Results 11 to 20 of about 30,314 (207)
Inhibition of plasmin by fibrinogen [PDF]
Biochemical Journal, 1990 The kinetics of inhibition of the amidolytic activity of plasmin on D-Val-L-Leu-L-Lys p-nitroanilide hydrochloride (S-2251) by fibrinogen and fibrin were determined. Reciprocal (1/v versus 1/[S]) plots of plasmin inhibition by 0.50 microM-fibrinogen showed a non-linear downward curve.
A A, Higazi, M, Mayer
openaire +2 more sources
Lens subluxation after plasmin and SF6 injections in rabbit eyes. [PDF]
PLoS ONE, 2014 To investigate the rate of lens subluxation following plasmin and/or SF6 injections in eyes, and whether a subsequent elevated level of vascular endothelial growth factor (VEGF) and vitreous tap would aggravate subluxation.Four groups of rabbits were ...
Wei-Chi Wu +8 more
doaj +1 more source
iScience, 2019 Summary: Dengue symptoms include alteration of blood coagulation and fibrinolysis, causing severe hemorrhage and death. Here, we demonstrate that higher concentration of plasmin, the human fibrinolytic factor, in blood meal enhances dengue virus (DENV ...
Karthik Ramesh +7 more
doaj +1 more source
Group B Streptococcus hijacks the host plasminogen system to promote brain endothelial cell invasion. [PDF]
PLoS ONE, 2013 Group B Streptococcus (GBS) is the leading cause of meningitis in neonates. We have previously shown that plasminogen, once recruited to the GBS cell surface and converted into plasmin by host-derived activators, leads to an enhancement of bacterial ...
Vanessa Magalhães +7 more
doaj +1 more source
Dendritic Cell-Mediated Phagocytosis but Not Immune Activation Is Enhanced by Plasmin. [PDF]
PLoS ONE, 2015 Removal of dead cells in the absence of concomitant immune stimulation is essential for tissue homeostasis. We recently identified an injury-induced protein misfolding event that orchestrates the plasmin-dependent proteolytic degradation of necrotic ...
Rachael J Borg +9 more
doaj +1 more source
Plasmin Regulation through Allosteric, Sulfated, Small Molecules
Molecules, 2015 Plasmin, a key serine protease, plays a major role in clot lysis and extracellular matrix remodeling. Heparin, a natural polydisperse sulfated glycosaminoglycan, is known to allosterically modulate plasmin activity.
Rami A. Al-Horani +3 more
doaj +1 more source
CALIX[4]ARENES METHYLENE BISPHOSPHONIC ACIDS EFFECT ON PLASMIN ACTIVITY [PDF]
Biotechnologia Acta, 2018 The aim of the work was to study plasmin inhibiting properties of calix[4]arenes functionalized by phosphonic acid remnants. The following methods were used: turbidimetry, analysis of enzyme activity for chromogenic substrates, evaluation of caseinolytic
O. I. Yusova +5 more
doaj +1 more source
Micromachines, 2021 We used the research quartz crystal microbalance (RQCM) to monitor regulatory effects of plasmin and trypsin in the presence of their inhibitor α2-antiplasmin.
Marek Tatarko +2 more
doaj +1 more source
Journal of Lipid Research, 2023 After feeding, adipose tissue lipoprotein lipase (LPL) activity should be maximized, therefore the potent LPL-inhibitory activity of angiopoietin-like protein 4 (ANGPTL4) must be blocked by ANGPTL8 through formation of ANGPTL4/8 complexes.
Yan Q. Chen +6 more
doaj +1 more source
Endoproteolysis of cellular prion protein by plasmin hinders propagation of prions
Frontiers in Molecular Neuroscience, 2022 Many questions surround the underlying mechanism for the differential metabolic processing observed for the prion protein (PrP) in healthy and prion-infected mammals.
Charles E. Mays +12 more
doaj +1 more source