Application of Multiharmonic QCM-D for Detection of Plasmin at Hydrophobic Surfaces Modified by β-Casein [PDF]
Chemosensors, 2022 Plasmin protease plays an important role in many processes in living systems, including milk. Monitoring plasmin activity is important for control of the nutritional quality of milk and other dairy products.
Sandro Spagnolo +3 more
doaj +2 more sources
Plasmin Regulation through Allosteric, Sulfated, Small Molecules [PDF]
Molecules, 2015 Plasmin, a key serine protease, plays a major role in clot lysis and extracellular matrix remodeling. Heparin, a natural polydisperse sulfated glycosaminoglycan, is known to allosterically modulate plasmin activity.
Rami A. Al-Horani +3 more
doaj +5 more sources
Plasmin–Plasminogen System and Milk Physicochemical Traits in Intensively Reared Chios and Frizarta Ewes: Effects of Lactation Stage, Age, and Somatic Cell Count [PDF]
AnimalsThe objective of the present study is to evaluate the effects of lactation stage, age, somatic cell count (SCC), and daily milk yield on plasmin–plasminogen (PL–PG) system activity and physicochemical milk traits in intensively reared Chios and Frizarta ...
Aphrodite I. Kalogianni +4 more
doaj +2 more sources
Recent Advances in Milk Plasmin and Factors Affecting Its Activity [PDF]
Shipin Kexue, 2023 Plasmin is an important factor affecting the shelf-life quality of milk products, and its hydrolytic activity is regulated by many factors, such as activators, inhibitors, and activator inhibitors.
YANG Jinhui, QIAN Wentao, LI Hongliang, WANG Menghui, ZHAO Jingru, REN Xiaomin
doaj +1 more source
Tranexamic acid impairs plasmin generation on human mesenchymal stem cells and derived membrane microvesicles, halting pericellular proteolysis [PDF]
Frontiers in MedicineIntroductionMesenchymal stem cells (MSCs) participate in the dynamic remodeling of the extracellular matrix during wound healing, natural bleeding processes or cancer progression.
Ramy Abou Rjeily +6 more
doaj +2 more sources
Gender affects skin wound healing in plasminogen deficient mice. [PDF]
PLoS ONE, 2013 The fibrinolytic activity of plasmin plays a fundamental role in resolution of blood clots and clearance of extravascular deposited fibrin in damaged tissues.
Birgitte Rønø +3 more
doaj +1 more source
Plasmin plays an essential role in amplification of psoriasiform skin inflammation in mice. [PDF]
PLoS ONE, 2011 BACKGROUND:Although increased levels of plasminogen activators have been found in psoriatic lesions, the role of plasmin converted from plasminogen by plasminogen activators in pathogenesis of psoriasis has not been investigated.
Qun Li +8 more
doaj +1 more source
Induction of brain microvascular endothelial cell urokinase expression by Cryptococcus neoformans facilitates blood-brain barrier invasion. [PDF]
PLoS ONE, 2012 The invasive ability of the blood-borne fungal pathogen Cryptococcus neoformans can be enhanced through interactions with host plasma components, such as plasminogen.
Jamal Stie, Deborah Fox
doaj +1 more source
Plasmin drives burn-induced systemic inflammatory response syndrome
JCI Insight, 2021 Severe injuries, such as burns, provoke a systemic inflammatory response syndrome (SIRS) that imposes pathology on all organs. Simultaneously, severe injury also elicits activation of the fibrinolytic protease plasmin. While the principal adverse outcome
Breanne H. Y. Gibson +8 more
doaj +1 more source
Unexpected timely fracture union in matrix metalloproteinase 9 deficient mice. [PDF]
PLoS ONE, 2018 Immediately following a fracture, a fibrin laden hematoma is formed to prevent bleeding and infection. Subsequently, the organized removal of fibrin, via the protease plasmin, is essential to permit fracture repair through angiogenesis and ossification ...
Masato Yuasa +10 more
doaj +1 more source