhibited the binding of Glu1-, Lys77-, and miniplasminogens with fibrin.
H L, Wu +6 more
openaire +2 more sources
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Plasminogen-Loaded Fibrin Scaffold as Drug Delivery System for Wound Healing Applications
Pharmaceutics, 2022 Plasminogen is a protein involved in intravascular and extravascular fibrinolysis, as well as in wound healing, cell migration, tissue formation and angiogenesis.
Tamer Al Kayal +5 more
doaj +1 more source