Results 101 to 110 of about 151,729 (305)

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler   +4 more
wiley   +1 more source

Plasminogen interaction with Trypanosoma cruzi [PDF]

open access: yes, 2004
The ability of Trypanosoma cruzi to interact with plasminogen, the zimogenic form of the blood serin protease plasmin, was examined. Immunohistochemistry studies revealed that both forms, epimastigotes and metacyclic trypomastigotes, were able to fix ...
Laura Almeida   +4 more
core   +1 more source

The Use of Low-Dose Recombinant Tissue Plasminogen Activator to Treat a Preterm Infant with an Intrauterine Spontaneous Arterial Thromboembolis

open access: yesTurkish Journal of Hematology, 2015
Neonatal thromboembolic events are rare, and only a few cases of intrauterine spontaneous arterial thromboembolisms have been reported in the literature.
Yaşar Demirelli   +3 more
doaj   +1 more source

Plasminogen activator inhibitors

open access: yes, 1987
Chemicals/CAS: fibrin, 9001-31-4; plasminogen activator inhibitor, 105844-41-5; plasminogen activator, 9039-53-6; Carrier Proteins; Glycoproteins; Plasminogen Activators, EC 3.4.21.-; Plasminogen Inactivators; Protease Inhibitors; protease ...
Sprengers, E.D., Kluft, C.
core  

Causal correlations between inflammatory proteins and heart failure: A two‐sample Mendelian randomization analysis

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1374-1385, April 2025.
Abstract Aims Inflammation plays a critical role in both the development and progression of heart failure (HF), which is a leading cause of morbidity and mortality worldwide. However, the causality between specific inflammation‐related proteins and HF risk remains unclear.
Xian‐Guan Zhu   +9 more
wiley   +1 more source

An immunohistochemical study of the distribution of plasminogen and plasminogen activators in bullous pemphigoid.

open access: yes, 2016
Abnormalities of the cutaneous plasminogen/plasminogen activator system have been associated with acantholytic disorders, psoriasis, keratinocytes in culture, and epidermis in healing wounds.

core   +1 more source

Identification of a novel regulatory mechanism for the disease associated protein, uPAR [PDF]

open access: yes, 2014
Expression quantitative trait loci (eQTLs), as determined through a series of statistical association studies collectively known as genome-wide association (GWA) studies, have provided us with a hypothesis free approach for the investigation into ...
Portelli, Michael A.   +2 more
core  

Pharmacological pain relief and postpartum bleeding in women with moderate or severe anemia: A cohort analysis of the WOMAN‐2 trial

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Pain relief could minimize blood loss by limiting the adrenaline stress response to fear and trauma during birth. We examined the association between pharmacological pain relief and postpartum bleeding in a large cohort of women giving birth with anemia in sub‐Saharan Africa and South Asia.
Judith Lieber   +161 more
wiley   +1 more source

Human biomarker navigator

open access: yesiMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

Plasminogen Has a Broad Extrahepatic Distribution

open access: yes, 2002
SummaryPlasmin is the major enzyme that dissolves fibrin in the vasculature and the predominant source of its zymogen, plasminogen, is liver. However, plasmin has a broad substrate spectrum and, if present in other tissues, may perform additional ...
Bruce Fowler   +7 more
core   +1 more source

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