Results 11 to 20 of about 39,772 (244)
A novel biosensor for measuring plasmin activity [PDF]
Research and Practice in Thrombosis and HaemostasisBackground: Plasmin facilitates fibrinolysis by catalyzing the degradation of fibrin clots. Reliable methods to assess fibrinolysis by measuring plasmin generation are needed in the preclinical and clinical settings.
Ying Dai +4 more
doaj +2 more sources
Does plasmin have anticoagulant activity?
Vascular Health and Risk Management, 2010 Jane Hoover-PlowJoseph J Jacobs Center for Thrombosis and Vascular Biology, Departments of Cardiovascular Medicine and Molecular Cardiology, Lerner Research Institute Cleveland Clinic, Ohio, USAAbstract: The coagulation and fibrinolytic pathways regulate
Jane Hoover-Plow
doaj +1 more source
Neutrophil Extracellular Traps Block Fibrinolysis in Ischemic Stroke. [PDF]
Ann NeurolObjectives Intravenous thrombolysis (IVT) failure in acute ischemic stroke (AIS) is frequent, but its causes remain elusive. We investigated whether biologically relevant intrathrombus concentrations of tissue plasminogen activator (tPA) were achieved in failed IVT and whether neutrophil extracellular traps (NETs) contributed to this therapeutic ...
Solo Nomenjanahary M +21 more
europepmc +2 more sources
Staphylococcus aureus proteins Sbi and Efb recruit human plasmin to degrade complement C3 and C3b [PDF]
, 2012 Upon host infection, the human pathogenic microbe Staphylococcus aureus (S. aureus) immediately faces innate immune reactions such as the activated complement system. Here, a novel innate immune evasion strategy of S. aureus is described.
Peter F. Zipfel +25 more
core +1 more source
The plasmin-antiplasmin system: structural and functional aspects [PDF]
, 2010 The plasmin-antiplasmin system plays a key role in blood coagulation and fibrinolysis. Plasmin and (2)-antiplasmin are primarily responsible for a controlled and regulated dissolution of the fibrin polymers into soluble fragments.
Johann Schaller +5 more
core +2 more sources
Lens subluxation after plasmin and SF6 injections in rabbit eyes. [PDF]
PLoS ONE, 2014 To investigate the rate of lens subluxation following plasmin and/or SF6 injections in eyes, and whether a subsequent elevated level of vascular endothelial growth factor (VEGF) and vitreous tap would aggravate subluxation.Four groups of rabbits were ...
Wei-Chi Wu +8 more
doaj +1 more source
iScience, 2019 Summary: Dengue symptoms include alteration of blood coagulation and fibrinolysis, causing severe hemorrhage and death. Here, we demonstrate that higher concentration of plasmin, the human fibrinolytic factor, in blood meal enhances dengue virus (DENV ...
Karthik Ramesh +7 more
doaj +1 more source
Dendritic Cell-Mediated Phagocytosis but Not Immune Activation Is Enhanced by Plasmin. [PDF]
PLoS ONE, 2015 Removal of dead cells in the absence of concomitant immune stimulation is essential for tissue homeostasis. We recently identified an injury-induced protein misfolding event that orchestrates the plasmin-dependent proteolytic degradation of necrotic ...
Rachael J Borg +9 more
doaj +1 more source
Journal of Lipid Research, 2023 After feeding, adipose tissue lipoprotein lipase (LPL) activity should be maximized, therefore the potent LPL-inhibitory activity of angiopoietin-like protein 4 (ANGPTL4) must be blocked by ANGPTL8 through formation of ANGPTL4/8 complexes.
Yan Q. Chen +6 more
doaj +1 more source
CALIX[4]ARENES METHYLENE BISPHOSPHONIC ACIDS EFFECT ON PLASMIN ACTIVITY [PDF]
Biotechnologia Acta, 2018 The aim of the work was to study plasmin inhibiting properties of calix[4]arenes functionalized by phosphonic acid remnants. The following methods were used: turbidimetry, analysis of enzyme activity for chromogenic substrates, evaluation of caseinolytic
O. I. Yusova +5 more
doaj +1 more source