Results 11 to 20 of about 36,053 (249)
Plasmin inhibitors prevent leukocyte accumulation and remodeling events in the postischemic microvasculature. [PDF]
PLoS ONE, 2011 Clinical trials revealed beneficial effects of the broad-spectrum serine protease inhibitor aprotinin on the prevention of ischemia-reperfusion (I/R) injury. The underlying mechanisms remained largely unclear.
Christoph A Reichel +7 more
doaj +3 more sources
Plasmin Regulation through Allosteric, Sulfated, Small Molecules
Molecules, 2015 Plasmin, a key serine protease, plays a major role in clot lysis and extracellular matrix remodeling. Heparin, a natural polydisperse sulfated glycosaminoglycan, is known to allosterically modulate plasmin activity.
Rami A. Al-Horani +3 more
doaj +3 more sources
Does plasmin have anticoagulant activity?
Vascular Health and Risk Management, 2010 Jane Hoover-PlowJoseph J Jacobs Center for Thrombosis and Vascular Biology, Departments of Cardiovascular Medicine and Molecular Cardiology, Lerner Research Institute Cleveland Clinic, Ohio, USAAbstract: The coagulation and fibrinolytic pathways regulate
Jane Hoover-Plow
doaj +1 more source
Plasmin: indigenous milk proteinase
Mljekarstvo, 2002 The most important characteristic of plasmin, as significant indigenous milk proteinase, its concentration, concentration measuring procedure and activity of plasmin are described.
Samir Kalit +2 more
doaj +2 more sources
High Osmolarity Effect of Intravitreal Plasmin Enzyme on Rabbit Retina [PDF]
, 2015 2015-02We conducted a study of the effect of intravitreal plasmin on retinal thickness in rabbits. Forty rabbit eyes were injected with 0.4, 1, 2, and 5 IU of plasmin (8 eyes/group). The same volume of BSS-plus® was injected in control eyes. Four eyes in
ITO, YASUKI +4 more
core +1 more source
Inhibition of plasmin by fibrinogen [PDF]
Biochemical Journal, 1990 The kinetics of inhibition of the amidolytic activity of plasmin on D-Val-L-Leu-L-Lys p-nitroanilide hydrochloride (S-2251) by fibrinogen and fibrin were determined. Reciprocal (1/v versus 1/[S]) plots of plasmin inhibition by 0.50 microM-fibrinogen showed a non-linear downward curve.
A A, Higazi, M, Mayer
openaire +2 more sources
Lens subluxation after plasmin and SF6 injections in rabbit eyes. [PDF]
PLoS ONE, 2014 To investigate the rate of lens subluxation following plasmin and/or SF6 injections in eyes, and whether a subsequent elevated level of vascular endothelial growth factor (VEGF) and vitreous tap would aggravate subluxation.Four groups of rabbits were ...
Wei-Chi Wu +8 more
doaj +1 more source
iScience, 2019 Summary: Dengue symptoms include alteration of blood coagulation and fibrinolysis, causing severe hemorrhage and death. Here, we demonstrate that higher concentration of plasmin, the human fibrinolytic factor, in blood meal enhances dengue virus (DENV ...
Karthik Ramesh +7 more
doaj +1 more source
Dendritic Cell-Mediated Phagocytosis but Not Immune Activation Is Enhanced by Plasmin. [PDF]
PLoS ONE, 2015 Removal of dead cells in the absence of concomitant immune stimulation is essential for tissue homeostasis. We recently identified an injury-induced protein misfolding event that orchestrates the plasmin-dependent proteolytic degradation of necrotic ...
Rachael J Borg +9 more
doaj +1 more source
CALIX[4]ARENES METHYLENE BISPHOSPHONIC ACIDS EFFECT ON PLASMIN ACTIVITY [PDF]
Biotechnologia Acta, 2018 The aim of the work was to study plasmin inhibiting properties of calix[4]arenes functionalized by phosphonic acid remnants. The following methods were used: turbidimetry, analysis of enzyme activity for chromogenic substrates, evaluation of caseinolytic
O. I. Yusova +5 more
doaj +1 more source