Results 91 to 100 of about 147,856 (201)

Effect of lipopolysaccharide from periodontal pathogens on the production of tissue plasminogen activator and plasminogen activator inhibitor 2 by human gingival fibroblasts

, 2001
The definitive version is available at www.blackwell-synergy.comBoth tissue plasminogen activator (t-PA) and plasminogen activator inhibitor 2 (PAI-2) are important proteolysis factors present in inflamed human periodontal tissues. The aim of the present
Xiao, Y., Bunn, Clive L, Bartold, P., Xiao, Yin, Bartold, P.Mark, Bunn, C.   +5 more
core   +1 more source

The Desmoteplase In Acute Ischemic Stroke Trial (DIAS): a phase II MRI-based 9-hour window acute stroke thrombolysis trial with intravenous desmoteplase [PDF]

, 2005
<p><b>Background and Purpose:</b> Most acute ischemic stroke patients arrive after the 3-hour time window for recombinant tissue plasminogen activator (rtPA) administration.
Fischer, M., Eliasziw, M., Lees, K.R., Kaste, M., Albers, G., Al, R.Y., Hacke, W., Furlan, A., Soehngen, M., Warach, S.   +9 more
core   +1 more source

Dose escalation of desmoteplase for acute ischemic stroke (DEDAS): evidence of safety and efficacy 3 to 9 hours after stroke onset [PDF]

, 2006
<p><b>Background and Purpose:</b> Desmoteplase is a novel plasminogen activator with favorable features in vitro compared with available agents.
Lees, K.R., Hacke, W.l, Sachara, C., Rowley, H.A., Furlan, A.J., Al, R.Y., Eyding, D., Albers, G.W., Soehngen, M., Warach, S.   +9 more
core   +1 more source

Causal association of plasminogen activators and their inhibitors with Alzheimer’s disease: a Mendelian randomization study

Introduction Alzheimer’s disease (AD) is the most common cause of dementia and contributes to a huge burden of disease worldwide. Observational studies have found that tissue plasminogen activator (t-PA) inhibits the development of AD, but little is ...
Xin Guo, Baolong Pan, Fangyu Gao, Jingsi Zhang, Feng Gao, Shanshan Wang, Qiao Niu   +6 more
core   +1 more source

Baccharis articulata aqueous extract exerts in vitro antifibrotic effect in hepatic stellate cells by attenuating collagen deposition and TGF-β1 protein expression

EXCLI Journal : Experimental and Clinical Sciences
Baccharis articulata (Lam) Pers. is an herb native to southern Brazil and is widely used in local traditional medicine for weight loss and for the treatment of digestive and liver diseases.
Daiana Daniele Boeff, Markus Berger, Mariana Koetz, Pamela Zanon, Alícia da Costa Pereira, Katyuce de Souza Farias, Carlos Alexandre Carollo, Paula Barros Terraciano, Eduardo Luis Konrath   +8 more
doaj   +1 more source

Synergy between HA cleavage site sequence and NA-mediated plasminogen recruitment as a virulence mechanism for low-pathogenic avian influenza

mBio
An outbreak of H3N1 low-pathogenic avian influenza virus (LPAIV) in Belgium in 2019 caused unexpected levels of mortality and morbidity in poultry. These viruses possess an NA polymorphism associated with plasminogen (PLG) binding, as well as an atypical
Hui Min Lee, Kate Sutton, William Harvey, Samantha Sives, Rute Maria Pinto, Eleanor Gaunt, Samantha Lycett, Sjaak de Wit, Lonneke Vervelde, Paul Digard   +9 more
doaj   +1 more source

Plasminogen Receptors

Journal of Biomedicine and Biotechnology, 2012
Miles, Lindsey A., Plow, Edward F., Waisman, David M., Parmer, Robert J.   +3 more
openaire   +2 more sources

Effects of pulse-therapy on natural anticoagulant system of the endothelium in nonspecific aortoarteritis

Терапевтический архив, 2003
Aim. To investigate the influence of pulse-therapy on anticoagulant system of the endothelium in patients with nonspecific aortoarteritis. Material and methods. Eleven patients (9 females and 2 males, mean age 33.4 ± 8.8 years, the disease duration 5.8 ±
M S Guryeva, A A Baranov, S V Bagrakova, E L Nasonov, D G Zharikova   +4 more
doaj  

Plasminogen activator inhibitors

, 1987
Chemicals/CAS: fibrin, 9001-31-4; plasminogen activator inhibitor, 105844-41-5; plasminogen activator, 9039-53-6; Carrier Proteins; Glycoproteins; Plasminogen Activators, EC 3.4.21.-; Plasminogen Inactivators; Protease Inhibitors; protease ...
Sprengers, E.D., Kluft, C.
core  

Plain language summary: How safe and effective is long-term treatment with intravenous plasminogen concentrate for people with type 1 plasminogen deficiency? [PDF]

Ther Adv Hematol
Shapiro AD, McDaniel H, Decker RW, Nakar C, Lorber J, Thukral N, Parker JM, Thibaudeau K.   +7 more
europepmc   +1 more source