Results 71 to 80 of about 136,538 (301)

Mechanical Stability and Fibrinolytic Resistance of Clots Containing Fibrin, DNA, and Histones [PDF]

, 2013
Neutrophil extracellular traps are networks of DNA and associated proteins produced by nucleosome release from activated neutrophils in response to infection stimuli and have recently been identified as key mediators between innate immunity, inflammation,
Szabó, László, Szab , L., Hoell, Armin, Kolev, Krasimir, Sótonyi, Péter, Longstaff, C., Longstaff C, Krumrey, M., Komorowicz, E., Longstaff, Colin, Varjú, Imre, Kolev, K., Varga, Z., Kolev, Kraszimir Nikolaev, Komorowicz, Erzsébet, Krumrey, Michael, Hoell A, S tonyi, P., Krumrey M, Varju, I., Hoell, A., Bóta, Attila, Varga, Zoltán, B ta, A.   +23 more
core   +1 more source

Reperfusion‐Dependent Outcomes After Endovascular Thrombectomy Stratified by NIHSS‐ASPECTS Clinical‐Core Mismatch

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This analysis evaluates the effect of successful reperfusion on functional outcomes after MT, stratified by admission National Institutes of Health Stroke Scale (NIHSS) and Alberta Stroke Program Early CT Score (ASPECTS) as surrogates for clinical‐core mismatch, using multicenter registry data.
Felix Schlicht, Lukas Meyer, Gabriel Broocks, Matthias Bechstein, Christian Thaler, Christian Heitkamp, Laurens Winkelmeier, Vincent Geest, Alexander Heitkamp, Maximilian Jungnitz, Gregor Peter, Luca Meucci, Tobias Faizy, Jawed Nawabi, Caspar Brekenfeld, Fabian Flottmann, Maximilian Schell, Alexandros Hadjilaou, Uta Hanning, Götz Thomalla, Jens Fiehler, Susanne Gellißen, Helge C. Kniep, for the German Stroke Registry Endovascular Treatment, (GSR‐ET) Alexander Nave, Anna Alegiani, Annerose Mengel, Arno Reich, Bernd Eckert, Charlotte Pietrock, Christian Nolte, Eberhard Siebert, Fabian Flottmann, Fee Keil, Franziska Dorn, Gabor Petzold, Götz Thomalla, Hanna Zimmermann, Jan Borggrefe, Jan Hendrik Schäfer, Jens Fiehler, Joachim Röther, Klaus Gröschel, Lars Kellert, Mario Abruscato, Maximilian Schell, Omid Nikoubashman, Peter Schellinger, Silke Wunderlich, Steffen Tiedt, Sven Thonke, Timo Uphaus, Tobias Boeckh‐Behrens, Ulrike Ernemann   +53 more
wiley   +1 more source

The Deleterious Effects of Impaired Fibrinolysis on Skeletal Development Are Dependent on Fibrin(ogen), but Independent of Interlukin-6

Frontiers in Cardiovascular Medicine, 2021
Chronic diseases in growing children, such as autoimmune disorders, obesity, and cancer, are hallmarked by musculoskeletal growth disturbances and osteoporosis.
Heather A. Cole, Stephanie N. Moore-Lotridge, Stephanie N. Moore-Lotridge, Gregory D. Hawley, Richard Jacobson, Richard Jacobson, Masato Yuasa, Masato Yuasa, Leslie Gewin, Leslie Gewin, Jeffry S. Nyman, Jeffry S. Nyman, Jeffry S. Nyman, Jeffry S. Nyman, Matthew J. Flick, Matthew J. Flick, Matthew J. Flick, Jonathan G. Schoenecker, Jonathan G. Schoenecker, Jonathan G. Schoenecker, Jonathan G. Schoenecker, Jonathan G. Schoenecker, Jonathan G. Schoenecker   +22 more
doaj   +1 more source

Inhibition of thiol isomerase activity diminishes endothelial activation of plasminogen, but not of protein C [PDF]

, 2015
Highlights •A range of thiol isomerase enzymes were expressed by HMEC-1 endothelial cells. •Inhibition of thiol isomerases reduced plasminogen activation on HMEC-1 cells.
Smith, C.L., Shah, C.M., Gordge, M.P., Kamaludin, N.   +3 more
core   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk, Marcel Pilarek, Emilia Jaworska, Natalia Kardas, Oliwia Barnaś, Julia Woźniak, Iga Machała, Julia Węgrzynek‐Gallina, Joanna Siuda, Anna Hawrot‐Kawecka, Anetta Lasek‐Bal   +10 more
wiley   +1 more source

Hemostasis protein-coding genes, peripheral hemostasis parameters, and atherothrombosis predisposition in patients with cardiovascular disease

Кардиоваскулярная терапия и профилактика, 2011
Aim. To study the associations between polymorphic variants of hemostasis protein-coding genes, hemostasis system functioning, and atherothrombosis development in patients with cardiovascular disease (CVD). Material and methods.
G. I. Lifshits, S. T. Danilkina, E. V. Guskova, E. N. Voronina, M. L. Filipenko   +4 more
doaj   +1 more source

Multimodal therapy for synergic inhibition of tumour cell invasion and tumour-induced angiogenesis [PDF]

, 2010
Background: Squamous cell carcinoma of the head and neck (SCCHN) are highly invasive tumours with frequent local and distant recurrence. Metastasis formation requires degradation of the extracellular matrix, which is fulfilled by membrane-associated ...
Olivier Gires, Muehlenweg Bernd, Pamela Zengel, Muehlenweg, Bernd, Gires, Olivier, Ramp, D., Gires, O., Alexander Berghaus, Gires Olivier, Mack, Brigitte, Zengel, Pamela, Zahler, Stefan, Muehlenweg, B., Diana Ramp, Stefan Zahler, Mack, B., Bernd Muehlenweg, Zahler, S., Berghaus Alexander, Mack Brigitte, Zengel, P., Suna Schmitz, Berghaus, Alexander, Schmitz, Suna, Schmitz, S., Ramp, Diana, Schmitz Suna, Zahler Stefan, Zengel Pamela, Brigitte Mack, Ramp Diana, Berghaus, A.   +31 more
core   +1 more source

Comprehensive Assessment of Arterial, Tissue, and Venous Collaterals for Evaluating the Infarct Growth Rate: The Multimodal Collateral Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto, Umberto Pensato, Ilaria Casetta, Giorgio U. Marcello, Angelo Barra, Anna Poggesi, Edoardo Carlesi, Sara Mancini, Andrea Ginestroni, Vittorio Miele, Alessandro Padovani, Andrea Morotti, Enrico Fainardi   +12 more
wiley   +1 more source

High resolution nuclear magnetic resonance studies of kringle containing proteins [PDF]

, 1983
The kringle is a name given to a sequence of seventy nine residues linked by three disulphide bridges, multiple copies of which have been found in a number of proteins involved in haemostasis.
Pluck, N. D., Pluck, Nigel. D., Pluck, N.D.   +2 more
core   +2 more sources

Cross‐Scale Hierarchical Targeted Delivery System Based on Small‐Scale Magnetic Robots

Advanced Robotics Research, EarlyView.
This article reviews a cross‐scale hierarchical targeted delivery system that integrates magnetic continuum robots and magnetic microrobots. By combining rapid long‐range navigation with precise microscale targeting, the system overcomes key limitations of single‐scale approaches.
Junjian Zhou, Zhiqiang Chen, Yuanbiao Ma, Zhiqiang Tang, Qianqian Wang   +4 more
wiley   +1 more source